Zobrazeno 1 - 10
of 452
pro vyhledávání: '"Joseph P. Huston"'
Autor:
Owen Y. Chao, Salil S. Pathak, Hao Zhang, Nathan Dunaway, Jay-Shake Li, Claudia Mattern, Susanne Nikolaus, Joseph P. Huston, Yi-Mei Yang
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-16 (2020)
Abstract The dopamine (DA) system has a profound impact on reward-motivated behavior and is critically involved in neurodevelopmental disorders, such as autism spectrum disorder (ASD). Although DA defects are found in autistic patients, it is not wel
Externí odkaz:
https://doaj.org/article/8c7c8b2c11bf46c996a63dea1d8651a5
Autor:
Susanne Nikolaus, Hans-Jörg Wittsack, Christina Antke, Markus Beu, Hubertus Hautzel, Cvetana Decheva, Eduards Mamlins, Yuriko Mori, Joseph P. Huston, Gerald Antoch, Hans-Wilhelm Müller
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Purpose: The 5-HT2A receptor (R) is known to modulate dopamine (DA) release in the mammalian brain. Altanserin (ALT) and 2,5-dimethoxy-4-iodoamphetamine (DOI) act as 5-HT2AR antagonist and agonist, respectively. In the present study, we assessed the
Externí odkaz:
https://doaj.org/article/924d4bbe6b6649778627c980bb761157
Autor:
Taygun C. Uzuneser, Jil Speidel, Georgios Kogias, An-Li Wang, Maria A. de Souza Silva, Joseph P. Huston, Iulia Zoicas, Stephan von Hörsten, Johannes Kornhuber, Carsten Korth, Christian P. Müller
Publikováno v:
Frontiers in Psychiatry, Vol 10 (2019)
Synaptic pruning is a critical refinement step during neurodevelopment, and schizophrenia has been associated with overpruning of cortical dendritic spines. Both human studies and animal models implicate disrupted-in-schizophrenia 1 (DISC1) gene as a
Externí odkaz:
https://doaj.org/article/b75556aa7edd4ceebdd96aa1db385e7b
Autor:
Susanne Nikolaus, Hans-Jörg Wittsack, Markus Beu, Christina Antke, Maria A. De Souza Silva, Frijthof Wickrath, Anja Müller-Lutz, Joseph P. Huston, Gerald Antoch, Hans-Wilhelm Müller, Hubertus Hautzel
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 12 (2018)
Purpose: The present study assessed the effects of the GABAA receptor (R) agonist muscimol (MUS), and the GABAAR antagonist bicuculline (BIC) on neocortical and subcortical radioligand binding to dopamine D2/3Rs in relation to motor and exploratory b
Externí odkaz:
https://doaj.org/article/189a1d6f30594548a954aa83ddc9b471
Autor:
Fernando J. Sialana, An-Li Wang, Benedetta Fazari, Martina Kristofova, Roman Smidak, Svenja V. Trossbach, Carsten Korth, Joseph P. Huston, Maria A. de Souza Silva, Gert Lubec
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Disrupted-in-schizophrenia 1 (DISC1) is a key protein involved in behavioral processes and various mental disorders, including schizophrenia and major depression. A transgenic rat overexpressing non-mutant human DISC1, modeling aberrant proteostasis
Externí odkaz:
https://doaj.org/article/c5a986ab4010481a8df67226d7f0f90a
Autor:
Maria A de Souza Silva, C. eMattern, C.I. eDecheva, Joseph P. Huston, A. eSadile, M. eBeu, H.W. eMüller, Susanne eNikolaus
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 10 (2016)
Purpose: Dopamine (DA), which does not cross the blood-brain barrier, has central and behavioral effects when administered via the nasal route. Neither the mechanisms of central action of intranasal dopamine (IN-DA), nor its mechanisms of diffusion a
Externí odkaz:
https://doaj.org/article/8d7052e5d98c48b8b44bbe194d0d20ed
Autor:
Susanne eNikolaus, Markus eBeu, Maria A De Souza Silva, Joseph P. Huston, Hubertus eHautzel, Claudia eMattern, Christina eAntke, Hans-Willhelm eMüller
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 10 (2016)
Externí odkaz:
https://doaj.org/article/d24adf036997458e9485e5e5516f24ff
Autor:
Susanne eNikolaus, Markus eBeu, Angelica M. De Souza Silva, Joseph P. Huston, Hubertus eHautzel, Claudia eMattern, Christina eAntke, Hans-Wilhelm eMüller
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 9 (2016)
Purpose: The present study assessed the influence of L-DOPA administration on neostriatal dopamine (DA) D2 receptor binding in relation to motor and exploratory behaviors in the rat.Methods: D2 receptor binding was measured in baseline, after challen
Externí odkaz:
https://doaj.org/article/d8e8c252fcba45eaad49b6e1fee45d67
Autor:
Susanne eNikolaus, Markus eBeu, Maria A De Souza Silva, Joseph P. Huston, Hubertus eHautzel, Owen Y Chao, Christina eAntke, Hans-Wilhelm eMüller
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 8 (2014)
Purpose: The present study assessed the influence of L-DOPA administration on neostriatal dopamine (DA) transporter (DAT) binding in relation to motor and exploratory behaviors in the rat.Methods: Rats received injections of 5 mg/kg L-DOPA, 10 mg/kg
Externí odkaz:
https://doaj.org/article/24c58c20bb5a4bf9bb136709b4f8fe17
Autor:
Philipp Ottis, Bianca Topic, Maarten Loos, Ka Wan Li, Maria A. de Souza Silva, Daniela Schulz, August B. Smit, Joseph P. Huston, Carsten Korth
Publikováno v:
PLoS ONE, Vol 8, Iss 10 (2013)
Externí odkaz:
https://doaj.org/article/df96eb7231cd45ddb47dc2b1f718aad4