Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Joseph M. Ziegelbauer"'
Autor:
Ramya Ramaswami, Takanobu Tagawa, Guruswamy Mahesh, Anna Serquina, Vishal Koparde, Kathryn Lurain, Sarah Dremel, Xiaofan Li, Ameera Mungale, Alex Beran, Zoe Weaver Ohler, Laura Bassel, Andrew Warner, Ralph Mangusan, Anaida Widell, Irene Ekwede, Laurie T. Krug, Thomas S. Uldrick, Robert Yarchoan, Joseph M. Ziegelbauer
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Background Kaposi sarcoma (KS) is a multicentric tumor caused by Kaposi sarcoma herpesvirus (KSHV) that leads to morbidity and mortality among people with HIV worldwide. KS commonly involves the skin but can occur in the gastrointestinal tra
Externí odkaz:
https://doaj.org/article/639afd67b40546c0b88cc5c6da7a379f
Publikováno v:
Algorithms for Molecular Biology, Vol 15, Iss 1, Pp 1-10 (2020)
Abstract Background Data about herpesvirus microRNA motifs on human circular RNAs suggested the following statistical question. Consider independent random counts, not necessarily identically distributed. Conditioned on the sum, decide whether one of
Externí odkaz:
https://doaj.org/article/5c9312ef5abb48d0b5c42fb964ed5b18
Publikováno v:
mBio, Vol 12, Iss 6 (2021)
ABSTRACT Oncogenic gammaherpesviruses express viral products during latent and lytic infection that block the innate immune response. Previously, we found that Kaposi’s sarcoma herpesvirus (KSHV/human herpesvirus-8) viral microRNAs (miRNAs) downreg
Externí odkaz:
https://doaj.org/article/88bfe8a4eb5c4ee19c2daee837ae1461
Autor:
Takanobu Tagawa, Daniel Oh, Jerico Santos, Sarah Dremel, Guruswamy Mahesh, Thomas S. Uldrick, Robert Yarchoan, Vishal N. Kopardé, Joseph M. Ziegelbauer
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Multiple herpesviruses have been recently found to encode viral circular RNAs. Like cellular circular RNAs, these RNAs lack poly-A tails and their 5′ and 3′ ends have been joined, which confers protection from RNA exonucleases. We examined the ex
Externí odkaz:
https://doaj.org/article/0578a920b582409b9f9878c6a737618e
Autor:
David A. Davis, Prabha Shrestha, Ashley I. Aisabor, Alexandra Stream, Veronica Galli, Cynthia A. Pise-Masison, Takanobu Tagawa, Joseph M. Ziegelbauer, Genoveffa Franchini, Robert Yarchoan
Publikováno v:
OncoImmunology, Vol 8, Iss 2 (2019)
Most chronic viruses evade T-cell and natural killer (NK) immunity through downregulation of immune surface markers. Previously we showed that Pomalidomide (Pom) increases surface expression of major histocompatibility complex class I (MHC-I) in Kapo
Externí odkaz:
https://doaj.org/article/3b54caad2b274dc6beb81bd9087a3fae
Publikováno v:
mBio, Vol 8, Iss 4 (2017)
ABSTRACT From various screens, we found that Kaposi’s sarcoma-associated herpesvirus (KSHV) viral microRNAs (miRNAs) target several enzymes in the mevalonate/cholesterol pathway. 3-Hydroxy-3-methylglutaryl-coenzyme A (CoA) synthase 1 (HMGCS1), 3-hy
Externí odkaz:
https://doaj.org/article/a1e2a028c0de4e12a4fc246649afdc23
Publikováno v:
Viruses, Vol 4, Iss 9, Pp 1687-1710 (2012)
EBV and KSHV are both gamma-herpesviruses which express multiple viral microRNAs. Various methods have been used to investigate the functions of these microRNAs, largely through identification of microRNA target genes. Surprisingly, these related vir
Externí odkaz:
https://doaj.org/article/f3d17ac8bbc7421683bbbffbd0740f49
Autor:
Takanobu Tagawa, Daniel Oh, Sarah Dremel, Guruswamy Mahesh, Vishal N. Koparde, Gerard Duncan, Thorkell Andresson, Joseph M. Ziegelbauer
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Non-coding RNAs (ncRNAs) play important roles in host-pathogen interactions; oncogenic viruses like Kaposi’s sarcoma herpesvirus (KSHV) employ ncRNAs to establish a latent reservoir and persist for the life of the host. We previously reported that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4afe2bc65f63d62a7857598dc31874e
https://doi.org/10.1073/pnas.2212864120
https://doi.org/10.1073/pnas.2212864120
Autor:
Coralie Viollet, David A Davis, Shewit S Tekeste, Martin Reczko, Joseph M Ziegelbauer, Francesco Pezzella, Jiannis Ragoussis, Robert Yarchoan
Publikováno v:
PLoS Pathogens, Vol 13, Iss 1, p e1006143 (2017)
Kaposi sarcoma-associated herpesvirus (KSHV) causes several tumors and hyperproliferative disorders. Hypoxia and hypoxia-inducible factors (HIFs) activate latent and lytic KSHV genes, and several KSHV proteins increase the cellular levels of HIF. Her
Externí odkaz:
https://doaj.org/article/db961d63d9b04db5ada9d1a58a70013e
Autor:
Takanobu Tagawa, Daniel Oh, Sarah Dremel, Guruswamy Mahesh, Vishal N. Koparde, Gerard Duncan, Thorkell Andresson, Joseph M. Ziegelbauer
Non-coding RNAs (ncRNAs) play important roles in host-pathogen interactions; oncogenic viruses like Kaposi sarcoma herpesvirus (KSHV) employ ncRNAs to establish a latent reservoir and persist for the life of the host. We previously reported that KSHV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfe498d773a21678d5f43193bb770a15
https://doi.org/10.1101/2022.07.18.500467
https://doi.org/10.1101/2022.07.18.500467
