Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Joseph M. Lasker"'
Publikováno v:
IEEE Transactions on Instrumentation and Measurement. 57:182-189
We introduce a novel digital lock-in detection technique for simultaneously measuring the amplitude and phase of multiple amplitude-modulated signals. Using particular modulation and sampling constraints and averaging filters, we achieve optimal nois
Autor:
Joseph M. Lasker, Mario Löcker, Andreas H. Hielscher, Christoph H. Schmitz, Randall L. Barbour
Publikováno v:
Review of Scientific Instruments. 73:429-439
In this article, we describe the design rationale and performance features of an integrated multichannel continuous wave (cw) near-infrared (NIR) optical tomographic imager capable of collecting fast tomographic measurements over a large dynamic rang
Autor:
Joseph M. Lasker, Alexander D. Klose, Avraham Y. Bluestone, Uwe J. Netz, Andreas H. Hielscher, Jürgen Beuthan, Mark G. Stewart, Gassan S. Abdoulaev
Publikováno v:
Disease Markers, Vol 18, Iss 5-6, Pp 313-337 (2002)
Scopus-Elsevier
Disease Markers
Scopus-Elsevier
Disease Markers
Diffuse optical tomography (DOT) is emerging as a viable new biomedical imaging modality. Using near-infrared (NIR) light, this technique probes absorption as well as scattering properties of biological tissues. First commercial instruments are now a
Publikováno v:
Biomedical Optics.
We performed dynamic imaging studies on healthy volunteers and patients diagnosed with rheumatoid arthritis (RA) in proximal-interphalangeal finger joints. We observed pronounced differences between the hemodynamic effect occurring in healthy volunte
Publikováno v:
EMBC
Digital lock-in detection provides spectroscopic and imaging instruments a means of measuring physical quantities with improved signal to noise ratios compared to analogue detection schemes. We introduce a digital lock-in detection algorithm for meas
Publikováno v:
Diffuse Optical Imaging of Tissue.
Optical probing of hemodynamics is often employed in areas such as brain, muscular, and breast-cancer imaging. In these studies an external stimulus is applied and changes in relevant physiological parameters, e.g. oxy or deoxyhemoglobin concentratio
Publikováno v:
Diffuse Optical Imaging of Tissue.
We describe a new dynamic optical tomography system that is, unlike currently available analog instrumentation, based on digital data-acquisition and filtering techniques. At the heart of this continuous wave instrument is a digital signal processor
Autor:
Joseph M. Lasker, James M. Masciotti, Andreas H. Hielscher, Christoph H. Schmitz, Mathew Schoenecker
Publikováno v:
SPIE Proceedings.
In this paper we present a novel application of digital detection and data-acquisition techniques to a prototype dynamic optical tomography system. The core component is a digital signal processor (DSP) that is responsible for collecting and processi
Publikováno v:
Diffuse Optical Imaging of Tissue.
Publikováno v:
Biomedical Optics.
We evaluated the performance of static and dynamic optical tomographic imaging for characterizing rheumatoid joints. We found that information generated by each approach is complementary and that using both modalities together enhances the diagnostic