Zobrazeno 1 - 10
of 274
pro vyhledávání: '"Joseph Makhema"'
Autor:
Wonderful T. Choga, Gobuiwang Khilly Kurusa (Gasenna), James Emmanuel San, Tidimalo Ookame, Irene Gobe, Mohammed Chand, Badisa Phafane, Kedumetse Seru, Patience Matshosi, Boitumelo Zuze, Nokuthula Ndlovu, Teko Matsuru, Dorcas Maruapula, Ontlametse T. Bareng, Kutlo Macheke, Lesego Kuate-Lere, Labapotswe Tlale, Onalethata Lesetedi, Modiri Tau, Mpaphi B. Mbulawa, Pamela Smith-Lawrence, Mogomotsi Matshaba, Roger Shapiro, Joseph Makhema, Darren P. Martin, Tulio de Oliveira, Richard J. Lessells, Shahin Lockman, Simani Gaseitsiwe, Sikhulile Moyo
Publikováno v:
International Journal of Infectious Diseases, Vol 138, Iss , Pp 91-96 (2024)
We investigated intra-host genetic evolution using two SARS-CoV-2 isolates from a fully vaccinated (primary schedule x2 doses of AstraZeneca plus a booster of Pfizer), >70-year-old woman with a history of lymphoma and hypertension who presented a SAR
Externí odkaz:
https://doaj.org/article/a4563b67ede2463ca061c016f76e974e
Autor:
Kabo Baruti, Bonolo B. Phinius, Basetsana Phakedi, Gorata Mpebe, Wonderful Choga, Lynnette Bhebhe, Graceful Mulenga, Natasha O. Moraka, Tsholofelo Ratsoma, Molly Pretorius-Holme, Joseph Makhema, Roger Shapiro, Shahin Lockman, Sikhulile Moyo, Mosimanegape Jongman, Motswedi Anderson, Simani Gaseitsiwe
Publikováno v:
Journal of Infection and Public Health, Vol 16, Iss 11, Pp 1736-1741 (2023)
Background: Approximately 15–20 million people worldwide are infected with hepatitis delta virus (HDV), which is approximately 5 % of people with chronic hepatitis B virus (HBV). Sub-Saharan Africa has high HDV prevalence, leading to worse clinical
Externí odkaz:
https://doaj.org/article/dd66fdf5db2c49a28d573a6c8fee0b9e
Autor:
Bonolo B. Phinius, Wonderful T. Choga, Motswedi Anderson, Margaret Mokomane, Irene Gobe, Tsholofelo Ratsoma, Basetsana Phakedi, Gorata Mpebe, Lynnette Bhebhe, Tendani Gaolathe, Mosepele Mosepele, Joseph Makhema, Roger Shapiro, Shahin Lockman, Rosemary Musonda, Sikhulile Moyo, Simani Gaseitsiwe
Publikováno v:
Biomedicines, Vol 12, Iss 7, p 1561 (2024)
(1) Background: Hepatitis B virus (HBV) sequencing data are important for monitoring HBV evolution. We aimed to molecularly characterize HBV sequences from participants with HBV surface antigen-positive (HBsAg+) serology and occult hepatitis B infect
Externí odkaz:
https://doaj.org/article/6829cfe2e45447ae99c2e3fcd79459a4
Autor:
Motswedi Anderson, Thabo Mangogola, Bonolo B. Phinius, Gorata Mpebe, Christopher O. Aimakhu, Wonderful T. Choga, Basetsana Phakedi, Lynnette N. Bhebhe, Doreen Ditshwanelo, Kabo Baruti, Linda Mpofu-Dobo, Lebogang Othusitse, Tsholofelo Ratsoma, Tendani Gaolathe, Joseph Makhema, Roger Shapiro, Shahin Lockman, Sikhulile Moyo, Simani Gaseitsiwe
Publikováno v:
Microorganisms, Vol 12, Iss 6, p 1207 (2024)
(1) Background: we determined the prevalence of the hepatitis B virus (HBV) amongst people without human immunodeficiency virus (HIV) in rural and peri-urban areas in Botswana. (2) Methods: We screened for the hepatitis B surface antigen (HBsAg) from
Externí odkaz:
https://doaj.org/article/ea3db4e9939c447982af0187a751846f
Autor:
Ontlametse T. Bareng, Sikhulile Moyo, Mbatshi Mudanga, Kagiso Sebina, Catherine K. Koofhethile, Wonderful T. Choga, Natasha O. Moraka, Dorcas Maruapula, Irene Gobe, Modisa S. Motswaledi, Rosemary Musonda, Bornapate Nkomo, Dinah Ramaabya, Tony Chebani, Penny Makuruetsa, Joseph Makhema, Roger Shapiro, Shahin Lockman, Simani Gaseitsiwe
Publikováno v:
Viruses, Vol 16, Iss 5, p 720 (2024)
We evaluated subsequent virologic outcomes in individuals experiencing low-level virem ia (LLV) on dolutegravir (DTG)-based first-line antiretroviral therapy (ART) in Botswana. We used a national dataset from 50,742 adults who initiated on DTG-based
Externí odkaz:
https://doaj.org/article/9a9fbac7f29e4b949b9064b7914cbad8
Autor:
Wonderful T. Choga, Samantha L. Letsholo, Chandapiwa Marobela‐Raborokgwe, Irene Gobe, Mbatshi Mazwiduma, Dorcas Maruapula, John Rukwava, Mary Gorettie Binta, Boitumelo J. L Zuze, Legodile Koopile, Kedumetse Seru, Patience Motshosi, Ontlametse Thato Bareng, Botshelo Radibe, Pamela Smith‐Lawrence, Kutlo Macheke, Lesego Kuate‐Lere, Modisa S. Motswaledi, Mpaphi B. Mbulawa, Mogomotsi Matshaba, Kereng V. Masupu, Shahin Lockman, Roger Shapiro, Joseph Makhema, Mosepele Mosepele, Simani Gaseitsiwe, Sikhulile Moyo
Publikováno v:
Veterinary Medicine and Science, Vol 9, Iss 4, Pp 1465-1472 (2023)
Abstract We sought to investigate whether SARS‐CoV‐2 was present, and to perform full‐length genomic sequencing, in a 5‐year‐old male crossbreed dog from Gaborone, Botswana that presented overt clinical signs (flu‐like symptoms, dry hacki
Externí odkaz:
https://doaj.org/article/92e2601e0fa74b2cb40aab8c50df3dee
Autor:
Maureen Sakoi-Mosetlhi, Gbolahan Ajibola, Roxanna Haghighat, Oganne Batlang, Kenneth Maswabi, Molly Pretorius-Holme, Kathleen M Powis, Shahin Lockman, Joseph Makhema, Mathias Litcherfeld, Daniel R Kuritzkes, Roger Shapiro
Publikováno v:
PLoS ONE, Vol 19, Iss 3, p e0299942 (2024)
IntroductionMonthly intravenous infusion of broadly neutralizing monoclonal antibodies may be an attractive alternative to daily oral antiretroviral treatment for children living with HIV. However, acceptability among caregivers remains unknown.Metho
Externí odkaz:
https://doaj.org/article/65c270a1506149dfb1d3093e11593302
Autor:
Boitumelo J. L. Zuze, Botshelo T. Radibe, Wonderful T. Choga, Ontlametse T. Bareng, Natasha O. Moraka, Dorcas Maruapula, Kedumetse Seru, Patrick Mokgethi, Baitshepi Mokaleng, Nokuthula Ndlovu, Nametso Kelentse, Molly Pretorius-Holme, Roger Shapiro, Shahin Lockman, Joseph Makhema, Vlad Novitsky, Kaelo K. Seatla, Sikhulile Moyo, Simani Gaseitsiwe
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACT There are limited data on the prevalence of fostemsavir (FTR) resistance-associated polymorphisms in people with HIV in Botswana. We sought to determine the prevalence of FTR resistance-associated polymorphisms in HIV-1 subtype C sequences f
Externí odkaz:
https://doaj.org/article/8a3484c8f0984aef98f28951e867c1e8
Autor:
Bonolo B. Phinius, Motswedi Anderson, Irene Gobe, Margaret Mokomane, Wonderful T. Choga, Basetsana Phakedi, Tsholofelo Ratsoma, Gorata Mpebe, Joseph Makhema, Roger Shapiro, Shahin Lockman, Rosemary Musonda, Sikhulile Moyo, Simani Gaseitsiwe
Publikováno v:
Viruses, Vol 16, Iss 4, p 592 (2024)
(1) Background: We aimed to determine the prevalence of hepatitis B virus (HBV) resistance-associated mutations (RAMs) in people with HBV and human immunodeficiency virus (HBV/HIV) in Botswana. (2) Methods: We sequenced HBV deoxyribonucleic acid (DNA
Externí odkaz:
https://doaj.org/article/f9f6def8a3cb4e2ea72ab82ff9739613
Autor:
Globahan Ajibola, Charlotte Mdluli, Kara Bennett, Maureen Sakoi, Oganne Batlang, Joseph Makhema, Shahin Lockman, Roger Shapiro, Landon Myer, Kathleen Powis
Publikováno v:
Southern African Journal of HIV Medicine, Vol 24, Iss 1, Pp e1-e6 (2023)
Background: Limited data exist on the differential risk of HIV acquisition between infants born preterm versus those born at term to women living with HIV (WLHIV). With a reported increase in preterm delivery among pregnant WLHIV, understanding the r
Externí odkaz:
https://doaj.org/article/5b17981302a94bda83a8ae64787034aa