Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Joseph M. Sweeney"'
Autor:
Hyun ah Yoon, Rachel Bartash, Inessa Gendlina, Johanna Rivera, Antonio Nakouzi, Robert H. Bortz III, Ariel S. Wirchnianski, Monika Paroder, Karen Fehn, Leana Serrano-Rahman, Rachelle Babb, Uzma N. Sarwar, Denise Haslwanter, Ethan Laudermilch, Catalina Florez, M. Eugenia Dieterle, Rohit K. Jangra, J. Maximilian Fels, Karen Tong, Margarette C. Mariano, Olivia Vergnolle, George I. Georgiev, Natalia G. Herrera, Ryan J. Malonis, Jose A. Quiroz, Nicholas C. Morano, Gregory J. Krause, Joseph M. Sweeney, Kelsie Cowman, Stephanie Allen, Jayabhargav Annam, Ariella Applebaum, Daniel Barboto, Ahmed Khokhar, Brianna J. Lally, Audrey Lee, Max Lee, Avinash Malaviya, Reise Sample, Xiuyi A. Yang, Yang Li, Rafael Ruiz, Raja Thota, Jason Barnhill, Doctor Y. Goldstein, Joan Uehlinger, Scott J. Garforth, Steven C. Almo, Jonathan R. Lai, Morayma Reyes Gil, Amy S. Fox, Kartik Chandran, Tao Wang, Johanna P. Daily, Liise-anne Pirofski
Publikováno v:
JCI Insight, Vol 6, Iss 4 (2021)
Convalescent plasma with severe acute respiratory disease coronavirus 2 (SARS-CoV-2) antibodies (CCP) may hold promise as a treatment for coronavirus disease 2019 (COVID-19). We compared the mortality and clinical outcome of patients with COVID-19 wh
Externí odkaz:
https://doaj.org/article/0358cbc15a254f3fab654810aaab2594
Autor:
Joseph M. Sweeney, Mohammad Barouqa, Gregory J. Krause, Jesus D. Gonzalez-Lugo, Shafia Rahman, Morayma Reyes Gil
Publikováno v:
TH Open, Vol 05, Iss 01, Pp e89-e103 (2021)
The causes of coagulopathy associated with coronavirus disease 2019 (COVID-19) are poorly understood. We aimed to investigate the relationship between von Willebrand factor (VWF) biomarkers, intravascular hemolysis, coagulation, and organ damage in C
Externí odkaz:
https://doaj.org/article/feaf5bece3944db8864d637c9451297b
Autor:
Martin Kaczocha, Yuchen Zhou, Joyce Che, Hao-Chi Hsu, Iwao Ojima, Dale G. Deutsch, Olivia M. Joseph, Robert C. Rizzo, Matthew W. Elmes, Joseph M. Sweeney, Huilin Li
Publikováno v:
Biochemistry
Fatty acid binding protein 5 (FABP5) is a promising target for development of inhibitors to help control pain and inflammation. In this work, computer-based docking (DOCK6 program) was employed to screen ∼2 M commercially available compounds to FAB
Autor:
Keith M. Studholme, Joyce Che, Joseph M. Sweeney, Christopher J. Giuliano, Olivia M. Joseph, Lauren E. Prentis, Matthew W. Elmes, Steven E. Glynn, Gregory Carbonetti, Dale G. Deutsch, Robert C. Rizzo, Luke L. McGoldrick, Martin Kaczocha
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
The increasing use of medical marijuana highlights the importance of developing a better understanding of cannabinoid metabolism. Phytocannabinoids, including ∆9-tetrahydrocannabinol (THC), are metabolized and inactivated by cytochrome P450 enzymes
Autor:
Mohammad Barouqa, Jesus D. Gonzalez-Lugo, Joseph M. Sweeney, Morayma Reyes Gil, Gregory J. Krause, Shafia Rahman
Publikováno v:
TH Open, Vol 05, Iss 01, Pp e89-e103 (2021)
TH Open: Companion Journal to Thrombosis and Haemostasis
American Journal of Clinical Pathology
TH Open: Companion Journal to Thrombosis and Haemostasis
American Journal of Clinical Pathology
Systemic inflammation and coagulopathy are characteristic hallmarks of COVID19. “COVID coagulopathy” manifests mainly as a prothrombotic state affecting both large and small blood vessels, and presenting as arterial, venous, and microangiopathic
Autor:
Iwao Ojima, Matthew W. Elmes, Monaf Awwa, Joseph M. Sweeney, Martin Kaczocha, Jerome Falcone, Simon Tong, Yunrong Jing, Diane Bogdan, Brian P. Ralph, Dale G. Deutsch, Joyce Che, Longfei Wei, Gregory Carbonetti, Robert C. Rizzo, Liqun Wang, Norbert Smietalo, Huilin Li, Yuchen Zhou, Kongzhen Hu, Timothy Clement, Matthew Freitag, Olivia M. Joseph, Qianwen Gan, Hao-Chi Hsu, Su Yan, Gary Y.H. Teng
Publikováno v:
European Journal of Medicinal Chemistry. 154:233-252
Fatty acid binding proteins (FABPs) serve as critical modulators of endocannabinoid signaling by facilitating the intracellular transport of anandamide and whose inhibition potentiates anandamide signaling. Our previous work has identified a novel sm
Autor:
Matthew W, Elmes, Lauren E, Prentis, Luke L, McGoldrick, Christopher J, Giuliano, Joseph M, Sweeney, Olivia M, Joseph, Joyce, Che, Gregory S, Carbonetti, Keith, Studholme, Dale G, Deutsch, Robert C, Rizzo, Steven E, Glynn, Martin, Kaczocha
Publikováno v:
Scientific Reports
The increasing use of medical marijuana highlights the importance of developing a better understanding of cannabinoid metabolism. Phytocannabinoids, including ∆9-tetrahydrocannabinol (THC), are metabolized and inactivated by cytochrome P450 enzymes
Publikováno v:
Lipids. 53(3)
Lipocalin-type prostaglandin D synthase (L-PGDS; EC:5.3.99.2) is an enzyme with dual functional roles as a prostaglandin D(2)-synthesizing enzyme and as an extracellular transporter for diverse lipophilic compounds in the cerebrospinal fluid (CSF). T
Autor:
William T. Berger, Dale G. Deutsch, Martin Kaczocha, Jeremy T. Miyauchi, Iwao Ojima, Stella E. Tsirka, KwanNok Leung, Brian P. Ralph, Joseph M. Sweeney, Liqun Wang, Matthew W. Elmes
Publikováno v:
The Journal of biological chemistry. 290(14)
Δ(9)-Tetrahydrocannabinol (THC) and cannabidiol (CBD) occur naturally in marijuana (Cannabis) and may be formulated, individually or in combination in pharmaceuticals such as Marinol or Sativex. Although it is known that these hydrophobic compounds
Autor:
Joseph M. Sweeney
Publikováno v:
The American Journal of Comparative Law. 13:145-156