Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Joseph M. Schober"'
Publikováno v:
BioTechniques, Vol 73, Iss 6, Pp 273-279 (2022)
There are various approaches in which one can isolate microglia from murine brains, such as immunomagnetic, density gradient, FACS and differential adhesive methods. In this procedure a modified flask-tapping approach was used due to its simplicity a
Externí odkaz:
https://doaj.org/article/9b4c5bab220041aba694c7b244ddab4b
Autor:
Elizabeth R Denn, Joseph M Schober
Publikováno v:
BioTechniques, Vol 70, Iss 5, Pp 278-284 (2021)
Cellular redox changes are common in apoptosis, immune function, signaling pathways and cancer. The authors aimed to develop a single-wavelength method using the superior fluorescence sensitivity of a flow cytometer for measuring redox-sensitive gree
Externí odkaz:
https://doaj.org/article/66a5d590156e467db2982d669c4f03cb
Publikováno v:
ASPET 2023 Annual Meeting Abstract - Cellular and Molecular Pharmacology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7500f01eb6b64b0d6cfc4fdef46a6ff3
https://doi.org/10.1124/jpet.122.523850
https://doi.org/10.1124/jpet.122.523850
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189589 (2017)
IQGAP1 interacts with a number of binding partners through a calponin homology domain (CHD), a WW motif, IQ repeats, a Ras GAP-related domain (GRD), and a conserved C-terminal (CT) domain. Among various biological and cellular functions, IQGAP1 is kn
Externí odkaz:
https://doaj.org/article/379d46e86c394862865892ffcf3bad77
Publikováno v:
Biochemical and Biophysical Research Communications. 448:39-44
IQGAP1 has emerged as a key component in the regulation of cytoskeleton dynamics during cell migration, maintenance of adherens junctions, microbial pathogenesis and intracellular trafficking. IQGAP1 is known to localize to the protruding edge of lam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ca41ef0336859cdae6929ed0f0d9fd7
https://doi.org/10.1016/j.bbrc.2014.04.038
https://doi.org/10.1016/j.bbrc.2014.04.038
Autor:
Anna Akhmanova, Ho Sup Lee, Oana Danciu, Niels Galjart, Steven P. Gygi, Rana Anjum, Joseph M. Schober, Elena S. Nadezhdina, Gary G. Borisy, Yulia Komarova, John Peloquin, Jeffrey van Haren
Publikováno v:
Molecular Biology of the Cell
Molecular Biology of the Cell, 21(15), 2661-2673. American Society for Cell Biology
Molecular Biology of the Cell, 21(15), 2661-2673. American Society for Cell Biology
CLIP-170 conformational changes are regulated by phosphorylation on S309 and S311 residues resulting in diminished binding of CLIP-170 for growing MT ends and p150Glued.
Cytoplasmic linker protein (CLIP)-170 is a microtubule (MT) plus-end-tracki
Cytoplasmic linker protein (CLIP)-170 is a microtubule (MT) plus-end-tracki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c532bf5f0744a775cf877b1559fa0271
http://europepmc.org/articles/PMC2912352
http://europepmc.org/articles/PMC2912352
Autor:
Marileen Dogterom, Srinivas Honnappa, Ilya Grigoriev, Christian O. De Groot, Yulia Komarova, Joseph M. Schober, Anna Akhmanova, Rubén M. Buey, E. Laura Munteanu, Susana Montenegro Gouveia, Casper C. Hoogenraad, Michel O. Steinmetz, Gary G. Borisy
Publikováno v:
Journal of Cell Biology, 184(5), 691-706. Rockefeller University Press
The Journal of Cell Biology
The Journal of cell biology
The Journal of Cell Biology
The Journal of cell biology
End binding proteins (EBs) are highly conserved core components of microtubule plus-end tracking protein networks. Here we investigated the roles of the three mammalian EBs in controlling microtubule dynamics and analyzed the domains involved. Protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b877c09900be90c752d0f649aa2957d6
https://pure.eur.nl/en/publications/ac2ee953-1ad1-4b39-aa6a-9c098b3bdc35
https://pure.eur.nl/en/publications/ac2ee953-1ad1-4b39-aa6a-9c098b3bdc35
Autor:
Joy I.Hsuan Lee, Joseph M. Schober, Sarah Haverlock-Moyns, G. W. Gant Luxton, Gregory A. Smith
Publikováno v:
Journal of Virology. 80:201-209
Transport of capsids in cells is critical to alphaherpesvirus infection and pathogenesis; however, viral factors required for transport have yet to be identified. Here we provide a detailed examination of capsid dynamics during the egress phase of in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f09e93a23067a33494e28c5e5a7f742
https://doi.org/10.1128/jvi.80.1.201-209.2006
https://doi.org/10.1128/jvi.80.1.201-209.2006
Autor:
Eugene E. Emeson, Richard D. Ye, Tatiana P. Ugarova, Igor Jovanovic, Lester F. Lau, Joseph M. Schober, Stephen C.-T. Lam, Ningyu Chen, Tatiana M. Grzeszkiewicz
Publikováno v:
Blood. 99:4457-4465
Cysteine-rich 61 (Cyr61, CCN1) and connective tissue growth factor (CTGF, CCN2) are growth factor-inducible immediate-early gene products found in blood vessel walls and healing cutaneous wounds. We previously reported that the adhesion of endothelia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6d220a93c71e989cae26f0f8c69928f
https://doi.org/10.1182/blood.v99.12.4457
https://doi.org/10.1182/blood.v99.12.4457
Publikováno v:
Cancer letters. 284(1)
Remodeling of actin and microtubule cytoskeletons is thought to be coupled; however, the interplay between these two systems is not fully understood. We show a microtubule end-binding protein, EB1, is required for formation of polarize morphology and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e68609df85dd76e4605fd4531ac782c
https://pubmed.ncbi.nlm.nih.gov/19427113
https://pubmed.ncbi.nlm.nih.gov/19427113