Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Joseph M. Cleary"'
Publikováno v:
eLife, Vol 12 (2024)
GTP-tubulin is preferentially incorporated at growing microtubule ends, but the biochemical mechanism by which the bound nucleotide regulates the strength of tubulin:tubulin interactions is debated. The ‘self-acting’ (cis) model posits that the n
Externí odkaz:
https://doaj.org/article/68fe5f499f9a438da74d307b30dd5768
Publikováno v:
eLife, Vol 11 (2022)
Microtubule polymerization dynamics result from the biochemical interactions of αβ-tubulin with the polymer end, but a quantitative understanding has been challenging to establish. We used interference reflection microscopy to make improved measure
Externí odkaz:
https://doaj.org/article/35dee14dd5b040aab8f8ec633f21dd54
Publikováno v:
bioRxiv
GTP-tubulin is preferentially incorporated at growing microtubule ends, but the biochemical mechanism by which the bound nucleotide regulates the strength of tubulin:tubulin interactions is debated. The ‘self-acting’ (cis) model posits that the n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5632a1ee169303847c6decc38da81405
https://doi.org/10.1101/2023.05.03.539131
https://doi.org/10.1101/2023.05.03.539131
Autor:
William O. Hancock, Joseph M. Cleary
Publikováno v:
Curr Biol
Microtubules are dynamic cytoskeletal filaments composed of αβ-tubulin heterodimers. Historically, the dynamics of single tubulin interactions at the growing microtubule tip have been inferred from steady-state growth kinetics. However, recent adva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8901522d226a98bab4acdd4332c1d5a7
https://doi.org/10.1016/j.cub.2021.02.035
https://doi.org/10.1016/j.cub.2021.02.035
Autor:
Joseph M. Cleary, Chengye Feng, James I. Hertzler, William O. Hancock, Alexis T. Weiner, Melissa M. Rolls, Gregory O. Kothe, Michelle C. Stone
Publikováno v:
J Cell Sci
Axons and dendrites are distinguished by microtubule polarity. In Drosophila, dendrites are dominated by minus-end-out microtubules, whereas axons contain plus-end-out microtubules. Local nucleation in dendrites generates microtubules in both orienta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::691add0bf2b4094ed13717d92c0d053d
https://europepmc.org/articles/PMC8214762/
https://europepmc.org/articles/PMC8214762/
Autor:
Joseph M. Cleary
Publikováno v:
Biophysical Journal. 118:439a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2703fe8b04309b210f9be97ab026328
https://doi.org/10.1016/j.bpj.2019.11.2463
https://doi.org/10.1016/j.bpj.2019.11.2463
Publikováno v:
Journal of the Royal Society, Interface. 15(141)
Contemporary studies have revealed dramatic changes in the diversity of bacterial microbiota between healthy and diseased skin. However, the prevailing use of swabs to extract the microorganisms has meant that only population ‘snapshots’ are obta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b178d33358be6dd720b58880dce55a66
https://pubmed.ncbi.nlm.nih.gov/29669890
https://pubmed.ncbi.nlm.nih.gov/29669890
Autor:
David F.J. Arginteanu, Ana B. Asenjo, Joseph M. Cleary, Yalei Chen, William O. Hancock, Geng-Yuan Chen, Jacob A. Mascaro, Hernando Sosa
Publikováno v:
Curr Biol
Summary Besides sliding apart antiparallel microtubules during spindle elongation, the mitotic kinesin-5, Eg5, promotes microtubule polymerization, emphasizing its importance in mitotic spindle length control. Here, we characterize the Eg5 microtubul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45fa505af2845fc0df557315c9fba31f
https://doi.org/10.1016/j.cub.2019.05.075
https://doi.org/10.1016/j.cub.2019.05.075
Autor:
Joseph M. Cleary
Publikováno v:
Biophysical Journal. 116:255a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14a890d407f39d3844b4d91e590b3702
https://doi.org/10.1016/j.bpj.2018.11.1393
https://doi.org/10.1016/j.bpj.2018.11.1393