Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Joseph M. Bateman"'
Autor:
Kriti Shah, Shiyang He, David J. Turner, Joshua Corbo, Khadija Rebbani, Daniel Dominguez, Joseph M. Bateman, Sihem Cheloufi, Cátia Igreja, Eugene Valkov, Jernej Murn
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract How RNA-binding proteins (RBPs) convey regulatory instructions to the core effectors of RNA processing is unclear. Here, we document the existence and functions of a multivalent RBP–effector interface. We show that the effector interface o
Externí odkaz:
https://doaj.org/article/49fd27e15c2542ee9ab82c8f580b2dbf
Autor:
Lucy Granat, Debbra Y. Knorr, Daniel C. Ranson, Ram Prosad Chakrabarty, Navdeep S. Chandel, Joseph M. Bateman
Publikováno v:
Biology Open, Vol 13, Iss 2 (2024)
Externí odkaz:
https://doaj.org/article/46633e0f244a488ab57f783dc16bd03c
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Mechanistic target of rapamycin (mTOR) is a highly conserved serine/threonine kinase that regulates fundamental cellular processes including growth control, autophagy and metabolism. mTOR has key functions in nervous system development and mis-regula
Externí odkaz:
https://doaj.org/article/9586724e1faf49c182f26eb6a2fcc896
Autor:
Elin Vinsland, Pranetha Baskaran, Simeon R. Mihaylov, Carl Hobbs, Hannah Wood, Ihssane Bouybayoune, Kriti Shah, Corinne Houart, Andrew R. Tee, Jernej Murn, Cathy Fernandes, Joseph M. Bateman
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Correct orchestration of nervous system development is a profound challenge that involves coordination of complex molecular and cellular processes. Mechanistic target of rapamycin (mTOR) signaling is a key regulator of nervous system develop
Externí odkaz:
https://doaj.org/article/d680b34dc4ab4a0a8a0923b28ff97310
Autor:
Konstantinos Afratis, Joseph M. Bateman, Benjamin F. Rahemtulla, Oliver Hughes, Benjamin C. Milgram, Thomas A. Mulhern, Eric P. A. Talbot
Publikováno v:
Organic Letters. 25:461-465
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82706862490ae4b8607a9b06a2739107
https://doi.org/10.1021/acs.orglett.2c03889
https://doi.org/10.1021/acs.orglett.2c03889
Autor:
Sheenagh G. Aiken, Joseph M. Bateman, Hsuan-Hung Liao, Alexander Fawcett, Teerawut Bootwicha, Paolo Vincetti, Eddie L. Myers, Adam Noble, Varinder K. Aggarwal
Publikováno v:
Nature Chemistry. 15:248-256
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2dafcdae51969413d78c3cd493777a25
https://doi.org/10.1038/s41557-022-01087-9
https://doi.org/10.1038/s41557-022-01087-9
Autor:
Olivia F Duncan, Lucy Granat, Ramya Ranganathan, Vandana K Singh, David Mazaud, Manolis Fanto, David Chambers, Clive G Ballard, Joseph M Bateman
Publikováno v:
PLoS Genetics, Vol 14, Iss 7, p e1007567 (2018)
Mitochondrial dysfunction activates the mitochondrial retrograde signaling pathway, resulting in large scale changes in gene expression. Mitochondrial retrograde signaling in neurons is poorly understood and whether retrograde signaling contributes t
Externí odkaz:
https://doaj.org/article/6f4f0cf8245141e7b83e7200ec2da95e
Autor:
Lucy Granat, Daniel Ranson, Emma Hamer, Ram Prosad Chakrabarty, Francesca Mattedi, Laura Fort-Aznar, Frank Hirth, Sean T. Sweeney, Alessio Vagnoni, Navdeep S. Chandel, Joseph M. Bateman
Mutations in mitochondrial complex I cause mitochondrial complex I deficiency, a group of severe neurological diseases that can result in death in infancy. The mechanisms underlying complex I deficiency pathogenesis remain poorly understood, and as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::761337e0319c579b6f3418bd2b5a46ad
https://doi.org/10.1101/2022.09.22.509020
https://doi.org/10.1101/2022.09.22.509020
Publikováno v:
Synlett. 32:1236-1240
The stereoselective synthesis of substituted morpholine derivatives has been achieved through a two-step process involving diastereoselective addition of a Grignard reagent to a sulfinyl imine, followed by cyclization.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81d84aa2fc32fe94f50a85574d58abd1
https://doi.org/10.1055/a-1529-4797
https://doi.org/10.1055/a-1529-4797
Autor:
Joseph M, Bateman
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2431
Mitochondria are essential organelles that generate energy and play vital roles in cellular metabolism. The small circular mitochondrial genome encodes key components of the mitochondrial respiratory apparatus. Depletion of, or mutations in mitochond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7b6a4ea5ca07ff5c689c2524bd04178f
https://pubmed.ncbi.nlm.nih.gov/35412289
https://pubmed.ncbi.nlm.nih.gov/35412289