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pro vyhledávání: '"Joseph M Zock"'
Autor:
Joseph M Zock
Publikováno v:
Combinatorial Chemistry & High Throughput Screening
Over the last decade, imaging as a detection mode for cell based assays has opened a new world of opportunities to measure "phenotypic endpoints" in both current and developing biological models. These "high content" methods combine multiple measurem
Autor:
D. Lansing Taylor, R L DeBiasio, Joseph M. Zock, Kenneth A. Giuliano, George N. Pavlakis, Albert Gough, Joanne M. Volosky, R. Terry Dunlay
Publikováno v:
SLAS Discovery. 2:249-259
Recent improvements in target discovery and high throughput screening (HTS) have increased the pressure at key points along the drug discovery pipeline. High-content screening (HCS) was developed t...
Publikováno v:
SLAS Discovery. 2:33-40
Membranes prepared from stable transfected cells expressing the human gene encoding a functional 5-hydroxytryptaminelE (5HT1E) receptor were used to investigate high-affinity [3H]serotonin ([3H]5-HT) binding with scintillation proximity assay (SPA) t