Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Joseph P. Hoffmann"'
Autor:
Joseph P. Hoffmann, Akhilesh Srivastava, Haoran Yang, Naoki Iwanaga, T. Parks Remcho, Jenny L. Hewes, Rayshma Sharoff, Kejing Song, Elizabeth B. Norton, Jay K. Kolls, Janet E. McCombs
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract Lung tissue resident memory (TRM) cells are thought to play crucial roles in lung host defense. We have recently shown that immunization with the adjuvant LTA1 (derived from the A1 domain of E. coli heat labile toxin) admixed with OmpX from
Externí odkaz:
https://doaj.org/article/a125ff03d41c44a3a7c6aacd13ce9e42
Autor:
Yihui Wang, Joseph P. Hoffmann, Sarah M. Baker, Kerstin Höner zu Bentrup, William C. Wimley, Joseph A. Fuselier, Jacob P. Bitoun, Lisa A. Morici
Publikováno v:
BMC Microbiology, Vol 21, Iss 1, Pp 1-12 (2021)
Abstract Background Biofilms are microbial communities surrounded by a self-produced extracellular matrix which protects them from environmental stress. Bacteria within biofilms are 10- to 1000-fold more resistant to antibiotics, making it challengin
Externí odkaz:
https://doaj.org/article/a404412068b94913a0083574a378a3b7
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Lower respiratory infections are among the leading causes of morbidity and mortality worldwide. These potentially deadly infections are further exacerbated due to the growing incidence of antimicrobial resistance. To combat these infections there is
Externí odkaz:
https://doaj.org/article/28ee6f19cd31498a9119fe0e7377bbd2
Autor:
Joseph P. Hoffmann, Jessica K. Friedman, Yihui Wang, James B. McLachlan, Mimi C. Sammarco, Lisa A. Morici, Chad J. Roy
Publikováno v:
Frontiers in Microbiology, Vol 10 (2020)
Increased prevalence of antibiotic resistance in skin and soft tissue infections is a concerning public health challenge currently facing medical science. A combinatory, broad spectrum biocidal antiseptic has been developed (“ASP”) as a topically
Externí odkaz:
https://doaj.org/article/cf3afcab25b2431da8b68c20f296d889
Autor:
Dushen Chen, Akhilesh K. Srivastava, Justyna Dubrochowska, Lin Liu, Tiehai Li, Joseph P. Hoffmann, Jay K. Kolls, Geert‐Jan Boons
Publikováno v:
Chemistry – A European Journal. 29
Autor:
Jenisha Ghimire, Robert J. Hart, Anabel Soldano, Charles H. Chen, Shantanu Guha, Joseph P. Hoffmann, Kalen M. Hall, Leisheng Sun, Benjamin J. Nelson, Timothy K. Lu, Jay K. Kolls, Mario Rivera, Lisa A. Morici, William C. Wimley
Here, we describe the continued synthetic molecular evolution of a lineage of host-compatible antimicrobial peptides (AMP) intended for the treatment of wounds infected with drug-resistant, biofilm-forming bacteria. The peptides tested are variants o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66e05fd64737df06810f13364a677120
https://doi.org/10.1101/2022.12.01.518642
https://doi.org/10.1101/2022.12.01.518642
Autor:
Kerstin Höner zu Bentrup, Joseph P. Hoffmann, Yihui Wang, Lisa A. Morici, Sarah M. Baker, Jacob P. Bitoun, William C. Wimley, Joseph A. Fuselier
Publikováno v:
BMC Microbiology, Vol 21, Iss 1, Pp 1-12 (2021)
BMC Microbiology
BMC Microbiology
Background Biofilms are microbial communities surrounded by a self-produced extracellular matrix which protects them from environmental stress. Bacteria within biofilms are 10- to 1000-fold more resistant to antibiotics, making it challenging but imp
Autor:
Suling Zeng, Elisa Rosati, Carina Saggau, Berith Messner, Huikuan Chu, Yi Duan, Phillipp Hartmann, Yanhan Wang, Shengyun Ma, Wendy Jia Men Huang, Jihyung Lee, Sung Min Lee, Raquel Carvalho-Gontijo, Vivian Zhang, Joseph P. Hoffmann, Jay K. Kolls, Eyal Raz, David A. Brenner, Tatiana Kisseleva, Salomé LeibundGut-Landmann, Petra Bacher, Peter Stärkel, Bernd Schnabl
Publikováno v:
Cell Host & Microbe. 31:389-404.e7
Autor:
Jason W. Sahl, Lisa A. Morici, Chad J. Roy, Jacob P. Bitoun, Yihui Wang, Christopher Davitt, Sarah M. Baker, Joseph P. Hoffmann, James B. McLachlan, Nicole L. Kikendall, Kasi Russell Lodrigue, Paul Keim, Patrick S. Gellings, Erik W. Settles
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-10 (2021)
NPJ Vaccines
NPJ Vaccines
Burkholderia pseudomallei is a Gram-negative, facultative intracellular bacillus that causes the disease melioidosis. B. pseudomallei expresses a number of proteins that contribute to its intracellular survival in the mammalian host. We previously de
Autor:
Yihui Wang, Joseph A. Fuselier, Joseph P. Hoffmann, Chau-Wen Chou, Kerstin Höner zu Bentrup, Jacob P. Bitoun, Lisa A. Morici, William C. Wimley
Publikováno v:
Journal of Microbiology. 58:550-562
Gram-negative bacteria secrete outer membrane vesicles (OMVs) that play critical roles in intraspecies, interspecies, and bacteria-environment interactions. Some OMVs, such as those produced by Pseudomonas aeruginosa, have previously been shown to po