Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Joseph M Replogle"'
Autor:
Joseph M Replogle, Jessica L Bonnar, Angela N Pogson, Christina R Liem, Nolan K Maier, Yufang Ding, Baylee J Russell, Xingren Wang, Kun Leng, Alina Guna, Thomas M Norman, Ryan A Pak, Daniel M Ramos, Michael E Ward, Luke A Gilbert, Martin Kampmann, Jonathan S Weissman, Marco Jost
Publikováno v:
eLife, Vol 11 (2022)
CRISPR interference (CRISPRi) enables programmable, reversible, and titratable repression of gene expression (knockdown) in mammalian cells. Initial CRISPRi-mediated genetic screens have showcased the potential to address basic questions in cell biol
Externí odkaz:
https://doaj.org/article/af03cd98b4f34c128b98cd963fa2ba56
Autor:
Emily D Crawford, Irene Acosta, Vida Ahyong, Erika C Anderson, Shaun Arevalo, Daniel Asarnow, Shannon Axelrod, Patrick Ayscue, Camillia S Azimi, Caleigh M Azumaya, Stefanie Bachl, Iris Bachmutsky, Aparna Bhaduri, Jeremy Bancroft Brown, Joshua Batson, Astrid Behnert, Ryan M Boileau, Saumya R Bollam, Alain R Bonny, David Booth, Michael Jerico B Borja, David Brown, Bryan Buie, Cassandra E Burnett, Lauren E Byrnes, Katelyn A Cabral, Joana P Cabrera, Saharai Caldera, Gabriela Canales, Gloria R Castañeda, Agnes Protacio Chan, Christopher R Chang, Arthur Charles-Orszag, Carly Cheung, Unseng Chio, Eric D Chow, Y Rose Citron, Allison Cohen, Lillian B Cohn, Charles Chiu, Mitchel A Cole, Daniel N Conrad, Angela Constantino, Andrew Cote, Tre'Jon Crayton-Hall, Spyros Darmanis, Angela M Detweiler, Rebekah L Dial, Shen Dong, Elias M Duarte, David Dynerman, Rebecca Egger, Alison Fanton, Stacey M Frumm, Becky Xu Hua Fu, Valentina E Garcia, Julie Garcia, Christina Gladkova, Miriam Goldman, Rafael Gomez-Sjoberg, M Grace Gordon, James C R Grove, Shweta Gupta, Alexis Haddjeri-Hopkins, Pierce Hadley, John Haliburton, Samantha L Hao, George Hartoularos, Nadia Herrera, Melissa Hilberg, Kit Ying E Ho, Nicholas Hoppe, Shayan Hosseinzadeh, Conor J Howard, Jeffrey A Hussmann, Elizabeth Hwang, Danielle Ingebrigtsen, Julia R Jackson, Ziad M Jowhar, Danielle Kain, James Y S Kim, Amy Kistler, Oriana Kreutzfeld, Jessie Kulsuptrakul, Andrew F Kung, Charles Langelier, Matthew T Laurie, Lena Lee, Kun Leng, Kristoffer E Leon, Manuel D Leonetti, Sophia R Levan, Sam Li, Aileen W Li, Jamin Liu, Heidi S Lubin, Amy Lyden, Jennifer Mann, Sabrina Mann, Gorica Margulis, Diana M Marquez, Bryan P Marsh, Calla Martyn, Elizabeth E McCarthy, Aaron McGeever, Alexander F Merriman, Lauren K Meyer, Steve Miller, Megan K Moore, Cody T Mowery, Tanzila Mukhtar, Lusajo L Mwakibete, Noelle Narez, Norma F Neff, Lindsay A Osso, Diter Oviedo, Suping Peng, Maira Phelps, Kiet Phong, Peter Picard, Lindsey M Pieper, Neha Pincha, Angela Oliveira Pisco, Angela Pogson, Sergei Pourmal, Robert R Puccinelli, Andreas S Puschnik, Elze Rackaityte, Preethi Raghavan, Madhura Raghavan, James Reese, Joseph M Replogle, Hanna Retallack, Helen Reyes, Donald Rose, Marci F Rosenberg, Estella Sanchez-Guerrero, Sydney M Sattler, Laura Savy, Stephanie K See, Kristin K Sellers, Paula Hayakawa Serpa, Maureen Sheehy, Jonathan Sheu, Sukrit Silas, Jessica A Streithorst, Jack Strickland, Doug Stryke, Sara Sunshine, Peter Suslow, Renaldo Sutanto, Serena Tamura, Michelle Tan, Jiongyi Tan, Alice Tang, Cristina M Tato, Jack C Taylor, Iliana Tenvooren, Erin M Thompson, Edward C Thornborrow, Eric Tse, Tony Tung, Marc L Turner, Victoria S Turner, Rigney E Turnham, Mary J Turocy, Trisha V Vaidyanathan, Ilia D Vainchtein, Manu Vanaerschot, Sara E Vazquez, Anica M Wandler, Anne Wapniarski, James T Webber, Zara Y Weinberg, Alexandra Westbrook, Allison W Wong, Emily Wong, Gajus Worthington, Fang Xie, Albert Xu, Terrina Yamamoto, Ying Yang, Fauna Yarza, Yefim Zaltsman, Tina Zheng, Joseph L DeRisi
Publikováno v:
PLoS Pathogens, Vol 16, Iss 10, p e1008966 (2020)
Externí odkaz:
https://doaj.org/article/3bbb68a359bd42bc9db996dc6d89e140
Autor:
Max A Horlbeck, Lea B Witkowsky, Benjamin Guglielmi, Joseph M Replogle, Luke A Gilbert, Jacqueline E Villalta, Sharon E Torigoe, Robert Tjian, Jonathan S Weissman
Publikováno v:
eLife, Vol 5 (2016)
The prokaryotic CRISPR (clustered regularly interspaced palindromic repeats)-associated protein, Cas9, has been widely adopted as a tool for editing, imaging, and regulating eukaryotic genomes. However, our understanding of how to select single-guide
Externí odkaz:
https://doaj.org/article/0b04a6d7357c482dbd1342412af468f4
Autor:
Angela N Pogson, Jessica L Bonnar, Joseph M Replogle, Christina R Liem, Nolan K Maier, Yufang Ding, Baylee J Russell, Xingren Wang, Kun Leng, Alina Guna, Thomas M Norman, Ryan A Pak, Daniel M Ramos, Michael E Ward, Luke A Gilbert, Martin Kampmann, Jonathan S Weissman, Marco Jost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e7d2d97d229edac14829d4e3858e296
https://doi.org/10.7554/elife.81856.sa2
https://doi.org/10.7554/elife.81856.sa2
Autor:
Alina Guna, Taylor A. Stevens, Alison J. Inglis, Joseph M. Replogle, Theodore K. Esantsi, Gayathri Muthukumar, Kelly C. L. Shaffer, Maxine L. Wang, Angela N. Pogson, Jeff J. Jones, Brett Lomenick, Tsui-Fen Chou, Jonathan S. Weissman, Rebecca M. Voorhees
Publikováno v:
Science (New York, N.Y.). 378(6617)
In the mitochondrial outer membrane, tail-anchored (TA) proteins play critical roles in cytoplasmic-mitochondrial communication. Using genome-wide CRISPRi screens, we identify factors involved in mitochondrial TA biogenesis in human cells. We show th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8bf1c0e463a28b3a74f91ec606281a0
https://pubmed.ncbi.nlm.nih.gov/36264797
https://pubmed.ncbi.nlm.nih.gov/36264797
Autor:
Luke W. Koblan, Britt Adamson, Albert Xu, Mandana Arbab, Tyler A Sisley, Jordan L. Doman, Dian Yang, Joseph M. Replogle, David R. Liu, Andrew V. Anzalone, Jeffrey A. Hussmann, Max W. Shen, Gregory A. Newby, Beverly Mok, Jonathan S. Weissman
Publikováno v:
Nature Biotechnology. 39:1414-1425
Programmable C•G-to-G•C base editors (CGBEs) have broad scientific and therapeutic potential, but their editing outcomes have proved difficult to predict and their editing efficiency and product purity are often low. We describe a suite of engine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::794631ca2dbb8219581743d613b4016c
https://doi.org/10.1038/s41587-021-00938-z
https://doi.org/10.1038/s41587-021-00938-z
Autor:
Peggy P. Hsu, Brian T. Do, Sidney Y. Vermeulen, Zhishan Wang, Taghreed Hirz, Najihah Aziz, Joseph M. Replogle, Keene L. Abbott, Samuel Block, Alicia M. Darnell, Raphael Ferreira, Jelena Milosevic, Daniel R. Schmidt, Christopher Chidley, Xiaofeng A. Su, Isaac S. Harris, Jonathan S. Weissman, Sihem Cheloufi, David B. Sykes, Matthew G. Vander Heiden
Control of cellular identity involves coordination of developmental programs with environmental factors such as nutrient availability, suggesting that modulating aspects of metabolism could enable therapeutically relevant changes in cell fate. We sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::658375c9602937b8290e1739b7d0b09c
https://doi.org/10.1101/2022.08.16.503984
https://doi.org/10.1101/2022.08.16.503984
Autor:
Sara Sunshine, Andreas S. Puschnik, Joseph M. Replogle, Matthew T. Laurie, Jamin Liu, Beth Shoshana Zha, James K. Nuñez, Janie R. Byrum, Aidan H. McMorrow, Matthew B. Frieman, Juliane Winkler, Xiaojie Qiu, Oren S. Rosenberg, Manuel D. Leonetti, Chun Jimmie Ye, Jonathan S. Weissman, Joseph L. DeRisi, Marco Y. Hein
Numerous host factors of SARS-CoV-2 have been identified by screening approaches, but delineating their molecular roles during infection and whether they can be targeted for antiviral intervention remains a challenge. Here we use Perturb-seq, a singl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbaa94ef2f29976676b7ef1a47db5cc9
https://doi.org/10.1101/2022.07.15.500120
https://doi.org/10.1101/2022.07.15.500120
Autor:
Joseph M. Replogle, Jessica L. Bonnar, Angela N. Pogson, Christina R. Liem, Nolan K. Maier, Yufang Ding, Baylee J. Russell, Xingren Wang, Kun Leng, Alina Guna, Thomas M. Norman, Ryan A. Pak, Daniel M. Ramos, Michael E. Ward, Luke A. Gilbert, Martin Kampmann, Jonathan S. Weissman, Marco Jost
CRISPR interference (CRISPRi) enables programmable, reversible, and titratable repression of gene expression (knockdown) in mammalian cells. Initial CRISPRi-mediated genetic screens have showcased the potential to address basic questions in cell biol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fdf7ca55256386579b422055fd4e823
https://doi.org/10.1101/2022.07.13.499814
https://doi.org/10.1101/2022.07.13.499814
Autor:
Iain C. Clark, Kristina M. Fontanez, Robert H. Meltzer, Yi Xue, Corey Hayford, Aaron May-Zhang, Chris D’Amato, Ahmad Osman, Jesse Q. Zhang, Pabodha Hettige, Jacob S. A. Ishibashi, Cyrille L. Delley, Daniel W. Weisgerber, Joseph M. Replogle, Marco Jost, Kiet T. Phong, Vanessa E. Kennedy, Cheryl A. C. Peretz, Esther A. Kim, Siyou Song, William Karlon, Jonathan S. Weissman, Catherine C. Smith, Zev J. Gartner, Adam R. Abate
Single-cell RNA sequencing is now a standard method used to reveal the molecular details of cellular heterogeneity, but current approaches have limitations on speed, scale, and ease of use that stem from the complex microfluidic devices or fluid hand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c89d7e7b508bf784cc90a1a421a67d6a
https://doi.org/10.1101/2022.06.10.495582
https://doi.org/10.1101/2022.06.10.495582