Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Joseph M. Pickard"'
Autor:
Aly A. Khan, Leonid Yurkovetskiy, Kelly O’Grady, Joseph M. Pickard, Renée de Pooter, Dionysios A. Antonopoulos, Tatyana Golovkina, Alexander Chervonsky
Publikováno v:
Cell Reports, Vol 29, Iss 3, Pp 541-550.e4 (2019)
Summary: Environmental influences (infections and diet) strongly affect a host’s microbiota. However, host genetics may influence commensal communities, as suggested by the greater similarity between the microbiomes of identical twins compared to n
Externí odkaz:
https://doaj.org/article/7613ea228e1147c692789bf4f72b422a
Publikováno v:
Nature reviews. Microbiology.
A dense and diverse microbial community inhabits the gut and many epithelial surfaces. Referred to as the microbiota, it co-evolved with the host and is beneficial for many host physiological processes. A major function of these symbiotic microorgani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::169472c8e0198d55fdff8fb86bc3af3a
https://pubmed.ncbi.nlm.nih.gov/36539611
https://pubmed.ncbi.nlm.nih.gov/36539611
Publikováno v:
Curr Opin Microbiol
Citrobacter rodentium is a mouse-specific pathogen commonly used to model infection by human Enteropathogenic Escherichia coli, an important cause of infant diarrhea and mortality worldwide. In the early phase of infection, C. rodentium overcomes com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f6cbffbfe632e54c091989a777bb9a3
https://pubmed.ncbi.nlm.nih.gov/34352594
https://pubmed.ncbi.nlm.nih.gov/34352594
Publikováno v:
Cell hostmicrobe. 28(4)
The microbiota confers host protection by limiting the colonization of pathogenic bacteria in the gut, but the mechanisms by which pathogens overcome colonization resistance remain poorly understood. Using a high-density transposon screen in the ente
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b28aa35ea9331062c305693889ac2594
https://pubmed.ncbi.nlm.nih.gov/33031733
https://pubmed.ncbi.nlm.nih.gov/33031733
Autor:
Sang Uk Seo, Xue Li, Matthew J. Hoostal, Cathryn R. Nagler, Merritt Gillilland, Eric C. Martens, Andrew T. Stefka, Shinji Fukuda, Thomas D. Wang, Yun Gi Kim, Kei Sakamoto, Gabriel Núñez, Thomas M. Schmidt, Taylor Feehley, Joseph M. Pickard, Naohiro Inohara, Nicholas A. Pudlo
Publikováno v:
Science. 356:315-319
Gut anaerobes protect against pathogen invasion Intestinal infections are a common problem for young animals. One explanation is that the protective gut microbiota is not fully established in infants. How the microbiota might protect against pathogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4459f4a6c66f98db6681ee1accfdfd8e
https://doi.org/10.1126/science.aag2029
https://doi.org/10.1126/science.aag2029
Autor:
Joseph M. Pickard, Gabriel Núñez
Publikováno v:
Am J Pathol
Mammals have coevolved with a large community of symbiotic, commensal, and some potentially pathogenic microbes. The trillions of bacteria and hundreds of species in our guts form a relatively stable community that resists invasion by outsiders, incl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fa612db14e35c42d4548164c5b87837
https://pubmed.ncbi.nlm.nih.gov/31100210
https://pubmed.ncbi.nlm.nih.gov/31100210
Publikováno v:
The Journal of Immunology. 194:5588-5593
Fucose is an l-configuration sugar found abundantly in the mammalian gut. It has long been known to be induced there by the presence of bacteria, but only recently have some of the molecular mechanisms behind this process been uncovered. New work sug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70430994b8aa68b6144db0d73869570e
https://doi.org/10.4049/jimmunol.1500395
https://doi.org/10.4049/jimmunol.1500395
Publikováno v:
Cell Host & Microbe. 17(5):548-552
Given the recognized role of the commensal microbiota in regulating host immunity to pathogens, it is not surprising that microbiota are also capable of regulating autoimmune responses. The underlying mechanisms of autoimmune regulation by the microb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74eb247421a2c4cdf8a9a3182b09bb50
The intestinal tract of mammals is colonized by a large number of microorganisms including trillions of bacteria that are referred to collectively as the gut microbiota. These indigenous microorganisms have co-evolved with the host in a symbiotic rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::857958994c65e636b0404967eadf5ffa
https://europepmc.org/articles/PMC5657496/
https://europepmc.org/articles/PMC5657496/
Autor:
Dionysios A. Antonopoulos, Tatyana V. Golovkina, Renée F. de Pooter, Aly A. Khan, Joseph M. Pickard, Leonid Yurkovetskiy, Alexander V. Chervonsky, Kelly O’Grady
Publikováno v:
Cell Reports, Vol 29, Iss 3, Pp 541-550.e4 (2019)
Summary: Environmental influences (infections and diet) strongly affect a host’s microbiota. However, host genetics may influence commensal communities, as suggested by the greater similarity between the microbiomes of identical twins compared to n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::638e3eacd44ea4c6e0c6eeec36f2bd01
https://doi.org/10.1016/j.celrep.2019.09.010
https://doi.org/10.1016/j.celrep.2019.09.010