Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Joseph M Holden"'
Autor:
Joseph M Holden, Lauren K Wareham
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 6, Pp 1267-1268 (2023)
Externí odkaz:
https://doaj.org/article/e18afb1e60eb4c9488651bfd9d3c77bb
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Astrocytes are important regulators of blood flow and play a key role in the response to injury and disease in the central nervous system (CNS). Despite having an understanding that structural changes to these cells have consequences for local neurov
Externí odkaz:
https://doaj.org/article/23fcaeeaeea84c37ab2871b516840550
Autor:
Lauren K. Wareham, Joseph M. Holden, Olivia L. Bossardet, Robert O. Baratta, Brian J. Del Buono, Eric Schlumpf, David J. Calkins
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
The intraepithelial sub-basal nerve plexus of the cornea is characterized by a central swirl of nerve processes that terminate between the apical cells of the epithelium. This plexus is a critical component of maintaining homeostatic function of the
Externí odkaz:
https://doaj.org/article/9da9d9f7e3c24a5da3069e7c52b07094
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
IntroductionIdentification of early adaptive and maladaptive neuronal stress responses is an important step in developing targeted neuroprotective therapies for degenerative disease. In glaucoma, retinal ganglion cells (RGCs) and their axons undergo
Externí odkaz:
https://doaj.org/article/6b398316a73042a495ab710828d24ef4
Autor:
Alberto Esteban-Linares, Lauren K. Wareham, Thayer S. Walmsley, Joseph M. Holden, Matthew L. Fitzgerald, Zhiliang Pan, Ya-Qiong Xu, Deyu Li
Publikováno v:
Analytical chemistry. 94(36)
Dynamic observation of cell and tissue responses to elevated pressure could help our understanding of important physiological and pathological processes related to pressure-induced injury. Here, we report on a microfluidic platform capable of maintai
Autor:
Nolan R McGrady, Joseph M Holden, Marcio Ribeiro, Andrew M Boal, Michael L Risner, David J Calkins
Publikováno v:
Brain communications. 4(5)
Optic neuropathies are characterized by degeneration of retinal ganglion cell axonal projections to the brain, including acute conditions like optic nerve trauma and progressive conditions such as glaucoma. Despite different aetiologies, retinal gang
Autor:
Joseph M. Holden, Sara Al Hussein Al Awamlh, Louis-Philippe Croteau, Andrew M. Boal, Tonia S. Rex, Michael L. Risner, David J. Calkins, Lauren K. Wareham
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 6; Pages: 3066
The nitric oxide–guanylyl cyclase-1–cyclic guanylate monophosphate (NO–GC-1–cGMP) pathway is integral to the control of vascular tone and morphology. Mice lacking the alpha catalytic domain of guanylate cyclase (GC1−/−) develop retinal ga
Science and Faith Can—and Do—Support Each Other Science and Christianity are often presented as opposites, when in fact the order of the universe and the complexity of life powerfully testify to intelligent design. With this comprehensive resourc
Autor:
Steven Collins, Joseph M. Holden
“The scope of your learning...will be unlimited and enhanced by leaps and bounds as you use this wonderful tool.” from the Foreword by Walter C. Kaiser, Jr New discoveries are constantly being made as archaeologists work to uncover the ancient hi
Autor:
Ryan L. Earley, Justine E. Doherty, Patricia A. Wright, Perryn Kruth, Kelly D. Levesque, Andy J. Turko, Joseph M. Holden, Irene Yin-Liao
Publikováno v:
Journal of Experimental Biology.
Metabolic rate and life history traits vary widely both among and within species reflecting trade-offs in energy allocation, but the proximate and ultimate causes of variation are not well understood. We tested the hypothesis that these trade-offs ar