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of 8
pro vyhledávání: '"Joseph M Griffin"'
Publikováno v:
Journal of Physical Organic Chemistry. 29:768-772
Immobilised lipase B (Candida antarctica lipase B) is, perhaps unexpectedly, catalytically active in liquid ammonia and exhibits chain length selectivity in the ammonolysis of triglycerides. Using glycerol triacetate as the substrate, the ammonolysis
Publikováno v:
The Journal of Organic Chemistry. 80:7033-7039
Perfluorinated long chain alkyl amides aggregate in liquid ammonia with increasing concentration which reflects micelle-type formation based on changes in (19)F NMR chemical shifts. The critical micelle concentrations (cmc) decrease with increasing c
Publikováno v:
Journal of Physical Organic Chemistry. 26:1032-1037
The rates of ammonolysis of alkyl benzoate and phenylacetate esters in liquid ammonia increase with the acidity of the leaving group alcohol and show relatively large Bronsted βlg values of −1.18 and −1.34, respectively, when plotted against the
Publikováno v:
Toxicology Letters. 95:173-181
The environmental contaminant and occupational solvent trichloroethylene is metabolized to a reactive intermediate that covalently binds to specific hepatic proteins in exposed mice and rats. In order to compare covalent binding between humans and ro
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 57(2)
Exposure to relatively high levels of trichloroethylene has recently been shown to accelerate the development of an autoimmune response in the autoimmune prone MRL+/+ mice. The trichloroethylene-induced autoimmune response was associated with an incr
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 54(2)
Trichloroethylene is an organic solvent that is primarily used as a degreasing agent for metals. There is increasing evidence in both humans and animal models that trichloroethylene promotes the development of autoimmunity, but little is known about
Autor:
Kathleen M. Gilbert, Neil R. Pumford, Stephanie K. Jackson, Sarah J. Blossom, Joseph M. Griffin
Publikováno v:
Immunopharmacology. 46(2)
Trichloroethylene (1,1,2-trichloroethene) is a major environmental contaminant. There is increasing evidence relating exposure to trichloroethylene with autoimmunity. To investigate potential mechanisms, we treated the autoimmune-prone MRL +/+ mice w
Publikováno v:
Drug metabolism reviews. 31(4)
Trichloroethylene is an industrial solvent and has become a major environmental contaminant. Autoimmune-prone MRL +/+ mice were treated for up to 22 weeks with trichloroethylene in the drinking water (0, 2.5, and 5.0 mg/mL) in order to study the immu