Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Joseph M. Gurski"'
Autor:
Andrew X. Zhu, Nabeel Bardeesy, Ryan B. Corcoran, Dejan Juric, Alberto Bardelli, Ralph Tiedt, Diana Graus Porta, Gad Getz, A. John Iafrate, James R. Stone, David P. Ryan, Pascal Furet, Christelle Stamm, Louise Barys, Barbara Schacher-Engstler, Sabrina Baltschukat, Joseph M. Gurski, Emily E. Van Seventer, Jiaoyuan Elisabeth Sun, Laura Henderson, Stephanie Reyes, Benedetta Mussolin, Avinash Kambadakone, Vikram Deshpande, Phuong Vu, Jochen K. Lennerz, Leanne G. Ahronian, Ignaty Leshchiner, Giulia Siravegna, Leah Y. Liu, Supriya K. Saha, Lipika Goyal
Complete Data for Genetic Analysis of ctDNA and Tumor Tissue for All Samples.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::259d7240a0c496326f717ca14ca60e36
https://doi.org/10.1158/2159-8290.22531277.v1
https://doi.org/10.1158/2159-8290.22531277.v1
Autor:
Ryan B. Corcoran, Levi A. Garraway, Jeffrey A. Engelman, A. John Iafrate, Dora Dias-Santagata, Gad Getz, Mari Mino-Kenudson, Tiffany G. Huynh, Niall J. Lennon, Lisa M. Green, Kristin Anderka, Samira Bahl, Joseph M. Gurski, Anuj Kalsy, Elizabeth L. Lockerman, Craig H. Mermel, Kerry D. Lynch, Koki Nishimura, Jason T. Godfrey, Jason E. Faris, Eunice L. Kwak, Nikhil Wagle, Eliezer M. Van Allen, Erin M. Sennott, Leanne G. Ahronian
Supplementary Figure S5. Role of ARAF Q489L and MEK F53L in resistance.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::159b92665530fed33babe57bbb3fb25d
https://doi.org/10.1158/2159-8290.22530041.v1
https://doi.org/10.1158/2159-8290.22530041.v1
Autor:
Ryan B. Corcoran, Levi A. Garraway, Jeffrey A. Engelman, A. John Iafrate, Dora Dias-Santagata, Gad Getz, Mari Mino-Kenudson, Tiffany G. Huynh, Niall J. Lennon, Lisa M. Green, Kristin Anderka, Samira Bahl, Joseph M. Gurski, Anuj Kalsy, Elizabeth L. Lockerman, Craig H. Mermel, Kerry D. Lynch, Koki Nishimura, Jason T. Godfrey, Jason E. Faris, Eunice L. Kwak, Nikhil Wagle, Eliezer M. Van Allen, Erin M. Sennott, Leanne G. Ahronian
Supplementary Table S1. Patient characteristics and MAPK pathway reactivating resistance mechanisms of BRAF-mutant CRC patients with clinical acquired resistance to RAF/EGFR or RAF/MEK inhibitor combinations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68672d23e9c3704897ff3623acae1192
https://doi.org/10.1158/2159-8290.22530038
https://doi.org/10.1158/2159-8290.22530038
Autor:
Ryan B. Corcoran, Levi A. Garraway, Jeffrey A. Engelman, A. John Iafrate, Dora Dias-Santagata, Gad Getz, Mari Mino-Kenudson, Tiffany G. Huynh, Niall J. Lennon, Lisa M. Green, Kristin Anderka, Samira Bahl, Joseph M. Gurski, Anuj Kalsy, Elizabeth L. Lockerman, Craig H. Mermel, Kerry D. Lynch, Koki Nishimura, Jason T. Godfrey, Jason E. Faris, Eunice L. Kwak, Nikhil Wagle, Eliezer M. Van Allen, Erin M. Sennott, Leanne G. Ahronian
Supplementary Table S2. Summary of variant calls from WES analysis of matched pre-treatment and post-progression biopsies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::508ebe7535916250464f6736fff903e5
https://doi.org/10.1158/2159-8290.22530032
https://doi.org/10.1158/2159-8290.22530032
Autor:
Andrew X. Zhu, Nabeel Bardeesy, Ryan B. Corcoran, Dejan Juric, Alberto Bardelli, Ralph Tiedt, Diana Graus Porta, Gad Getz, A. John Iafrate, James R. Stone, David P. Ryan, Pascal Furet, Christelle Stamm, Louise Barys, Barbara Schacher-Engstler, Sabrina Baltschukat, Joseph M. Gurski, Emily E. Van Seventer, Jiaoyuan Elisabeth Sun, Laura Henderson, Stephanie Reyes, Benedetta Mussolin, Avinash Kambadakone, Vikram Deshpande, Phuong Vu, Jochen K. Lennerz, Leanne G. Ahronian, Ignaty Leshchiner, Giulia Siravegna, Leah Y. Liu, Supriya K. Saha, Lipika Goyal
Supplementary Figure S1. Confirmation of secondary point mutation in FGFR2-ZMYM4 allele. Supplementary Figure S2. Homology between FGFR2 and FGFR3 proteins. Supplementary Figure S3. FGFR2-OPTN fusion detected in all autopsy lesions. Supplementary Fig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a948c1840bf99757e3637d1d57bc6518
https://doi.org/10.1158/2159-8290.22531280
https://doi.org/10.1158/2159-8290.22531280
Autor:
Ryan B. Corcoran, Levi A. Garraway, Jeffrey A. Engelman, A. John Iafrate, Dora Dias-Santagata, Gad Getz, Mari Mino-Kenudson, Tiffany G. Huynh, Niall J. Lennon, Lisa M. Green, Kristin Anderka, Samira Bahl, Joseph M. Gurski, Anuj Kalsy, Elizabeth L. Lockerman, Craig H. Mermel, Kerry D. Lynch, Koki Nishimura, Jason T. Godfrey, Jason E. Faris, Eunice L. Kwak, Nikhil Wagle, Eliezer M. Van Allen, Erin M. Sennott, Leanne G. Ahronian
Supplementary Figure S1. KRAS FISH analysis of parental and resistance cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a75becf461b17f10518263a39fea2b15
https://doi.org/10.1158/2159-8290.22530053
https://doi.org/10.1158/2159-8290.22530053
Autor:
Ryan B. Corcoran, Levi A. Garraway, Jeffrey A. Engelman, A. John Iafrate, Dora Dias-Santagata, Gad Getz, Mari Mino-Kenudson, Tiffany G. Huynh, Niall J. Lennon, Lisa M. Green, Kristin Anderka, Samira Bahl, Joseph M. Gurski, Anuj Kalsy, Elizabeth L. Lockerman, Craig H. Mermel, Kerry D. Lynch, Koki Nishimura, Jason T. Godfrey, Jason E. Faris, Eunice L. Kwak, Nikhil Wagle, Eliezer M. Van Allen, Erin M. Sennott, Leanne G. Ahronian
Supplementary Figure S2. KRAS mutation drives resistance to RAF inhibitor combinations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36f9e57f074e6af28b8bf210e87b35fb
https://doi.org/10.1158/2159-8290.22530050
https://doi.org/10.1158/2159-8290.22530050
Autor:
Ryan B. Corcoran, Levi A. Garraway, Jeffrey A. Engelman, A. John Iafrate, Dora Dias-Santagata, Gad Getz, Mari Mino-Kenudson, Tiffany G. Huynh, Niall J. Lennon, Lisa M. Green, Kristin Anderka, Samira Bahl, Joseph M. Gurski, Anuj Kalsy, Elizabeth L. Lockerman, Craig H. Mermel, Kerry D. Lynch, Koki Nishimura, Jason T. Godfrey, Jason E. Faris, Eunice L. Kwak, Nikhil Wagle, Eliezer M. Van Allen, Erin M. Sennott, Leanne G. Ahronian
Supplementary Figure S3. Copy number alterations for Patient #1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e3aa5fa97deb80db2a5be43d4f9f8a9
https://doi.org/10.1158/2159-8290.22530047
https://doi.org/10.1158/2159-8290.22530047
Autor:
Ryan B. Corcoran, Eliezer M. Van Allen, A. John Iafrate, Dora Dias-Santagata, Nicholas A. Jessop, Joseph M. Gurski, Catriona B. Hong, Brandon Nadres, Emily E. Van Seventer, Theodore S. Hong, Janet E. Murphy, Jason E. Faris, Eunice L. Kwak, Jeffrey W. Clark, Jill N. Allen, Aparna R. Parikh, Lifeng Chen, Heather A. Shahzade, Leanne G. Ahronian, David Liu, G. Celine Han, Marianna Kleyman, Mehlika Hazar-Rethinam
Supplementary Figures, Tables, Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84ce7541270ee6481b31d9cc32b0e30e
https://doi.org/10.1158/2159-8290.22532971
https://doi.org/10.1158/2159-8290.22532971
Autor:
Ryan B. Corcoran, Levi A. Garraway, Jeffrey A. Engelman, A. John Iafrate, Dora Dias-Santagata, Gad Getz, Mari Mino-Kenudson, Tiffany G. Huynh, Niall J. Lennon, Lisa M. Green, Kristin Anderka, Samira Bahl, Joseph M. Gurski, Anuj Kalsy, Elizabeth L. Lockerman, Craig H. Mermel, Kerry D. Lynch, Koki Nishimura, Jason T. Godfrey, Jason E. Faris, Eunice L. Kwak, Nikhil Wagle, Eliezer M. Van Allen, Erin M. Sennott, Leanne G. Ahronian
Supplementary Figure S4. Wild-type KRAS overexpression drives resistance to RAF inhibitor combinations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b8ebc146bb6e5c46683f4a20837541b
https://doi.org/10.1158/2159-8290.22530044
https://doi.org/10.1158/2159-8290.22530044