Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Joseph N. Ciarelli"'
Autor:
Kelly M. Bakulski, Muraly Puttabyatappa, Nadia Saadat, Venkateswaran Ramamoorthi Elangovan, Vasantha Padmanabhan, Robert C. Thompson, John F. Dou, Joseph N. Ciarelli
Publikováno v:
Endocrinology
Prenatal testosterone (T)-treated female sheep manifest peripheral insulin resistance, ectopic lipid accumulation, and insulin signaling disruption in liver and muscle. This study investigated transcriptional changes and transcriptome signature of pr
Publikováno v:
Journal of the Endocrine Society
Prenatal exposure to excess testosterone (T) programs peripheral insulin resistance and dyslipidemia along with tissue-specific increases in ectopic lipid accumulation, oxidative stress and insulin resistance in liver and muscle of the early adult fe
Publikováno v:
Journal of the Endocrine Society
Prenatal testosterone excess induces insulin resistance, dyslipidemia and cardiovascular defects in ewes. Considering adipose depots influence systemic metabolic status, disruptions in visceral (VAT), subcutaneous (SAT), pericardiac (PCAT) and perire
Autor:
Muraly Puttabyatappa, Vasantha Padmanabhan, Kanakadurga Singer, Adam G. Chatoff, Joseph N. Ciarelli
Publikováno v:
Mol Cell Endocrinol
Prenatal testosterone (T)-treated female sheep exhibit an enhanced inflammatory and oxidative stress state in the visceral adipose tissue (VAT) but not in the subcutaneous (SAT), while surprisingly maintaining insulin sensitivity in both depots. In a
Autor:
Richard W. Lieberman, Vasantha Padmanabhan, Muraly Puttabyatappa, Angela S Kelley, Joseph N. Ciarelli, Lixia Zeng, Yolanda R. Smith, Subramaniam Pennathur
Publikováno v:
Endocrinology
Polycystic ovary syndrome (PCOS) is a common condition of reproductive-aged women. In a well-validated sheep model of PCOS, testosterone (T) treatment of pregnant ewes culminated in placental insufficiency and intrauterine growth restriction of offsp
Publikováno v:
Journal of the Endocrine Society
Developmental exposure to endocrine disruptor bisphenol A (BPA) is associated \with metabolic defects during adulthood in the female sheep. These are characterized by peripheral insulin resistance and increase in negative mediators of insulin sensiti