Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Joseph P., Gardner"'
Publikováno v:
mSystems, Vol 8, Iss 1 (2023)
ABSTRACT The open ocean is an extremely competitive environment, partially due to the dearth of nutrients. Trichodesmium erythraeum, a marine diazotrophic cyanobacterium, is a keystone species in the ocean due to its ability to fix nitrogen and leak
Externí odkaz:
https://doaj.org/article/bea9b36841d446c29b45405aa09d1339
Autor:
Lih-Ling Lin, Guoxing Wang, Joseph P. Gardner, Hong Wang, Suman Shanker, Eicke Latz, Jeffrey S. Culp, Bruce Allen Lefker, Frank Lovering, Daniel C. Schmitt, Dana Castro, Ann Aulabaugh, Ryan Nistler, Timothy A. Subashi, Jimson Wong, Ken Dower, Steven J. Hawrylik, Olga Plotnikova, Karen L. Leach, Wen Lin, Fabien Vincent, James F. Smith, Amy Brault, Darren Dumlao, David Hepworth, Justin Hall, Mark Horn, Shawn Weng, Jing Li, Nootaree Niljanskul, William B. Snyder, Edyta Tyminski, Douglas T. Golenbock, David W. Lin, Leslie Anthony Dakin, Dikran Aivazian, Lyn H. Jones, John I. Trujillo, Ming Chen, Betsy Pierce, Peter Jones
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 9, p e0184843 (2017)
PLoS ONE, Vol 12, Iss 9, p e0184843 (2017)
Cyclic GMP-AMP synthase (cGAS) initiates the innate immune system in response to cytosolic dsDNA. After binding and activation from dsDNA, cGAS uses ATP and GTP to synthesize 2', 3' -cGAMP (cGAMP), a cyclic dinucleotide second messenger with mixed 2'
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b467aadfb55b2af9efbce775d0740c57
http://europepmc.org/articles/PMC5608272
http://europepmc.org/articles/PMC5608272
Autor:
James R. Merson, Lianchun Chen, In-Jeong Kim, Daisy Hammond, Clare Christy, Tharsika Tharmanathan, R. Brad Jones, Heather A. Simmons, Mario A. Ostrowski, Kerry A Beheler, Eva G. Rakasz, Jakir Hussain Ullah, Neil C. Sheppard, Carla Fernandes, Dusko Trajkovic, Peter T. Loudon, Douglas F. Nixon, Jonah B. Sacha, Philip A. Castrovinci, Jason S. Reed, Melanie Rieger, Patrick B. Lappin, Ingrid M. Pruimboom-Brees, Daniel Schenkman, Juliann Janies, Ningli Zhang, Joseph P. Gardner, Sing Rong, Douglas H Gebhard, Ahmed M. Shoieb, Michael J. McCluskie, Shari M. Piaskowski, Klaus Rumpel, Laura Newman, Francesca A. Nimityongskul, Robert J Gifford, Brian G. Pierce, Frederike von Pelchrzim, David A. Goodwin, Sophie Muscat-King, Samantha E. Wildeboer
Publikováno v:
The Journal of Immunology. 189:1467-1479
The expression of endogenous retrotransposable elements, including long interspersed nuclear element 1 (LINE-1 or L1) and human endogenous retrovirus, accompanies neoplastic transformation and infection with viruses such as HIV. The ability to engend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7367f62dea46e68bcbd19dc7596b7d1
https://doi.org/10.4049/jimmunol.1200079
https://doi.org/10.4049/jimmunol.1200079
Autor:
John P. Kane, Omar L. Francone, Clive R. Pullinger, Jian Zhu, John F. Thompson, Joseph P. Gardner
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 7, Pp 1330-1339 (2009)
Given the increased prevalence of cardiovascular disease in the world, the search for genetic variations controlling the levels of risk factors associated with the development of the disease continues. Multiple genetic association studies suggest the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68a7a6e6b506df04045ccfc4e7b8efb7
http://www.sciencedirect.com/science/article/pii/S0022227520307811
http://www.sciencedirect.com/science/article/pii/S0022227520307811
Autor:
Mark Joseph Neveu, Ellen Chuang, Michael D. Robbins, James M. Duerr, Rodney Morgan, Joseph P. Gardner, Craig B. Thompson, John E. Hambor, Matthew G. Vander Heiden, Timothy Scott Fisher
Publikováno v:
Immunity. 13:313-322
CD28 and CTLA-4 are related members of a family of T lymphocyte cell surface receptors that function to regulate T cell activation. We have found that the cytoplasmic domains of both CTLA-4 and CD28 can associate with members of the PP2A family of se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd79fd7bad0f64e43240a030be1f5520
https://doi.org/10.1016/s1074-7613(00)00031-5
https://doi.org/10.1016/s1074-7613(00)00031-5
Autor:
William H. Brissette, Jeffrey Herbert Hanke, Weringer Elora Jeanne, Brian A. Pollok, Patricia A. Connelly, Joseph P. Gardner, Robert L. Dow, Paul S. Changelian
Publikováno v:
Journal of Biological Chemistry. 271:695-701
Here, we have studied the activity of a novel protein-tyrosine kinase inhibitor that is selective for the Src family of tyrosine kinases. We have focused our study on the effects of this compound on T cell receptor-induced T cell activation, a proces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f3e0efff29a8456b2251157b176483a
https://doi.org/10.1074/jbc.271.2.695
https://doi.org/10.1074/jbc.271.2.695
Autor:
Timothy Scott Fisher, Mark Joseph Neveu, Bradley C. Guarino, Maria-Luisa Alegre, James M. Duerr, David H. Singleton, D. Nunez, Glenn C. Andrews, Joseph P. Gardner
Publikováno v:
Peptides for the New Millennium ISBN: 0792364457
CTLA-4, transiently expressed on the surface of activated T-cells, binds to antigen presenting cell ligands B7.1 and B7.2 with 100 fold higher affinity than it's competitive receptor, CD28. CD28 promotes T-cell activation upon such binding, however,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc5c3e04b15a0f5c929968e1bc16af7b
https://doi.org/10.1007/0-306-46881-6_238
https://doi.org/10.1007/0-306-46881-6_238
Autor:
Joseph M. Merenda, David P. Dean, Joseph P. Gardner, Patricia A. Connelly, Melissa Cronan, Julio E. Celis
Publikováno v:
Electrophoresis. 15(3-4)
We report a simple method, designated "spot transfer", where known proteins are excised and eluted from a two-dimensional (2-D) gel run on one gel system to transfer identification of the proteins to a different 2-D gel system by comigration with a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::843d122e42e6481685aa7d3e06684ed0
https://pubmed.ncbi.nlm.nih.gov/8055881
https://pubmed.ncbi.nlm.nih.gov/8055881
Autor:
H. Wang, Carol B. Donovan, Robbin Alpert, Ronald P. Gladue, Vahe Bedian, Joseph P. Gardner, Edward J. Natoli, Timothy Joseph Paradis, Richard M. Shepard, J. Wentland
Publikováno v:
Journal of Clinical Oncology. 24:2539-2539
2539 Background: CD40 is expressed on B-cells, monocytes, dendritic cells, other normal tissues and tumors. Previous studies showed that CD40 stimulation enhances antigen presentation, breaks tolerance, bypasses T-cell help, and induces apoptosis in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41ca79306a2740f9d5763b6c75e35b09
https://doi.org/10.1200/jco.2006.24.18_suppl.2539
https://doi.org/10.1200/jco.2006.24.18_suppl.2539
Autor:
Chivin Sun, Joseph S. Gardner, Gary Long, Cyril Bajracharya, Aaron Thurber, Alex Punnoose, Rene G. Rodriguez, Joshua J. Pak
Publikováno v:
Chemistry of Materials; May2010, Vol. 22 Issue 9, p2699-2701, 3p