Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Joseph M. Erwin"'
Autor:
Mary Ann eRaghanti, Melissa K. Edler, Richard S. Meindl, Jessica eSudduth, Tatiana eBohush, Joseph M. Erwin, Cheryl D. Stimpson, Patrick R Hof, Chet C Sherwood
Publikováno v:
Frontiers in Human Neuroscience, Vol 8 (2014)
Neuropeptide Y (NPY) plays a role in a variety of basic physiological functions and has also been implicated in regulating cognition, including learning and memory. A decrease in neocortical NPY has been reported for Alzheimer’s disease, schizophre
Externí odkaz:
https://doaj.org/article/dca2b8079f4f4ef9a8783bac89088c11
A comparison of cell density and serotonergic innervation of the amygdala among four macaque species
Publikováno v:
Journal of Comparative Neurology. 529:1659-1668
The genus Macaca is an ideal model for investigating the biological basis of primate social behavior from an evolutionary perspective. A significant amount of behavioral diversity has been reported among the macaque species, but little is known about
Autor:
Patrick R. Hof, M. A. Raghanti, Melissa K. Edler, Elaine E. Guevara, Agnès Lacreuse, Selena S In, Merina Varghese, Joseph M. Erwin, Sophia Raia, Sylvia E. Perez, Elliott J. Mufson, Emily L. Munger, Chet C. Sherwood, Bridget Wicinski, Carmen Freire-Cobo, Maria Medalla, Jennifer I. Luebke, Jessie Laffey
Publikováno v:
Am J Primatol
While humans exhibit a significant degree of neuropathological changes associated with deficits in cognitive and memory functions during aging, nonhuman primates present with more variable expressions of pathological alterations among individuals and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c47e851fa011d46deb813f54ad4da425
https://europepmc.org/articles/PMC8551009/
https://europepmc.org/articles/PMC8551009/
Autor:
Melissa K. Edler, Elliott J. Mufson, Patrick R. Hof, Chet C. Sherwood, Richard S. Meindl, Joseph M. Erwin, Mary Ann Raghanti, John J. Ely, William D. Hopkins, Emily L. Munger
Publikováno v:
Philos Trans R Soc Lond B Biol Sci
In the absence of disease, ageing in the human brain is accompanied by mild cognitive dysfunction, gradual volumetric atrophy, a lack of significant cell loss, moderate neuroinflammation, and an increase in the amyloid beta (A β ) and tau proteins.
Publikováno v:
Prog Neurobiol
We mapped the connections of the insular von Economo neuron (VEN) area in ex vivo brains of a bonobo, an orangutan and two gorillas with high angular resolution diffusion MRI imaging acquired in 36 hour imaging sessions for each brain. The apes died
Autor:
William D. Hopkins, Patrick R. Hof, Melissa K. Edler, Mary Ann Raghanti, Elliott J. Mufson, John J. Ely, Richard S. Meindl, Chet C. Sherwood, Joseph M. Erwin
Publikováno v:
Neurobiology of Aging. 59:107-120
Alzheimer's disease (AD) is a uniquely human brain disorder characterized by the accumulation of amyloid-beta protein (Aβ) into extracellular plaques, neurofibrillary tangles (NFT) made from intracellular, abnormally phosphorylated tau, and selectiv
Autor:
Mary Ann Raghanti, John J. Ely, William D. Hopkins, Lakaléa J. Wilson, Melissa K. Edler, Chet C. Sherwood, Bob Jacobs, Joseph M. Erwin, Patrick R. Hof, Alexa R. Stephenson
Publikováno v:
Journal of Comparative Neurology. 524:2117-2129
The dopaminergic innervation of the striatum has been implicated in learning processes and in the development of human speech and language. Several lines of evidence suggest that evolutionary changes in dopaminergic afferents of the striatum may be a
Autor:
Melissa K. Edler, Daniel P. Perl, Mary Ann Raghanti, John J. Ely, Elliott J. Mufson, Chet C. Sherwood, William D. Hopkins, Richard S. Meindl, Emily L. Munger, Patrick R. Hof, Joseph M. Erwin
In Alzheimer's disease (AD), the brain's primary immune cells, microglia, become activated and are found in close apposition to amyloid beta (Aβ) protein plaques and neurofibrillary tangles (NFT). The present study evaluated microglia density and mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47c96c5caca6b00167ccb409c4bf3f75
https://europepmc.org/articles/PMC6283685/
https://europepmc.org/articles/PMC6283685/
Autor:
Melissa K. Edler, Emily L. Munger, Chet C. Sherwood, Patrick R. Hof, Mary Ann Raghanti, Joseph M. Erwin, John J. Ely, Daniel P. Perl, William D. Hopkins, Elliott J. Mufson
Publikováno v:
J Comp Neurol
Astrocytes are the main homeostatic cell of the central nervous system. In addition, astrocytes mediate an inflammatory response when reactive to injury or disease known as astrogliosis. Astrogliosis is marked by an increased expression of glial fibr