Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Joseph P McElroy"'
Autor:
Joseph P McElroy, Steven G Carmella, Alisa K Heskin, Mei Kuen Tang, Sharon E Murphy, Sarah A Reisinger, Joni A Jensen, Dorothy K Hatsukami, Stephen S Hecht, Peter G Shields
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218386 (2019)
The urinary metabolites "prostaglandin E2 metabolite" (PGE-M) and (Z)-7-[1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]hept-5-enoic acid (8-iso-PGF2α) are biomarkers of inflammation and oxidative damage, respectively, and are
Externí odkaz:
https://doaj.org/article/827b97009ae249e298832caa3c92089d
Autor:
Devki Patel, Joseph P. McElroy, Daniel Y. Weng, Kamel Sahar, Sarah A. Reisinger, Jo L. Freudenheim, Mark D. Wewers, Peter G. Shields, Min-Ae Song
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Lung cancer exhibits sex-biased molecular characteristics and epidemiological trends, suggesting a need for sex-specific approaches to understanding its etiology and treatment. DNA methylation alterations play critical roles in lung carcinog
Externí odkaz:
https://doaj.org/article/413d5151e0d44b7fb069738a4d0c5a80
Autor:
Wei Meng, Joseph P McElroy, Stefano Volinia, Jeff Palatini, Sarah Warner, Leona W Ayers, Kamalakannan Palanichamy, Arnab Chakravarti, Tim Lautenschlaeger
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64393 (2013)
MicroRNAs regulate several aspects of tumorigenesis and cancer progression. Most cancer tissues are archived formalin-fixed and paraffin-embedded (FFPE). While microRNAs are a more stable form of RNA thought to withstand FFPE-processing and degradati
Externí odkaz:
https://doaj.org/article/2923a918b7ad4e1a86b74f73f53a6960
Autor:
Min-Ae Song, Kellie M. Mori, Joseph P. McElroy, Jo L. Freudenheim, Daniel Y. Weng, Sarah A. Reisinger, Theodore M. Brasky, Mark D. Wewers, Peter G. Shields
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-12 (2023)
Abstract Background Cigarette smoking and aging are the main risk factors for pulmonary diseases, including cancer. Epigenetic aging may explain the relationship between smoking, electronic cigarette vaping, and pulmonary health. No study has examine
Externí odkaz:
https://doaj.org/article/21f2f1b269dd4f138393216a2b4f7964
Autor:
Maria C. Cuitiño, DVM, PhD, Jessica L. Fleming, PhD, Sagarika Jain, MS, Ashley Cetnar, PhD, Ahmet S. Ayan, PhD, Jeffrey Woollard, PhD, Heather Manring, PhD, Wei Meng, PhD, Joseph P. McElroy, PhD, Dukagjin M. Blakaj, MD, PhD, Nilendu Gupta, PhD, Arnab Chakravarti, MD
Publikováno v:
Advances in Radiation Oncology, Vol 8, Iss 4, Pp 101201- (2023)
Purpose: Increasing evidence suggests that ultra-high-dose-rate (UHDR) radiation could result in similar tumor control as conventional (CONV) radiation therapy (RT) while reducing toxicity to surrounding healthy tissues. Considering that radiation to
Externí odkaz:
https://doaj.org/article/666a2dc7e6284d58b0a53422ca351674
Autor:
Amarnath Singh, Garrett Kinnebrew, Ping-Ching Hsu, Daniel Y. Weng, Min-Ae Song, Sarah A. Reisinger, Joseph P. McElroy, Brittney Keller-Hamilton, Amy K. Ferketich, Jo L. Freudenheim, Peter G. Shields
Publikováno v:
Metabolites, Vol 13, Iss 8, p 899 (2023)
Obesity in children and adolescents has increased globally. Increased body mass index (BMI) during adolescence carries significant long-term adverse health outcomes, including chronic diseases such as cardiovascular disease, stroke, diabetes, and can
Externí odkaz:
https://doaj.org/article/d9faa269de9a4847a399c1c58ca4e111
Autor:
Kellie M. Mori, Joseph P. McElroy, Daniel Y. Weng, Sangwoon Chung, Paolo Fadda, Sarah A. Reisinger, Kevin L. Ying, Theodore M. Brasky, Mark D. Wewers, Jo L. Freudenheim, Peter G. Shields, Min-Ae Song
Publikováno v:
EBioMedicine, Vol 85, Iss , Pp 104301- (2022)
Summary: Background: Mitochondrial DNA copy number (mtCN) maintains cellular function and homeostasis, and is linked to nuclear DNA methylation and gene expression. Increased mtCN in the blood is associated with smoking and respiratory disease, but h
Externí odkaz:
https://doaj.org/article/4a7cfecacdf249ceb5519c4fc308155a
Autor:
Peter G. Shields, Kevin L. Ying, Theodore M. Brasky, Jo L. Freudenheim, Zihai Li, Joseph P. McElroy, Sarah A. Reisinger, Min-Ae Song, Daniel Y. Weng, Mark D. Wewers, Noah B. Whiteman, Yiping Yang, Ewy A. Mathé
Publikováno v:
Microorganisms, Vol 11, Iss 6, p 1405 (2023)
Smokers (SM) have increased lung immune cell counts and inflammatory gene expression compared to electronic cigarette (EC) users and never-smokers (NS). The objective of this study is to further assess associations for SM and EC lung microbiomes with
Externí odkaz:
https://doaj.org/article/86e29905cafc41bba651243ac132bcd6
Autor:
Qiyu Luo, Shu Chen, Hai Nian, Qibing Ma, Yuyao Ding, Qinwen Hao, Jiping Wei, Jinesh D. Patel, Joseph Scott McElroy, Yaoguang Liu, Yong Chen
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6629 (2023)
Eleusine indica (goosegrass) is a problematic weed worldwide known for its multi-herbicide tolerance/resistance biotype. However, a genetic transformation method in goosegrass has not been successfully established, making a bottleneck for functional
Externí odkaz:
https://doaj.org/article/4407a39201804599b58450e3f1bb1040
Autor:
Norman L. Lehman, Nathalie Spassky, Müge Sak, Amy Webb, Cory T. Zumbar, Aisulu Usubalieva, Khaled J. Alkhateeb, Joseph P. McElroy, Kirsteen H. Maclean, Paolo Fadda, Tom Liu, Vineela Gangalapudi, Jamie Carver, Zied Abdullaev, Cynthia Timmers, John R. Parker, Christopher R. Pierson, Bret C. Mobley, Murat Gokden, Eyas M. Hattab, Timothy Parrett, Ralph X. Cooke, Trang D. Lehman, Stefan Costinean, Anil Parwani, Brian J. Williams, Randy L. Jensen, Kenneth Aldape, Akshitkumar M. Mistry
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/1f6fc156e6604e9bbe9bcaf99d265dea