Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Joseph P. Clarke"'
Autor:
Joseph P. Clarke, Patricia A. Thibault, Sakina Fatima, Hannah E. Salapa, Subha Kalyaanamoorthy, Aravindhan Ganesan, Michael C. Levin
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
The RNA binding protein heterogeneous nuclear ribonucleoprotein A1 (A1) regulates RNA metabolism, which is crucial to maintaining cellular homeostasis. A1 dysfunction mechanistically contributes to reduced cell viability and loss, but molecular mecha
Externí odkaz:
https://doaj.org/article/e9a6b9cc5b554f6ca0e0e99458443344
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) is a member of the hnRNP family of conserved proteins that is involved in RNA transcription, pre-mRNA splicing, mRNA transport, protein translation, microRNA processing, telomere maintenance and t
Externí odkaz:
https://doaj.org/article/14c7c1bb5a7e44058c7fd0bfa66fb509
Publikováno v:
Communications Earth & Environment, Vol 3, Iss 1, Pp 1-8 (2022)
Strongly correlated changes between the amplitude of the seasonal cycle in temperature and the annual mean evaporative fraction indicate long-term drying in the Amazon, according to climate reanalyses and Earth System Model projections.
Externí odkaz:
https://doaj.org/article/7e811a3671da4ddabad5c8b0aad71b62
Autor:
Vitaly Chasov, Regina Mirgayazova, Ekaterina Zmievskaya, Raniya Khadiullina, Aygul Valiullina, Joseph Stephenson Clarke, Albert Rizvanov, Matthias G. J. Baud, Emil Bulatov
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
The transcription factor p53 is a key tumor suppressor that is inactivated in almost all cancers due to either point mutations in the TP53 gene or overexpression of its negative regulators. The p53 protein is known as the “cellular gatekeeper” fo
Externí odkaz:
https://doaj.org/article/bd5dac044856409a9eb9ccd1aa8db9b8
Publikováno v:
Molecular Plant-Microbe Interactions, Vol 14, Iss 10, Pp 1131-1139 (2001)
The Arabidopsis NPR1 protein is an essential regulatory component of systemic acquired resistance (SAR). Mutations in the NPR1 gene completely block the induction of SAR by signals such as salicylic acid (SA). An Arabidopsis mutant, snc1 (suppressor
Externí odkaz:
https://doaj.org/article/1cf0895bd5624b539d74b23f3adc488c
Autor:
Joseph P Clarke, Karen M Mearow
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68978 (2013)
Previous studies have suggested that the small heat shock protein, HspB1, has a direct influence on the dynamics of cytoskeletal elements, in particular, filamentous actin (F-actin) polymerization. In this study we have assessed the influence of HspB
Externí odkaz:
https://doaj.org/article/00894c63b978429cba1c5ef8079b34b8
Autor:
Darryl Hudson, David Guevara, Mahmoud W Yaish, Carol Hannam, Nykoll Long, Joseph D Clarke, Yong-Mei Bi, Steven J Rothstein
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e26765 (2011)
Chloroplast development is an important determinant of plant productivity and is controlled by environmental factors including amounts of light and nitrogen as well as internal phytohormones including cytokinins and gibberellins (GA). The paralog GAT
Externí odkaz:
https://doaj.org/article/4eeb9eb265f74a3186eac8debacef722
Publikováno v:
Neurochemistry International. 105:64-79
Alzheimer's disease is a progressive neurodegenerative disease that has links with other conditions that can often be modified by dietary and life-style interventions. In particular, coconut oil has received attention as having potentially having ben
Autor:
Karen M. Mearow, Joseph P. Clarke
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 7, p e68978 (2013)
PLoS ONE, Vol 8, Iss 7, p e68978 (2013)
Previous studies have suggested that the small heat shock protein, HspB1, has a direct influence on the dynamics of cytoskeletal elements, in particular, filamentous actin (F-actin) polymerization. In this study we have assessed the influence of HspB
Publikováno v:
Journal of neuroscience research. 87(14)
Neurofibrillary tangles and amyloid plaques are considered to be hallmarks of Alzheimer's disease (AD), and the toxic effects of amyloid-beta peptide (A beta) lead to activation of stress-related signaling and neuronal loss. The small heat shock prot