Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Joseph M. Seroogy"'
Autor:
Lisa Alaimo, Mukund Mehrotra, Mark S. Smyth, Joseph M. Seroogy, Gerd Ruhter, Jack W. Rose, Gary Park, Julie Anne Heath, Deborah Volkots, Theo Schotten, Robert M. Scarborough, Anjali Pandey
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 12:1103-1107
The synthesis and biological activity of analogues containing spiro piperidinylpyridine and pyrrolidinylpyridine templates are described. The potent activity of these compounds as platelet aggregation inhibitors demonstrates the utility of the spiro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a15d464cd411ab812697d7726beff49a
https://doi.org/10.1016/s0960-894x(02)00095-1
https://doi.org/10.1016/s0960-894x(02)00095-1
Autor:
Anjali Pandey, Theo Schotten, Joseph M. Seroogy, Julie Anne Heath, Deborah Volkots, Gerd Ruhter, Mukund Mehrotra, Jack W. Rose, Robert M. Scarborough, Mark S. Smyth
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 11:1293-1296
The synthesis and biological activity of novel glycoprotein IIb–IIIa anatagonists containing 3-azaspiro[5.5]undec-9-yl nucleus are described. The potent activity of these compounds as platelet aggregation inhibitors demonstrates the utility of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b18b0062b238c9d17a8337d2dc7e8c61
https://doi.org/10.1016/s0960-894x(01)00216-5
https://doi.org/10.1016/s0960-894x(01)00216-5
Autor:
Mukund Mehrotra, Robert M. Scarborough, Gary L. Park, Deborah Volkots, Jack W. Rose, Joseph L. Lambing, Anjali Pandey, Julie Anne Heath, Joseph M. Seroogy, Stanley J. Hollenbach, Mark S. Smyth, Lisa Nannizzi-Alaimo
Publikováno v:
Journal of medicinal chemistry. 47(8)
In our efforts to develop orally active GPIIb-IIIa antagonists with improved pharmaceutical properties, we have utilized a novel 2,8-diazaspiro[4.5]decane scaffold as a template. We describe here our investigation of a variety of templates including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b5204cd6f8ac6564f5791a45cba87ec
https://pubmed.ncbi.nlm.nih.gov/15056002
https://pubmed.ncbi.nlm.nih.gov/15056002
Autor:
Jack W. Rose, Deborah Volkots, Athiwat Hutchaleelaha, Keith Abe, Anjali Pandey, Neill A. Giese, Joseph M. Seroogy, Stanley J. Hollenbach, Robert M. Scarborough, Joseph L. Lambing, Jin-Chen Yu
Publikováno v:
Journal of medicinal chemistry. 45(17)
We have previously found that the 4-[4-(N-substituted carbamoyl)-1-piperazinyl]-6,7-dimethoxyquinazolines can function as potent and selective inhibitors of platelet-derived growth factor receptor (PDGFR) phosphorylation. A series of highly potent, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0b046caf1cc450dff642671e744c63a
https://pubmed.ncbi.nlm.nih.gov/12166950
https://pubmed.ncbi.nlm.nih.gov/12166950