Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Joseph M. Verdi"'
Autor:
George N. Nikopoulos, Tamara L. Adams, Derek Adams, Leif Oxburgh, Igor Prudovsky, Joseph M. Verdi
Publikováno v:
BioTechniques, Vol 44, Iss 4, Pp 547-549 (2008)
Cellular interactions in development of the kidney are used as a model of reciprocal inductive events between epithelium and mesenchyme. Time- and labor-intensive methods have been developed to study this phenomenon. For example, in mice, the targete
Externí odkaz:
https://doaj.org/article/480d13e5372b48baa4db7d2a5a0bcedd
Autor:
Jennifer A Rochira, Nicholas N Matluk, Tamara L Adams, Aldona A Karaczyn, Leif Oxburgh, Samuel T Hess, Joseph M Verdi
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e20659 (2011)
In normal growth and development, apoptosis is necessary to shape the central nervous system and to eliminate excess neurons which are not required for innervation. In some diseases, however, apoptosis can be either overactive as in some neurodegener
Externí odkaz:
https://doaj.org/article/e75b801b00aa4b13829319f0bcb43348
Publikováno v:
Advances in Bioscience and Biotechnology. :1206-1213
Non-canonical bone morphogenic protein (BMP) pathway signaling plays a critical role during embryonic neurogenesis, inducing apoptosis and eliminating an excess of neural progenitor cells, in preparation for the population of the neural stem cell nic
Autor:
Joseph M. Verdi, Tamara L. Adams
Publikováno v:
Advances in Bioscience and Biotechnology. :567-573
Investigating neural stem cell plasticity in the hippo-campal niche, we demonstrate that retroviral forced expression of Mash1 (Mammalian Achaete-Scute Homolog 1), Olig1(Oligodendrocyte transcription factor 1), and Olig2 (Oligodendrocyte transcriptio
Autor:
Maria F. Duarte, Joseph M. Verdi, Igor Prudovsky, George N. Nikopoulos, Thomas Maciag, Robert Friesel, Chris J. Kubu, Stephen Bellum
Publikováno v:
Stem Cells. 25:3133-3142
The activation of Notch signaling in neural crest stem cells (NCSCs) results in the rapid loss of neurogenic potential and differentiation into glia. We now show that the attenuation of endogenous Notch signaling within expanding NCSC clones by the N
Autor:
Teodora Nicola, Leif Oxburgh, Barbara A. Conley, Maria Cecilia Mancini, Douglas B. Spicer, Calvin P.H. Vary, Joseph M. Verdi
Publikováno v:
Developmental Biology. 308:520-533
Genetic studies show that TGFbeta signaling is essential for vascular development, although the mechanism through which this pathway operates is incompletely understood. Here we demonstrate that the TGFbeta auxiliary coreceptor endoglin (eng, CD105)
Autor:
Daniel P. Moore, George N. Nikopoulos, Stephen Bellum, Calvin P.H. Vary, Joseph M. Verdi, Stephen E. Kendall, Chris J. Kubu, Rebecca A. Cowling, Mahmud Bani-Yaghoub
Publikováno v:
Development. 131:4287-4298
Reports of non-neural differentiation of neural stem cells (NSCs) have been challenged by alternative explanations for expanded differentiation potentials. In an attempt to demonstrate the plasticity of NSC, neurospheres were generated from single re
Publikováno v:
Molecular Biology Reports. 30:15-25
The signaling adapter proteins FRS2 and FRS3 are implicated in the transmission of extracellular signals from nerve growth factor (NGF) or fibroblast growth factor (FGF) receptors to the Ras/mitogen-activated protein kinase signaling cascade. This st
Autor:
Ward A. Pedersen, Lilanie A. Abdur-Rahman, Sic L. Chan, Joseph M. Verdi, Haiyan Zhu, Mark P. Mattson
Publikováno v:
Journal of Neurochemistry. 82:976-986
The development of the nervous system is regulated by trophic signals that control cell proliferation, differentiation, and survival. Numb is an evolutionarily conserved protein identified by its ability to control cell fate in the nervous system of
Autor:
Joseph M. Verdi, Chris J. Kubu, Kenji Orimoto, David J. Anderson, Sean J. Morrison, Gerry Weinmaster
Publikováno v:
Developmental Biology. 244:199-214
Neural stem cells become progressively less neurogenic and more gliogenic with development. Here, we show that between E10.5 and E14.5, neural crest stem cells (NCSCs) become increasingly sensitive to the Notch ligand Delta-Fc, a progliogenic and ant