Zobrazeno 1 - 10
of 225
pro vyhledávání: '"Joseph Molnár"'
Autor:
Annamária Kincses, Stefánia Szabó, Bálint Rácz, Nikoletta Szemerédi, Genki Watanabe, Ryosuke Saijo, Hiroshi Sekiya, Eiji Tamai, Joseph Molnár, Masami Kawase, Gabriella Spengler
Publikováno v:
Antibiotics, Vol 9, Iss 10, p 649 (2020)
Bacteria often show resistance against antibiotics due to various mechanisms such as the expression of efflux pumps, biofilm formation, or bacterial quorum sensing (QS) controls. For successful therapy, the discovery of alternative agents is crucial.
Externí odkaz:
https://doaj.org/article/e4e096c52f7847f1a8051a62c19f7b3f
Publikováno v:
Molecules, Vol 25, Iss 7, p 1654 (2020)
Multidrug resistance (MDR) that occurs in cancer cells constitutes one of the major reasons for chemotherapy failure. The main molecular mechanism of MDR is overexpression of protein transporters from the ATP-binding cassette (ABC) superfamily, such
Externí odkaz:
https://doaj.org/article/ed476e311eee48a7855e962b7b458180
Autor:
István Zupkó, Judit Molnár, Borbála Réthy, Renáta Minorics, Éva Frank, János Wölfling, Joseph Molnár, Imre Ocsovszki, Zeki Topcu, Tamás Bitó, László G. Puskás
Publikováno v:
Molecules, Vol 19, Iss 2, Pp 2061-2076 (2014)
A set of solanidine analogs with antiproliferative properties were recently synthetized from pregnadienolone acetate, which occurs in Nature. The aim of the present study was an in vitro characterization of their antiproliferative action and an inves
Externí odkaz:
https://doaj.org/article/962af3f2a8104a8ba0eaf8d0afc937b5
Autor:
Fabian Lentz, Norbert Reiling, Gabriella Spengler, Annamária Kincses, Andrea Csonka, Joseph Molnár, Andreas Hilgeroth
Publikováno v:
Molecules, Vol 24, Iss 16, p 2873 (2019)
The number of effective antituberculotic drugs is strongly limited to four first-line drugs in standard therapy. In case of resistances second-line antibiotics are used with a poor efficacy and tolerability. Therefore, novel antituberculotic drugs ar
Externí odkaz:
https://doaj.org/article/5032db61fee24eb28df6f569b2beed01
Publikováno v:
Molecules, Vol 23, Iss 4, p 825 (2018)
The number of effective first-line antibiotics for the treatment of Mycobacterium tuberculosis infection is strongly limited to a few drugs. Due to emerging resistance against those drugs, second- and third-line antibiotics have been established in t
Externí odkaz:
https://doaj.org/article/c5cd6e2748594dbfaac4e223faeef203
Publikováno v:
Molecules, Vol 22, Iss 2, p 199 (2017)
P-glycoprotein (P-gp, ABCB1) over-expression, causing a multi-drug resistant (MDR) phenotype, is a major problem in cancer chemotherapy that urgently requires novel approaches. Our previous studies showed certain ecdysteroid derivatives as promising
Externí odkaz:
https://doaj.org/article/934ac7a80b634a07bcbbf590f41f9896
Autor:
Mujeeb-ur-Rehman, Mohamed Fawzy Ramadan, Diana Szabo, Ákos Csonka, Abdur Rauf, Joseph Molnár, Muslim Raza, Sami Bawazeer, Mohammad S. Mubarak, Yahia N. Mabkhot, Seema Patel, Salim S. Al-Showiman, Somia Gul, Gokhan Zengin
Publikováno v:
Russian Journal of Bioorganic Chemistry. 47:997-1003
Pistacia integerrima grows in some areas of Pakistan and some other south Asian countries such as Afghanistan, India, Nepal, and Myanmar. It is an important medicinal plant which has been traditionally used for the treatment of asthma, cough, and dys
Autor:
Ákos Csonka, Abdur Rauf, Bina S. Siddiqui, Mudyawati Kamaruddin, Saud Bawazeer, Mohammad S. Mubarak, Mohamed A. El-Esawi, DI罭A Szab Haroon Khan, Md. Habibur Rahman, Eman Elsharkawy, Taibi Ben Hadda, Seema Patel, Muslim Raza, Joseph Molnár, Anees Ahmed Khalil, Ghias Uddin
Publikováno v:
BIOCELL. 45:139-147
Autor:
Hiroshi Sekiya, Borisz Varga, Gabriella Spengler, Bálint Rácz, Jun Maki, Joseph Molnár, Ryosuke Saijo, Genki Watanabe, Masami Kawase, Eiji Tamai, Annamária Kincses
Publikováno v:
Anticancer Research. 38:6181-6187
Background/aim Multidrug resistance (MDR) represents a significant impediment to successful cancer treatment. In this study, novel metal [Zn(II), Cu(II), Mg(II), Ni(II), Pd(II), and Ag(I)] complexes of 2-trifluoroacetonylbenzoxazole previously synthe
Autor:
Joseph Molnár, Beatrix Szalontai, El Mokhtar Essassi, Fouad Ouazzani Chahdi, Gabriella Spengler, Selma Bourichi, Márió Gajdács, Houria Misbahi, Youssef Kandri Rodi, Stefánia Szabo
Publikováno v:
Anticancer Research. 38:3999-4003
BACKGROUND/AIM Malignant diseases present a significant public health burden worldwide and their treatment is further complicated by the phenomenon of multidrug resistance. Derivatives of imidazopyridine exhibit several remarkable pharmacological act