Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Joseph P. Hanig"'
Autor:
Luísa Camacho, Camila S Silva, Joseph P Hanig, Robert P Schleimer, Nysia I George, John F Bowyer
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0210273 (2019)
This work extends the understanding of how toxic exposures to amphetamine (AMPH) adversely affect the immune system and lead to tissue damage. Importantly, it determines which effects of AMPH are and are not due to pronounced hyperthermia. Whole bloo
Externí odkaz:
https://doaj.org/article/a86f1c2b74a04458bf85e3d87e501e38
Autor:
Serguei M. Liachenko, Natalya V. Sadovova, Arnold Tripp, Suman Ghorai, Anil K. Patri, Joseph P. Hanig, Jonathan E. Cohen, Ira Krefting
Publikováno v:
Journal of Magnetic Resonance Imaging. 56:1499-1504
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5acff018698341147165ddc9a121a020
https://doi.org/10.1002/jmri.28149
https://doi.org/10.1002/jmri.28149
Autor:
Leah E Latham, Vasily N Dobrovolsky, Shuliang Liu, John C Talpos, Joseph P Hanig, William Slikker, Cheng Wang, Fang Liu
Publikováno v:
Experimental Biology and Medicine. :153537022311681
Neurotoxicity assessments are generally performed using laboratory animals. However, as in vitro neurotoxicity models are continuously refined to reach adequate predicative concordance with in vivo responses, they are increasingly used for some endpo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b1fbadf1c5b90b2d783c792a3ba6602
https://doi.org/10.1177/15353702231168145
https://doi.org/10.1177/15353702231168145
Tauroursodeoxycholic acid (TUDCA) is neuroprotective in a chronic mouse model of Parkinson’s disease
Autor:
Sumit Sarkar, Aida G Guzman Lopez, Srinivasulu Chigurupati, Susan M. Burks, Nancy P. Gomez-Crisostomo, Bonnie L. Robinson, Claudia Escudero-Lourdes, Joseph P. Hanig, James Raymick, Sherry A. Ferguson, Elvis Cuevas
Publikováno v:
Nutritional Neuroscience. 25:1374-1391
Parkinson's disease (PD) is a progressive motor disease of unknown etiology. Although neuroprotective ability of endogenous bile acid, tauroursodeoxycholic acid (TUDCA), shown in various diseases, including an acute model of PD,the potential therapeu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7ab5afca9a8cf853e4a911968939049
https://doi.org/10.1080/1028415x.2020.1859729
https://doi.org/10.1080/1028415x.2020.1859729
Autor:
Anshul Srivastava, Joseph P. Hanig
Publikováno v:
Journal of Applied Toxicology. 41:996-1006
Neurotoxicity studies are important in the preclinical stages of drug development process, because exposure to certain compounds that may enter the brain across a permeable blood brain barrier damages neurons and other supporting cells such as astroc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61643ba7e35a3ff4dde31d8d3a02c3c4
https://doi.org/10.1002/jat.4098
https://doi.org/10.1002/jat.4098
Autor:
Anshul Srivastava, Sumit Sarkar, Merle G. Paule, Joseph P. Hanig, Jai P. Pandey, Serguei Liachenko, Geeta Negi
Publikováno v:
International Journal of Toxicology. 39:294-306
This study consisted of a qualitative and quantitative assessment of neuropathological changes in kainic acid (KA)–treated adult male rats. Rats were administered a single 10 mg/kg intraperitoneal injection of KA or the same volume of saline and sa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aff2907c025f32b9d416bab0463282f9
https://doi.org/10.1177/1091581820928497
https://doi.org/10.1177/1091581820928497
Autor:
Sumit Sarkar, Serena Tolani, John F. Bowyer, Joseph P. Hanig, James P. O'Callaghan, Susan M. Burks, Jade N. Hess
Publikováno v:
Neurotoxicology
Bacterial cell wall endotoxins, i.e. lipopolysaccharides (LPS), are some of the original compounds shown to evoke the classic signs of systemic inflammation/innate immune response and neuroinflammation. The term neuroinflammation often is used to inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::194ef79a7c3d7d4129b2b01951e51b69
https://doi.org/10.1016/j.neuro.2020.01.014
https://doi.org/10.1016/j.neuro.2020.01.014
Autor:
Serguei M, Liachenko, Natalya V, Sadovova, Arnold, Tripp, Suman, Ghorai, Anil K, Patri, Joseph P, Hanig, Jonathan E, Cohen, Ira, Krefting
Publikováno v:
Journal of magnetic resonance imaging : JMRIReferences. 56(5)
Currently, the gadolinium retention in the brain after the use of contrast agents is studied by TTProspective longitudinal.A total of 31 Sprague-Dawley rats administered gadodiamide IV (N = 8) or IP (N = 8), or saline IV (N = 6) or IP (N = 9) 4 days
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d479512f86fa09e6b9f8314d9b86fd72
https://pubmed.ncbi.nlm.nih.gov/35278003
https://pubmed.ncbi.nlm.nih.gov/35278003
Autor:
John F Bowyer, Karen M Tranter, Joseph P Hanig, Nathaniel M Crabtree, Robert P Schleimer, Nysia I George
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133315 (2015)
Methods were developed to evaluate the stability of rat whole blood expression obtained from RNA sequencing (RNA-seq) and assess changes in whole blood transcriptome profiles in experiments replicated over time. Expression was measured in globin-depl
Externí odkaz:
https://doaj.org/article/0a63fbce672f4e1189b09a4f0397f339
Autor:
Merle G. Paule, Xianlin Han, Qiang Gu, Peter A. Crawford, Cheng Wang, Shuliang Liu, William Slikker, Shannon E. Martin, Chunyan Wang, Tucker A. Patterson, Fang Liu, Jessica L. Frisch-Daiello, Joseph P. Hanig
Publikováno v:
Analytica Chimica Acta. 1037:87-96
Although numerous studies have raised public concerns regarding the safety of anesthetics including sevoflurane in children, the biochemical mechanisms leading to anesthetics-induced neurotoxicity remain elusive. Moreover, potential biomarker(s) for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7faaeafc23c4781a8a4cad8f14af28ff
https://doi.org/10.1016/j.aca.2017.11.052
https://doi.org/10.1016/j.aca.2017.11.052