Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Joseph M Catanzaro"'
Autor:
Joseph M Catanzaro, Jennifer L Guerriero, Jingxuan Liu, Erica Ullman, Namratha Sheshadri, John J Chen, Wei-Xing Zong
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19096 (2011)
Squamous cell carcinoma antigen (SCCA) belongs to the serine protease inhibitor (Serpin) family of proteins. Elevated expression of SCCA has been used as a biomarker for aggressive squamous cell carcinoma (SCC) in cancers of the cervix, lung, head an
Externí odkaz:
https://doaj.org/article/b7cc1539e2884f86907dc27773fcac51
Autor:
Wei-Xing Zong, Jianhua Zhang, Howard C. Crawford, Song Wu, Ji-An Pan, Emily I. Chen, Erica Ullman, Yu Sun, Alex J. Bott, Joseph M. Catanzaro, Namratha Sheshadri
Supplemental Materials and Methods, Figure Legend, Figures S1-6. Figure S1. SCCA1-expressing MCF10A cells become independent of the hormonal factors. Figure S2. Expression of SCCA1 leads to IL-6 production. Figure S3. The induction of UPR by SCCA1 is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4945a11a19c0d30e9e5867686ef8b982
https://doi.org/10.1158/0008-5472.22403801
https://doi.org/10.1158/0008-5472.22403801
Autor:
Ronen Marmorstein, Jiajun Zhu, Stephen A. Adam, Zhixun Dou, Terje Johansen, Adam M. Drake, Ji-An Pan, Andrejs Ivanov, Peter D. Adams, Joseph M. Catanzaro, Robert D. Goldman, Caiyue Xu, Brian C. Capell, Shelley L. Berger, M. Daniel Ricketts, Parisha P. Shah, Trond Lamark, Greg Donahue, Takeshi Shimi, Wei-Xing Zong
Publikováno v:
Nature
Macroautophagy (hereafter referred to as autophagy) is a catabolic membrane trafficking process that degrades a variety of cellular constituents, and is associated with human diseases1–3. While extensive studies have focused on autophagic turnover
Autor:
Wen-Xing Ding, Zhixun Dou, Ya Ping Jiang, Jorge Moscat, Nadia Jaber, Maria T. Diaz-Meco, Alex J. Bott, Joseph M. Catanzaro, Juei Suei Chen, Yu Sun, Chunying Du, Richard Z. Lin, Wei-Xing Zong, Bin Yang, Keiko Ozato, Ji-An Pan
Publikováno v:
Molecular Cell. 62:149-151
TRIM21 is a RING finger domain-containing ubiquitin E3 ligase whose expression is elevated in autoimmune disease. While TRIM21 plays an important role in immune activation during pathogen infection, little is known about its inherent cellular functio
Autor:
Yu Sun, Emily I. Chen, Joseph M. Catanzaro, Ji-An Pan, Howard C. Crawford, Alex J. Bott, Jianhua Zhang, Namratha Sheshadri, Erica Ullman, Song Wu, Wei-Xing Zong
Publikováno v:
Cancer Research. 74:6318-6329
The serine/cysteine protease inhibitor SCCA1 (SERPINB3) is upregulated in many advanced cancers with poor prognosis, but there is limited information about whether it makes functional contributions to malignancy. Here, we show that SCCA1 expression p
Publikováno v:
Behavioural Pharmacology. 25:582-598
Stress leads to neuroinflammatory and behavioral consequences through upregulation of inflammatory-related cytokines within the central nervous system such as interleukin-1β (IL-1β), which may be indicative of microglial priming/activation. Evidenc
Autor:
Jennifer L. Guerriero, Martha B. Furie, Richard R. Kew, Joseph M. Catanzaro, Wei-Xing Zong, Gregory J. Sabino, Howard C. Crawford, Dara Ditsworth
Publikováno v:
The Journal of Immunology. 186:3517-3526
Dysregulation of apoptosis is associated with the development of human cancer and resistance to anticancer therapy. We have previously shown in tumor xenografts that DNA alkylating agents induce sporadic cell necrosis and regression of apoptosis-defi
Autor:
Scott L. Friedman, Qing Jun Wang, M. Isabel Fiel, Jia-Hong Lu, Masatake Araki, Min Li, Zhenyu Yue, Joseph M. Catanzaro, Christian Behrends, Kimi Araki, Liqiang He, Wei-Xing Zong
Publikováno v:
Nature communications
Nature Communications
Nature Communications
The Beclin 1-Vps34 complex, the core component of the class III phosphatidylinositol-3 kinase (PI3K-III), binds Atg14L or UVRAG to control different steps of autophagy. However, the mechanism underlying the control of PI3K-III activity remains elusiv
Autor:
Chanjuan Shi, Yu Sun, Ji-An Pan, R. Scott Powers, Namratha Sheshadri, Wei-Xing Zong, Joseph M. Catanzaro, Jinyu Li, Howard C. Crawford
Publikováno v:
Nature communications
Mounting evidence indicates that oncogenic Ras can modulate cell autonomous inflammatory cytokine production, although the underlying mechanism remains unclear. Here we show that squamous cell carcinoma antigens 1 and 2 (SCCA1/2), members of the Serp
Autor:
Erica Ullman, John J. Chen, Namratha Sheshadri, Wei-Xing Zong, Jingxuan Liu, Jennifer L. Guerriero, Joseph M. Catanzaro
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19096 (2011)
Squamous cell carcinoma antigen (SCCA) belongs to the serine protease inhibitor (Serpin) family of proteins. Elevated expression of SCCA has been used as a biomarker for aggressive squamous cell carcinoma (SCC) in cancers of the cervix, lung, head an