Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Joseph P Jarvis"'
Autor:
Katharine E. Stott, Jason T. Mohabir, Katharine Bowers, Jennifer L. Tenor, Dena L. Toffaletti, Jennifer Unsworth, Ana Jimenez-Valverde, Ajisa Ahmadu, Melanie Moyo, Ebbie Gondwe, Wezi Chimang’anga, Madalitso Chasweka, David S. Lawrence, Joseph N. Jarvis, Tom Harrison, William Hope, David G. Lalloo, Henry C. Mwandumba, John R. Perfect, Christina A. Cuomo
Publikováno v:
mBio, Vol 15, Iss 10 (2024)
ABSTRACT Cryptococcal meningitis causes an estimated 112,000 global deaths per annum. Genomic and phenotypic features of the infecting strain of Cryptococcus spp. have been associated with outcomes from cryptococcal meningitis. Additionally, populati
Externí odkaz:
https://doaj.org/article/5c0a7db0000344608f0923009f12b36b
Autor:
Tadeo Kiiza Kandole, Michael Okirwoth, Thomas S. Harrison, Fiona Cresswel, Katherine Fielding, David Moore, David Boulware, David Meya, Joseph N. Jarvis, Jayne Ellis, Enock Kagimu, Laura Nsangi, Gila Hale, Ananta Bangdiwala, Timothy Mugabi, Jane Gakuru, Asmus Tukundane, Enos Kigozi
Publikováno v:
Wellcome Open Research, Vol 9 (2024)
Background Mortality associated with HIV-associated cryptococcal meningitis remains high even in the context of clinical trials (24–45% at 10 weeks); mortality at 12-months is up to 78% in resource limited settings. Co-prevalent tuberculosis (TB) i
Externí odkaz:
https://doaj.org/article/be66e824ef7a4c3d83a5fe4fc0d45a61
Autor:
Joseph P Jarvis, Laura B Scheinfeldt, Sameer Soi, Charla Lambert, Larsson Omberg, Bart Ferwerda, Alain Froment, Jean-Marie Bodo, William Beggs, Gabriel Hoffman, Jason Mezey, Sarah A Tishkoff
Publikováno v:
PLoS Genetics, Vol 8, Iss 4, p e1002641 (2012)
African Pygmy groups show a distinctive pattern of phenotypic variation, including short stature, which is thought to reflect past adaptation to a tropical environment. Here, we analyze Illumina 1M SNP array data in three Western Pygmy populations fr
Externí odkaz:
https://doaj.org/article/d044d90fb4fe4c1cbac5c8237ae7f6fc
Autor:
Mosepele Mosepele, Kara Bennett, Tendani Gaolathe, Joseph M. Makhema, Mompati Mmalane, Molly Pretorius Holme, Refeletswe Lebelonyane, Omolola Ometoruwa, Lisa A. Mills, Kathleen M. Powis, Jean Leidner, Joseph N. Jarvis, Neo M. Tapela, Tiny Masupe, Lucky Mokgatlhe, Virginia A. Triant, Kathleen E. Wirth, Thato Moshomo, Shahin Lockman
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract In a population-based representative sample of adults residing in 22 communities in Botswana, a southern African country with high HIV prevalence, 1 in 4 individuals had high blood pressure. High blood pressure was less prevalent in adults w
Externí odkaz:
https://doaj.org/article/174ff52153ae468a92b25f628227a934
Autor:
David S. Lawrence, Agnes Ssali, Neo Moshashane, Georgina Nabaggala, Lebogang Maphane, Thomas S. Harrison, David Meya, Joseph N. Jarvis, Janet Seeley
Publikováno v:
SSM: Qualitative Research in Health, Vol 4, Iss , Pp 100350- (2023)
HIV-associated cryptococcal meningitis remains a key driver of AIDS-related mortality. Mortality is twice as high in those who present later to care and with severe symptoms such as confusion. We embedded a qualitative methods study within a randomis
Externí odkaz:
https://doaj.org/article/5d46d24a20734857a77e00e6a18fe64d
Autor:
Catriona Macrae, Jayne Ellis, Suzanne H. Keddie, Jane Falconer, John Bradley, Ruth Keogh, Oliver Baerenbold, Heidi Hopkins, Joseph N. Jarvis
Publikováno v:
BMC Infectious Diseases, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background The incidence of cryptococcosis amongst HIV-negative persons is increasing. Whilst the excellent performance of the CrAg testing in people living with HIV is well described, the diagnostic performance of the CrAg LFA has not been
Externí odkaz:
https://doaj.org/article/a3addcb9251e4e7ebc6a2aaeae64cfd2
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Background Research into life-threatening illnesses which require emergency hospitalisation is essential. This group of patients is unique in that they are experiencing an unfolding emergency when they are approached, enrolled, and followed
Externí odkaz:
https://doaj.org/article/855965943b8e4040a8372a233283e89f
Publikováno v:
Cambridge Prisms: Precision Medicine, Vol 1 (2023)
An ever-expanding annotation of the human genome sequence continues to promise a new era of precision medicine. Advances in knowledge management and the ability to leverage genetic information to make clinically relevant, predictive, diagnostic, and
Externí odkaz:
https://doaj.org/article/d4a954df6cd0406d8a38b1f47e8eb4ad
Autor:
David S Lawrence, Agnes Ssali, Neo Moshashane, Georgina Nabaggala, Lebogang Maphane, Thomas S Harrison, David B Meya, Joseph N Jarvis, Janet Seeley
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 10, p e0010825 (2022)
BackgroundThe AMBITION-cm trial for HIV-associated cryptococcal meningitis demonstrated that a single, high-dose of liposomal amphotericin (AmBisome) plus 14-days of oral flucytosine and fluconazole was non-inferior in terms of all-cause mortality to
Externí odkaz:
https://doaj.org/article/0152e3e136a94921a4024b6f2e795248
Autor:
David B. Meya, Lillian Tugume, Vennie Nabitaka, Proscovia Namuwenge, Sam Phiri, Rita Oladele, Bilkisu Jibrin, Mojisola Mobolaji-Bello, Cecilia Kanyama, Werner Maokola, Sayoki Mfinanga, Cordelia Katureebe, Ikechukwu Amamilo, Brian Ngwatu, Joseph N. Jarvis, Thomas S. Harrison, Amir Shroufi, Radha Rajasingham, David Boulware, Nelesh P. Govender, Angela Loyse
Publikováno v:
Southern African Journal of HIV Medicine, Vol 22, Iss 1, Pp e1-e5 (2021)
The World Health Organization (WHO) has published a guideline for the management of individuals with advanced HIV disease (AHD) to reduce HIV-related deaths. The guideline consists of a package of recommendations including interventions to prevent, d
Externí odkaz:
https://doaj.org/article/87a85555ee614a06828db5589cb870be