Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Joseph O. Adebayo"'
Autor:
Ahmed A. Ishola, Joseph O. Adebayo, Isabela P. Ceravolo, Habibu Tijjani, Edson S. Bento, Henrique F. Goulart, Alessandre C. Crispim, Elizabeth A. Balogun, Antonio E. G. Santana, Antoniana U. Krettli
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: Emergence of drug resistant strains of Plasmodium species has necessitated the search for novel antimalarials with unique mechanisms of action. Synthesis of hybrid compounds has been one approach to tackling this challenge. In this stud
Externí odkaz:
https://doaj.org/article/d09927ecdfa44f9f8511ce1e6efa8961
Autor:
Habibu Tijjani, Adegbenro P. Adegunloye, Auwalu Uba, Joseph O. Adebayo, Gideon A. Gyebi, Ibrahim M. Ibrahim
Publikováno v:
Clinical Phytoscience, Vol 8, Iss 1, Pp 1-15 (2022)
Highlights • Flavonoids displayed varying affinities for PLpro and 3CLpro of SARS-CoV-2 • They interacted via hydrogen and non-hydrogen bonds; nine and twenty-seven flavonoids had better binding affinities for PLpro and 3CLpro respectively than l
Externí odkaz:
https://doaj.org/article/0b24ee5c3ccc4b068b6477398ec5bb6f
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Malaria is an endemic disease that affected 229 million people and caused 409 thousand deaths, in 2019. Disease control is based on early diagnosis and specific treatment with antimalarial drugs since no effective vaccines are commercially available
Externí odkaz:
https://doaj.org/article/660249a3747c4bb0bf9f50c05c5ccbbc
Autor:
Gideon A. Gyebi, Oludare M. Ogunyemi, Ibrahim M. Ibrahim, Saheed O. Afolabi, Rotimi J. Ojo, Uju D.I. Ejike, Joseph O. Adebayo
Publikováno v:
Egyptian Journal of Basic and Applied Sciences. 9:588-608
Publikováno v:
Comparative Clinical Pathology. 31:155-168
Autor:
GO Omotoso, Joseph O. Adebayo, Olayemi Joseph Olajide, I. T. Gbadamosi, Bamidele Victor Owoyele, BU Enaibe, Oluwole B. Akinola
Publikováno v:
NIgerian Journal of Neuroscience. 11:53-61
Cuprizone neurotoxicity is commonly induced to mimic demyelinating disorders of the central nervous system, especially multiple sclerosis. This study assessed the role of kolaviron, a Garcinia kola biflavonoid, in restoring behavioural functions in c
Autor:
Oludare M. Ogunyemi, Charles O. Olaiya, Joseph O. Adebayo, Ibrahim M. Ibrahim, Modupe M. Fabusiwa, Joshua O. Ocheje, Gideon A. Gyebi
Publikováno v:
RSC advances. 11(53)
Despite the development of COVID-19 vaccines, at present, there is still no approved antiviral drug against the pandemic. The SARS-CoV-2 3-chymotrypsin-like proteases (S-3CLpro) and papain-like protease (S-PLpro) are essential for the viral prolifera
Autor:
Joseph O. Adebayo, Ibrahim M. Ibrahim, Gideon A. Gyebi, Oludare M. Ogunyemi, Saheed O. Afolabi
The high morbidity and mortality rate of Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2) infection arises majorly from the Acute Respiratory Distress Syndrome and “cytokine storm” syndrome, which is sustained by an aberrant systemic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6606bc91d6078cfffdf462a735ff08a
https://doi.org/10.21203/rs.3.rs-329239/v1
https://doi.org/10.21203/rs.3.rs-329239/v1
Autor:
Modupe M. Fabusiwa, Oludare M. Ogunyemi, Adegbenro P. Adegunloye, Charles O. Olaiya, Gideon A. Gyebi, Abdo A. Elfiky, Joseph O. Adebayo, Ibrahim M. Ibrahim, Joshua O. Ocheje
Publikováno v:
Computers in Biology and Medicine
Antiviral culinary plants are potential bioresources for preventive nutraceuticals and/or antiviral drugs in COVID-19. Structure-based virtual screening was undertaken to screen 173 compounds previously reported from Vernonia amygdalina and Occinum g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3ef74e29db3bcf003529efb8657ca28
https://doi.org/10.21203/rs.3.rs-301445/v1
https://doi.org/10.21203/rs.3.rs-301445/v1
Publikováno v:
SN Applied Sciences. 2
This study employed in vitro and in silico techniques to screen isolated pregnane phytochemicals (P1–P4), as well as their source pregnane-rich chromatographic fractions, which were derived from Gongronema latifolium Benth (GLB), for their inhibito