Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Joseph M Lewis"'
Autor:
Fabrice E. Graf, Richard N. Goodman, Sarah Gallichan, Sally Forrest, Esther Picton-Barlow, Alice J. Fraser, Minh-Duy Phan, Madalitso Mphasa, Alasdair T. M. Hubbard, Patrick Musicha, Mark A. Schembri, Adam P. Roberts, Thomas Edwards, Joseph M. Lewis, Nicholas A. Feasey
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Infections with Enterobacterales (E) are increasingly difficult to treat due to antimicrobial resistance. After ceftriaxone replaced chloramphenicol (CHL) as empiric therapy for suspected sepsis in Malawi in 2004, extended-spectrum beta-lact
Externí odkaz:
https://doaj.org/article/a653d1fed48c4d248ed8875692a5b104
Autor:
Joseph M Lewis, Richard S Savage, Nicholas J Beeching, Mike B J Beadsworth, Nicholas Feasey, James A Covington
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0188879 (2017)
OBJECTIVES:New point of care diagnostics are urgently needed to reduce the over-prescription of antimicrobials for bacterial respiratory tract infection (RTI). We performed a pilot cross sectional study to assess the feasibility of gas-capillary colu
Externí odkaz:
https://doaj.org/article/21eacbb5fd134abb82a0406031481503
Autor:
Gavin Ackers-Johnson, Ralfh Pulmones, Danielle McLaughlan, Amy Doyle, Joseph M. Lewis, Tim Neal, Stacy Todd, Adam P. Roberts
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 12 (2024)
ABSTRACT Healthcare-associated infections (HAIs) are a significant burden to health systems, with antimicrobial resistance (AMR) further compounding the issue. The hospital environment plays a significant role in the development of HAIs, with microbi
Externí odkaz:
https://doaj.org/article/75bc3e0ccaeb40de8dc2ad6b0b5892f0
Autor:
Eva Heinz, Oliver Pearse, Allan Zuza, Sithembile Bilima, Chisomo Msefula, Patrick Musicha, Patriciah Siyabu, Edith Tewesa, Fabrice E. Graf, Rebecca Lester, Samantha Lissauer, Jennifer Cornick, Joseph M. Lewis, Kondwani Kawaza, Nicholas R. Thomson, Nicholas A. Feasey
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-17 (2024)
Abstract Background Infections caused by multidrug-resistant gram-negative bacteria present a severe threat to global public health. The WHO defines drug-resistant Klebsiella pneumoniae as a priority pathogen for which alternative treatments are need
Externí odkaz:
https://doaj.org/article/389b70344adb4c468575cb18c6a2d66d
Autor:
Yussif Alhassan, Lilian Otiso, Linet Okoth, Lois Murray, Charlotte Hemingway, Joseph M. Lewis, Mandela Oguche, Vicki Doyle, Nelly Muturi, Emily Ogwang, Hellen C. Barsosio, Miriam Taegtmeyer
Publikováno v:
BMC Pregnancy and Childbirth, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Early attendance at antenatal care (ANC), coupled with good-quality care, is essential for improving maternal and child health outcomes. However, achieving these outcomes in sub-Saharan Africa remains a challenge. This study exami
Externí odkaz:
https://doaj.org/article/6ce8baeb82164e789925745621b87771
Publikováno v:
Critical Care, Vol 23, Iss 1, Pp 1-11 (2019)
Abstract Background Aetiology and outcomes of sepsis in sub-Saharan Africa (sSA) are poorly described; we performed a systematic review and meta-analysis to summarise the available data. Methods Systematic searches of PubMed and Scopus were undertake
Externí odkaz:
https://doaj.org/article/7f7c5e280335485599334a62bfe8a22c
Publikováno v:
Wellcome Open Research, Vol 4 (2020)
Background: Extended-spectrum beta-lactamase producing Enterobacteriaceae (ESBL-E) threaten human health; and, in areas of sub-Saharan Africa (sSA) where carbapenems are not available, may render ESBL-E infections untreatable. Gut mucosal colonisatio
Externí odkaz:
https://doaj.org/article/3774a76818714700a3a9edda4cea1aaa
Publikováno v:
Wellcome Open Research, Vol 4 (2019)
Background: Extended-spectrum beta-lactamase producing Enterobacteriaceae (ESBL-E) threaten human health; and, in areas of sub-Saharan Africa (sSA) where carbapenems are not available, may render ESBL-E infections untreatable. Gut mucosal colonisatio
Externí odkaz:
https://doaj.org/article/974574f43a034906a5b17a905605ce6a
Autor:
Derek Cocker, Kondwani Chidziwisano, Madalitso Mphasa, Taonga Mwapasa, Joseph M Lewis, Barry Rowlingson, Melodie Sammarro, Winnie Bakali, Chifundo Salifu, Allan Zuza, Mary Charles, Tamandani Mandula, Victor Maiden, Stevie Amos, Shevin T Jacob, Henry Kajumbula, Lawrence Mugisha, David Musoke, Rachel Byrne, Thomas Edwards, Rebecca Lester, Nicola Elviss, Adam P Roberts, Andrew C Singer, Christopher Jewell, Tracy Morse, Nicholas A Feasey
Publikováno v:
The Lancet Microbe.
Autor:
Vivien Price, Lucky Gift Ngwira, Joseph M. Lewis, Kate S. Baker, Sharon J. Peacock, Elita Jauneikaite, Nicholas Feasey
Funder: Rosetrees Trust
Whole-genome sequencing (WGS) has unparalleled ability to distinguish between bacteria, with many public health applications. The generation and analysis of WGS data require significant financial investment. We describe a
Whole-genome sequencing (WGS) has unparalleled ability to distinguish between bacteria, with many public health applications. The generation and analysis of WGS data require significant financial investment. We describe a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a27bbde2e7ef5862481d7cca287296dd
https://www.repository.cam.ac.uk/handle/1810/347709
https://www.repository.cam.ac.uk/handle/1810/347709