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Autor:
Ludek Blaha, Brad L. Upham, Lan Lan Li, Jacob Scott, Joseph M. Carbone, Alisa M. Rummel, Chad Coe, Miodrag Guzvic, James E. Trosko
Publikováno v:
Nutrition and Cancer. 57:38-47
Dicumyl peroxide (di-CuOOH) and benzoyl peroxide (BzOOH) act as tumor promoters in SENCAR mice, whereas di-tert-butylhydroperoxide does not. Tumor promotion requires the removal of growth suppression by inhibition of gap junctional intercellular comm
Autor:
Brad L. Upham, Joseph M. Carbone, James E. Trosko, Yanli Ouyang, Alisa M. Rummel, Robert B. Crawford, Norbert E. Kaminski
Publikováno v:
International Journal of Cancer. 104:12-18
Many tumor promoters suppress the immune system; however, the direct effect of immunosuppressants on the tumorigenic pathways of nonimmune cells in solid tissue has not been well documented. Cannabinoids were chosen to explore this question further.
Publikováno v:
Journal of Urology. 165:1605-1611
Purpose: Pubovaginal sling procedures offer highly effective treatment for patients with female stress urinary incontinence. A recent modification of this technique is the use of cadaveric fascia lata as a sling material supported with titanium ancho
Autor:
Sarki A. Abdulkadir, William J. Catalona, Cathy K. Naughton, Jeffrey Milbrandt, Thomas J. Peters, Jeffrey I. Gordon, Joseph M. Carbone, Emily M. Garabedian, Zhican Qu, Joseph J. H. Ackerman, John Svaren, Sheng-Kwei Song, Peter A. Humphrey
Publikováno v:
Nature Medicine. 7:101-107
The transcription factor early growth response protein 1 (EGR1) is overexpressed in a majority of human prostate cancers and is implicated in the regulation of several genes important for prostate tumor progression. Here we have assessed the effect o
Publikováno v:
Journal of Urologic Pathology. 9:73-82
Publikováno v:
The American Journal of Surgical Pathology. 21:1215-1222
High-grade prostatic intraepithelial neoplasia (HGPIN) is the most likely precursor proliferation of peripheral zone, moderately to poorly differentiated prostatic adenocarcinomas. The usual cell type of the epithelial lining of HGPIN is a glandular
Publikováno v:
Urology. 47:140-142
Pelvic lymphocele is an infrequent complication of pelvic surgery, usually presenting shortly after surgery. We report a case of an infected pelvic lymphocele presenting more than 1 year after a staging pelvic lymphadenectomy for adenocarcinoma of th
Autor:
Joseph M. Carbone, Paramjit S. Chandhoke, Donald A. Urban, Kurt Kerbl, Bernard C. De Leo, Ralph V. Clayman
Publikováno v:
Journal of Urology. 151:686-688
We report a case of percutaneous removal of a staghorn calculus that was accomplished in a morbidly obese patient while he was in a full flank position. In this position, the stone could be successfully accessed and fragmented without compromising th
Autor:
Joseph M. Carbone, Sarki A. Abdulkadir, William J. Catalona, Jeffrey Milbrandt, Peter A. Humphrey, Cathy K. Naughton
Publikováno v:
Human pathology. 32(9)
The transcription factor EGR1 is frequently overexpressed in human prostate cancer and regulates the expression of several genes important for tumor progression. In addition, mice lacking the Egr1 gene show a defect in prostate tumorigenesis. NAB2 is