Zobrazeno 1 - 10
of 359
pro vyhledávání: '"Joseph P. Grande"'
Autor:
Yun Liang, Elif Ozdogan, Michael J. Hansen, Hui Tang, Ishran Saadiq, Kyra L. Jordan, James D. Krier, Deep B. Gandhi, Joseph P. Grande, Lilach O. Lerman, Timucin Taner
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe immunomodulatory properties of mesenchymal stromal cells (MSC) have been well-characterized in in-vitro and in-vivo models. We have previously shown that liver MSC (L-MSC) are superior inhibitors of T-cell activation/proliferation, NK
Externí odkaz:
https://doaj.org/article/586a4f0a95384697991e199de658175c
Autor:
Aleksandar Denic, MD, PhD, Alessia Buglioni, MD, Sandor Turkevi-Nagy, MD, Mateo Velasquez Mejia, MD, Byron H. Smith, PhD, Walter D. Park, BS, Rashmi Subramani, MBBS, Aleksandra Kukla, MD, Tayyab S. Diwan, MD, Joseph P. Grande, MD, Mark D. Stegall, MD
Publikováno v:
Transplantation Direct, Vol 10, Iss 7, p e1652 (2024)
Background. Mesangial expansion (ME) is an understudied histologic lesion in renal allografts. The current Banff mm score is not reproducible and may miss important ME features. The study aimed to improve the quantification of ME using morphometry, a
Externí odkaz:
https://doaj.org/article/45bce354c7064644a3bb209d0d7bc610
Autor:
Silvana B. De Lorenzo, Alyssa M. Vrieze, Ruth A. Johnson, Karen R. Lien, Karl A. Nath, Vesna D. Garovic, Khashayarsha Khazaie, Joseph P. Grande
Publikováno v:
PLoS ONE, Vol 17, Iss 4 (2022)
Progression of virtually all forms of chronic kidney disease (CKD) is associated with activation of pro-inflammatory and pro-fibrotic signaling pathways. Despite extensive research, progress in identifying therapeutic targets to arrest or slow progre
Externí odkaz:
https://doaj.org/article/d023f009a676492d84a51e7a6764bade
Autor:
Sonja Suvakov, Ranine Ghamrawi, Hajrunisa Cubro, Haitao Tu, Wendy M. White, Yvonne S. Butler Tobah, Natasa M. Milic, Joseph P. Grande, Julie M. Cunningham, Fouad T. Chebib, Larissa G.P. Langhi Prata, Yi Zhu, Tamara Tchkonia, James L. Kirkland, Karl A. Nath, Aleksandar Milosavljevic, Vesna D. Garovic
Publikováno v:
EBioMedicine, Vol 70, Iss , Pp 103536- (2021)
Background: Preeclampsia is a pregnancy-specific hypertensive disorder characterized by proteinuria and/or multisystem involvement. Disease-specific therapy has yet to be developed due to the lack of understanding of underlying mechanism(s). We postu
Externí odkaz:
https://doaj.org/article/2d6a2d2b00854797803a0525e383c515
Autor:
Sonja Suvakov, Hajrunisa Cubro, Wendy M. White, Yvonne S. Butler Tobah, Tracey L. Weissgerber, Kyra L. Jordan, Xiang Y. Zhu, John R. Woollard, Fouad T. Chebib, Natasa M. Milic, Joseph P. Grande, Ming Xu, Tamara Tchkonia, James L. Kirkland, Lilach O. Lerman, Vesna D. Garovic
Publikováno v:
Biology of Sex Differences, Vol 10, Iss 1, Pp 1-13 (2019)
Abstract Background Preeclampsia is a pregnancy-specific hypertensive disorder characterized by impaired angiogenesis. We postulate that senescence of mesenchymal stem cells (MSC), multipotent cells with pro-angiogenic activities, is one of the mecha
Externí odkaz:
https://doaj.org/article/130b90b7b9b840e48df08fc38360e418
Autor:
Matthew R. D’Costa, Lauren A. Dalvin, Sandhya Manohar, Leo J. Maguire, Joseph P. Grande, Wilson I. Gonsalves, Samih H. Nasr, Marie C. Hogan
Publikováno v:
Kidney Medicine, Vol 1, Iss 2, Pp 71-74 (2019)
Crystalglobulinemia, a rare manifestation of monoclonal gammopathy, results from vascular deposition of crystallized monoclonal proteins leading to tissue injury. A 56-year-old man initially presented several years earlier with migratory polyarthralg
Externí odkaz:
https://doaj.org/article/d36c6c8727a640f78764d944b0879fef
Autor:
Samih H. Nasr, Julie A. Vrana, Surendra Dasari, Frank Bridoux, Mary E. Fidler, Sihem Kaaki, Nathalie Quellard, Alexia Rinsant, Jean Michel Goujon, Sanjeev Sethi, Fernando C. Fervenza, Lynn D. Cornell, Samar M. Said, Ellen D. McPhail, Loren P. Herrera Hernandez, Joseph P. Grande, Marie C. Hogan, John C. Lieske, Nelson Leung, Paul J. Kurtin, Mariam P. Alexander
Publikováno v:
Kidney International Reports, Vol 3, Iss 1, Pp 56-64 (2018)
Fibrillary glomerulonephritis (FGN) is a rare disease with unknown pathogenesis and a poor prognosis. Until now, the diagnosis of this disease has required demonstration of glomerular deposition of randomly oriented fibrils by electron microscopy tha
Externí odkaz:
https://doaj.org/article/5a6bfb80b6b44dfca60e41125f0467d5
Autor:
Joseph P. Grande, Lilach O. Lerman, Stephen J. Textor, Karl A. Nath, Bruce E. Knudsen, Adeel S. Zubair, Stella P. Hartono
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 9, Pp 18640-18656 (2013)
Activation of the renin-angiotensin-aldosterone system plays a critical role in the development of chronic renal damage in patients with renovascular hypertension. Although angiotensin II (Ang II) promotes oxidative stress, inflammation, and fibrosis
Externí odkaz:
https://doaj.org/article/1d13de666ff64ea4b70867fb340a7804
Autor:
Sonu Kashyap, Sean Engel, Mazen Osman, Yousif Al-Saiegh, Asarn Wongjarupong, Joseph P. Grande
Publikováno v:
PeerJ, Vol 4, p e1736 (2016)
Purpose. Type 2 diabetes is the leading cause of end stage renal disease in the United States. Atherosclerotic renal artery stenosis is commonly observed in diabetic patients and impacts the rate of renal and cardiovascular disease progression. We so
Externí odkaz:
https://doaj.org/article/f450b122ee9945fcb0932b3985ef5f52
Autor:
Justin G. Peacock, Joseph P. Grande
Publikováno v:
PeerJ, Vol 3, p e809 (2015)
Purpose. The authors proposed that introducing real patients into a pathology classroom early in medical education would help integrate fundamental principles and disease pathology with clinical presentation and medical history.Methods. Three patient
Externí odkaz:
https://doaj.org/article/32e9f40f2e914a0aa4095b78e47119ad