Zobrazeno 1 - 10
of 588
pro vyhledávání: '"Joseph P Lynch"'
Autor:
Anna-Maria Hoffmann-Vold, Stephen Samuel Weigt, Vyacheslav Palchevskiy, Elizabeth Volkmann, Rajan Saggar, Ning Li, Øyvind Midtvedt, May Brit Lund, Torhild Garen, Michael C Fishbein, Abbas Ardehali, David J Ross, Thor Ueland, Pål Aukrust, Joseph P Lynch, Robert M Elashoff, Øyvind Molberg, John A Belperio
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0206545 (2018)
BACKGROUND:Dysregulation of Fractalkine (CX3CL1) and its receptor CX3CR1 has been linked to the pathobiology of chronic inflammatory conditions. We explored CX3CL1 in systemic sclerosis (SSc) related progressive interstitial lung disease (ILD) and pu
Externí odkaz:
https://doaj.org/article/35807d8610404e829ad34bc846b6ab31
Autor:
S Samuel Weigt, Xiaoyan Wang, Vyacheslav Palchevskiy, Aric L Gregson, Naman Patel, Ariss DerHovanessian, Michael Y Shino, David M Sayah, Shirin Birjandi, Joseph P Lynch, Rajan Saggar, Abbas Ardehali, David J Ross, Scott M Palmer, David Elashoff, John A Belperio
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169894 (2017)
BACKGROUND:Chronic Lung Allograft Dysfunction (CLAD) is the main limitation to long-term survival after lung transplantation. Although CLAD is usually not responsive to treatment, earlier identification may improve treatment prospects. METHODS:In a n
Externí odkaz:
https://doaj.org/article/51c2cfff00ed41e99d5e67da95b3a38c
Autor:
Michael Y Shino, S Samuel Weigt, Ning Li, Vyacheslav Palchevskiy, Ariss Derhovanessian, Rajan Saggar, David M Sayah, Richard H Huynh, Aric L Gregson, Michael C Fishbein, Abbas Ardehali, David J Ross, Joseph P Lynch, Robert M Elashoff, John A Belperio
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180281 (2017)
Since the pathogenesis of chronic lung allograft dysfunction (CLAD) remains poorly defined with no known effective therapies, the identification and study of key events which increase CLAD risk is a critical step towards improving outcomes. We hypoth
Externí odkaz:
https://doaj.org/article/f26eb751205e4bdab74fb06f6ebd3e38
Autor:
Meng Wang, Edmund Cotter, Ya-Juan Wang, Xu Fu, Angela L. Whittsette, Joseph W. Lynch, R. Luke Wiseman, Jeffery W. Kelly, Angelo Keramidas, Ting-Wei Mu
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-20 (2022)
Abstract Background Genetic variants in the subunits of the gamma-aminobutyric acid type A (GABAA) receptors are implicated in the onset of multiple pathologic conditions including genetic epilepsy. Previous work showed that pathogenic GABAA subunits
Externí odkaz:
https://doaj.org/article/569f39d2a4334662858040e0811c4d49
Autor:
Jacqui M. Couldrick, Andrew P. Woodward, M. Denika C. Silva, Joseph T. Lynch, Diana M. Perriman, Christian J. Barton, Jennie M. Scarvell
Publikováno v:
PLoS ONE, Vol 18, Iss 4 (2023)
Objective To identify individual characteristics associated with outcomes following combined first-line interventions for knee osteoarthritis. Methods MEDLINE, CINAHL, Scopus, Web of Science Core Collection and the Cochrane library were searched. Stu
Externí odkaz:
https://doaj.org/article/2527e590aacc4985bb78fec534b35536
Autor:
James A. Karlowsky, Andrew J. Walkty, Melanie R. Baxter, Heather J. Adam, Philippe R. S. Lagacé-Wiens, Frank Schweizer, Denice Bay, Joseph P. Lynch, Michael R. Mulvey, George G. Zhanel
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 4 (2022)
ABSTRACT Cefiderocol was evaluated by broth microdilution versus 1,050 highly antimicrobial-resistant Pseudomonas aeruginosa clinical isolates from the CANWARD study (2007 to 2019). Overall, 98.3% of isolates remained cefiderocol susceptible (MIC,
Externí odkaz:
https://doaj.org/article/5077a3bc87b34505b0c469eceb87ec6c
Publikováno v:
Journal of Fungi, Vol 9, Iss 7, p 744 (2023)
The Guest Editors Dr [...]
Externí odkaz:
https://doaj.org/article/f36cdf2ce194403b9b5d6fa10224c2dd
Autor:
Xiumin Chen, Katie A. Wilson, Natascha Schaefer, Lachlan De Hayr, Mark Windsor, Emmanuel Scalais, Germaine van Rijckevorsel, Katrien Stouffs, Carmen Villmann, Megan L. O’Mara, Joseph W. Lynch, Robert J. Harvey
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Glycine receptors (GlyRs) containing the α2 subunit govern cell fate, neuronal migration and synaptogenesis in the developing cortex and spinal cord. Rare missense variants and microdeletions in the X-linked GlyR α2 subunit gene (GLRA2) have been a
Externí odkaz:
https://doaj.org/article/743362d01b994827a23b902182262cc5
Publikováno v:
Journal of Antimicrobial Chemotherapy. 78:i2-i7
Background Streptococcus pneumoniae continues to be an important bacterial pathogen associated with invasive (e.g. bacteraemia, meningitis) and non-invasive (e.g. community-acquired respiratory tract) infections worldwide. Surveillance studies conduc
Autor:
John A. Belperio, Faisal Shaikh, Fereidoun Abtin, Michael C. Fishbein, Rajan Saggar, Edmund Tsui, Joseph P. Lynch, III
Publikováno v:
EClinicalMedicine, Vol 37, Iss , Pp 100966- (2021)
Sarcoidosis is a poorly understood granulomatous disease that involves the lungs and/or intrathoracic lymph nodes in more than 90% of cases. Although pulmonary sarcoidosis is the leading cause of mortality in this disease, this review focuses on thre
Externí odkaz:
https://doaj.org/article/23818fe547bd4ea288eeed78f5d4d682