Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Joseph O. Nwankwo"'
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 12, Pp 2311-2319 (2003)
Fatty acid delta-6-desaturase (FADS2) is the rate-limiting enzyme in mammalian synthesis of long-chain polyunsaturated fatty acids. We investigated the molecular mechanism of FADS2 deficiency in skin fibroblasts from a patient deficient in this enzym
Externí odkaz:
https://doaj.org/article/aecf5df0e6cd40cfbafe06913499b0d8
Autor:
Deborah E. Williard, Joseph O. Nwankwo, Terry L. Kaduce, Shawn D. Harmon, Mira Irons, Hugo W. Moser, Gerald V. Raymond, Arthur A. Spector
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 4, Pp 501-508 (2001)
Polyunsaturated fatty acid (PUFA) utilization was investigated in skin fibroblasts cultured from a female patient with an inherited abnormality in lipid metabolism. These deficient human skin fibroblasts (DF) converted 85–95% less [1-14C]linoleic a
Externí odkaz:
https://doaj.org/article/098e851cd49b4f2e816301dcf16873e2
Autor:
Stephen O. Okori, Chukwunonso E.C.C. Ejike, Azubuike P. Ebokaiwe, Sharon O. Osawe, Joseph O. Nwankwo
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology
Selenium nanoparticles (SeNPs) are well reported to exhibit pharmacological activities both in vitro and in vivo. However, literature is devoid of studies on the impact of SeNPs and/or metformin (M) against streptozotocin (STZ)-mediated oxidative bra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ff1f34f69df12ae6e3981921ac59465
http://europepmc.org/articles/PMC7561705
http://europepmc.org/articles/PMC7561705
Autor:
Chibuike C. Udenigwe, Faith L. Okoro, Kento Imai, Lu Sun, SO Elom, Ruth T. Boachie, Joseph O. Nwankwo, Chukwunonso E.C.C. Ejike
Publikováno v:
Journal of food biochemistryREFERENCES. 43(12)
In silico and in vitro parameters were used to assess the potential of pigeon pea (Cajanus cajan) nutrient reservoir proteins as sources of dipeptidyl peptidase (DPP)-4 inhibitors. In silico, 40 pigeon pea proteins evaluated had 46% of amino acids as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3c68acb1f5cab57d3fb8fa71a21c4cc
https://pubmed.ncbi.nlm.nih.gov/31576595
https://pubmed.ncbi.nlm.nih.gov/31576595
Autor:
Joseph O. Nwankwo
Publikováno v:
Advances in Cancer Prevention.
A selected number of potential anticancer agents in phytochemicals isolated from some indigenous food and medicinal plants of the West African sub-region, has been reviewed. The attempt has benefited from a store of knowledge on the characterized and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bd3810e36e7cea2b1317b1d4e2f80f5
https://doi.org/10.4172/2472-0429.1000124
https://doi.org/10.4172/2472-0429.1000124
Autor:
Q. Ping Dou, Boris Cvek, Richard Arkwright, Rahul Deshmukh, Joseph O. Nwankwo, Pershang Farshi, Jinbao Liu
Publikováno v:
Expert Opinion on Therapeutic Patents
Introduction Deubiquitinating-enzymes (DUBs) are key components of the ubiquitin-proteasome system (UPS). The fundamental role of DUBs is specific removal of ubiquitin from substrates. DUBs contribute to activation/deactivation, recycling and localiz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90ed83e0c41233475d8979536ea4fd94
https://doi.org/10.1517/13543776.2015.1056737
https://doi.org/10.1517/13543776.2015.1056737
Autor:
Joseph O. Nwankwo, Kebe E. Obeten, Sharoon Griffin, Cornelia M. Keck, Omamuyovwi M. Ijomone, Azubuike P. Ebokaiwe, Richard C. Ehiri, Chukwunonso E.C.C. Ejike
Publikováno v:
PharmaNutrition. 9:100150
The investigation of potential health benefits of nano-sized nutriceuticals is recently a major scientific interest. The present study investigated the effect of Selenium and Loranthus micranthus leaves nanoparticles (SeNPs and LMLNPs), on streptozot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c48b722ba99f408edfb0932faf760dc
https://doi.org/10.1016/j.phanu.2019.100150
https://doi.org/10.1016/j.phanu.2019.100150
Autor:
Joseph O. Nwankwo
Publikováno v:
Medical Hypotheses. 68:661-669
Previous work has established the existence of a co-ordinate response in induction between Phase I xenobiotic metabolism, cytochrome P450 (CYP) and the multidrug resistance (MDR1) genes in hepatocytes and some tumor cells. Further correlation was obt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::508e91de2a85e9c9b8a7884a079a0a36
https://doi.org/10.1016/j.mehy.2006.07.042
https://doi.org/10.1016/j.mehy.2006.07.042
Publikováno v:
Oral Oncology. 38:281-290
Oral cancer is a significant health problem, particularly among individuals that ingest alcohol in combination with the use of tobacco products. The enhanced development of tobacco-initiated oral cancers by ethanol suggests that ethanol or one of its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87afb07727aa90c6b4939cfd620cc0e7
https://doi.org/10.1016/s1368-8375(01)00056-2
https://doi.org/10.1016/s1368-8375(01)00056-2
Autor:
Hugo W. Moser, Mira Irons, Joseph O. Nwankwo, Gerald V. Raymond, Shawn D. Harmon, Arthur A. Spector, Deborah E. Williard, Terry L. Kaduce
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 4, Pp 501-508 (2001)
Polyunsaturated fatty acid (PUFA) utilization was investigated in skin fibroblasts cultured from a female patient with an inherited abnormality in lipid metabolism. These deficient human skin fibroblasts (DF) converted 85–95% less [1-14C]linoleic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ff5cc1871f5fc7947d1bdd3e2092acf
https://doi.org/10.1016/s0022-2275(20)31158-5
https://doi.org/10.1016/s0022-2275(20)31158-5