Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Joseph Menassa"'
Autor:
Dimuthu Angage, Jill Chmielewski, Janesha C. Maddumage, Eva Hesping, Sabrina Caiazzo, Keng Heng Lai, Lee Ming Yeoh, Joseph Menassa, D. Herbert Opi, Callum Cairns, Hamsa Puthalakath, James G. Beeson, Marc Kvansakul, Justin A. Boddey, Danny W. Wilson, Robin F. Anders, Michael Foley
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Apical membrane antigen-1 (AMA1) is a conserved malarial vaccine candidate essential for the formation of tight junctions with the rhoptry neck protein (RON) complex, enabling Plasmodium parasites to invade human erythrocytes, hepatocytes, a
Externí odkaz:
https://doaj.org/article/a3ab2a2651db4279a00df14289569c0e
Publikováno v:
Cell Stress, Vol 4, Iss 12, Pp 270-272 (2020)
Sepsis and its impact on human health can be traced back to 1000 BC and continues to be a major health burden today. It causes about 11 million deaths world-wide of which, more than a third are due to neonatal sepsis. There is no effective treatment
Externí odkaz:
https://doaj.org/article/2f049d1f16024aad8edbb64f93536f85
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Sepsis is one of the leading causes of deaths world-wide and yet there are no therapies available other than ICU treatment. The patient outcome is determined by a complex interplay between the pro and anti-inflammatory responses of the body i.e., a h
Externí odkaz:
https://doaj.org/article/17a7e36e27da4d66bfa5b04dc09e7126
Autor:
Marcel Doerflinger, Mubing Duan, Harinda Rajapaksha, Hamsa Puthalakath, Marco J Herold, Chuanxin Liu, Mark D. Hulett, Weisan Chen, Andrew J. Kueh, Thanh Kha Phan, Joseph Menassa, Pierre Faou, Pamali Fonseka, Christina Nedeva
Publikováno v:
Nature Immunology. 21:1585-1596
Sepsis is a biphasic disease characterized by an acute inflammatory response, followed by a prolonged immunosuppressive phase. Therapies aimed at controlling inflammation help to reduce the time patients with sepsis spend in intensive care units, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3565bfe46f2a182a07ce4cbc8d4d9246
https://doi.org/10.1038/s41590-020-0789-z
https://doi.org/10.1038/s41590-020-0789-z
Autor:
Irvin Jose, Ashley Mansell, Liana Mackiewicz, Boris Reljic, Richard S. Hotchkiss, Hamsa Puthalakath, Joseph Menassa, Christina Nedeva, Pierre Faou, Marc Pellegrini, Marcel Doerflinger
Publikováno v:
The FEBS Journal. 288:1809-1821
Sepsis remains to be a major contributor to mortality in ICUs, and immune suppression caused by immune cell apoptosis determines the overall patient survival. However, diagnosis of sepsis-induced lymphopenia remains problematic with no accurate progn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::844e25c577ee800b7f7e36514066f8f6
https://doi.org/10.1111/febs.15552
https://doi.org/10.1111/febs.15552
Autor:
Francine Ke, Jason Glab, Andrew H. Wei, Tao G. Nelson, Samara Naim, Christina Nedeva, Suresh Mathivanan, Hamsa Puthalakath, Lorraine A. O'Reilly, Cody C. Allison, Robert G. Ramsay, Fiona C. Brown, Marcel Doerflinger, Brian J. Smith, Daniel Bachmann, Joseph Menassa, Rahul Srivastava, Yuniel Fernández-Marrero, Lahiru Gangoda, Sanjay Shahi, Andrew J. Kueh, Tatiana Rabachini, Zhipeng Cao, Thomas Kaufmann, Laura D. Osellame
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance It is believed that the Bcl-2 family protein Bok has a redundant role similar to Bax and Bak in regulating apoptosis. We report that this protein interacts with the key enzyme involved in uridine biosynthesis, uridine monophosphate synth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c94d8ec59a137e8d6b83349b667f53d4
Publikováno v:
Cell Stress, Vol 4, Iss 12, Pp 270-272 (2020)
Cell Stress
Cell Stress
Sepsis and its impact on human health can be traced back to 1000 BC and continues to be a major health burden today. It causes about 11 million deaths world-wide of which, more than a third are due to neonatal sepsis. There is no effective treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd310bb8a1704f933a369912a2bde704
Autor:
Christina, Nedeva, Joseph, Menassa, Mubing, Duan, Chuanxin, Liu, Marcel, Doerflinger, Andrew J, Kueh, Marco J, Herold, Pamali, Fonseka, Thanh Kha, Phan, Pierre, Faou, Harinda, Rajapaksha, Weisan, Chen, Mark D, Hulett, Hamsa, Puthalakath
Publikováno v:
Nature immunology. 21(12)
Sepsis is a biphasic disease characterized by an acute inflammatory response, followed by a prolonged immunosuppressive phase. Therapies aimed at controlling inflammation help to reduce the time patients with sepsis spend in intensive care units, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::91f7e98609b38ce2a2c043955f5095a2
https://pubmed.ncbi.nlm.nih.gov/33336149
https://pubmed.ncbi.nlm.nih.gov/33336149