Zobrazeno 1 - 10
of 172
pro vyhledávání: '"Joseph M, Miano"'
Autor:
Channabasavaiah B. Gurumurthy, Aidan R. O’Brien, Rolen M. Quadros, John Adams, Pilar Alcaide, Shinya Ayabe, Johnathan Ballard, Surinder K. Batra, Marie-Claude Beauchamp, Kathleen A. Becker, Guillaume Bernas, David Brough, Francisco Carrillo-Salinas, Wesley Chan, Hanying Chen, Ruby Dawson, Victoria DeMambro, Jinke D’Hont, Katharine Dibb, James D. Eudy, Lin Gan, Jing Gao, Amy Gonzales, Anyonya Guntur, Huiping Guo, Donald W. Harms, Anne Harrington, Kathryn E. Hentges, Neil Humphreys, Shiho Imai, Hideshi Ishii, Mizuho Iwama, Eric Jonasch, Michelle Karolak, Bernard Keavney, Nay-Chi Khin, Masamitsu Konno, Yuko Kotani, Yayoi Kunihiro, Imayavaramban Lakshmanan, Catherine Larochelle, Catherine B. Lawrence, Lin Li, Volkhard Lindner, Xian-De Liu, Gloria Lopez-Castejon, Andrew Loudon, Jenna Lowe, Loydie Jerome-Majeweska, Taiji Matsusaka, Hiromi Miura, Yoshiki Miyasaka, Benjamin Morpurgo, Katherine Motyl, Yo-ichi Nabeshima, Koji Nakade, Toshiaki Nakashiba, Kenichi Nakashima, Yuichi Obata, Sanae Ogiwara, Mariette Ouellet, Leif Oxburgh, Sandra Piltz, Ilka Pinz, Moorthy P. Ponnusamy, David Ray, Ronald J. Redder, Clifford J. Rosen, Nikki Ross, Mark T. Ruhe, Larisa Ryzhova, Ane M. Salvador, Sabrina Shameen Alam, Radislav Sedlacek, Karan Sharma, Chad Smith, Katrien Staes, Lora Starrs, Fumihiro Sugiyama, Satoru Takahashi, Tomohiro Tanaka, Andrew Trafford, Yoshihiro Uno, Leen Vanhoutte, Frederique Vanrockeghem, Brandon J. Willis, Christian S. Wright, Yuko Yamauchi, Xin Yi, Kazuto Yoshimi, Xuesong Zhang, Yu Zhang, Masato Ohtsuka, Satyabrata Das, Daniel J. Garry, Tino Hochepied, Paul Thomas, Jan Parker-Thornburg, Antony D. Adamson, Atsushi Yoshiki, Jean-Francois Schmouth, Andrei Golovko, William R. Thompson, K. C. Kent Lloyd, Joshua A. Wood, Mitra Cowan, Tomoji Mashimo, Seiya Mizuno, Hao Zhu, Petr Kasparek, Lucy Liaw, Joseph M. Miano, Gaetan Burgio
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-4 (2021)
Externí odkaz:
https://doaj.org/article/54d8d756b504456cad4fadda12ce0a6b
Autor:
Pan Gao, Qing Lyu, Amr R. Ghanam, Cicera R. Lazzarotto, Gregory A. Newby, Wei Zhang, Mihyun Choi, Orazio J. Slivano, Kevin Holden, John A. Walker, Anastasia P. Kadina, Rob J. Munroe, Christian M. Abratte, John C. Schimenti, David R. Liu, Shengdar Q. Tsai, Xiaochun Long, Joseph M. Miano
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-21 (2021)
Abstract Background Most single nucleotide variants (SNVs) occur in noncoding sequence where millions of transcription factor binding sites (TFBS) reside. Here, a comparative analysis of CRISPR-mediated homology-directed repair (HDR) versus the recen
Externí odkaz:
https://doaj.org/article/3ae7242cf5e844faa32def1a4de9bd76
Autor:
Ping Gao, Pan Gao, Jinjing Zhao, Shengshuai Shan, Wei Luo, Orazio J. Slivano, Wei Zhang, Akiko Tabuchi, Scott A. LeMaire, Lars Maegdefessel, Ying H. Shen, Joseph M. Miano, Harold A. Singer, Xiaochun Long
Publikováno v:
Redox Biology, Vol 41, Iss , Pp 101903- (2021)
Abdominal aortic aneurysm (AAA) is a catastrophic disease with little effective therapy. Myocardin related transcription factor A (MRTFA, MKL1) is a multifaceted transcription factor, regulating diverse biological processes. However, a detailed under
Externí odkaz:
https://doaj.org/article/d02a080db3b2478899c5ec252816e38c
Autor:
Channabasavaiah B. Gurumurthy, Aidan R. O’Brien, Rolen M. Quadros, John Adams, Pilar Alcaide, Shinya Ayabe, Johnathan Ballard, Surinder K. Batra, Marie-Claude Beauchamp, Kathleen A. Becker, Guillaume Bernas, David Brough, Francisco Carrillo-Salinas, Wesley Chan, Hanying Chen, Ruby Dawson, Victoria DeMambro, Jinke D’Hont, Katharine M. Dibb, James D. Eudy, Lin Gan, Jing Gao, Amy Gonzales, Anyonya R. Guntur, Huiping Guo, Donald W. Harms, Anne Harrington, Kathryn E. Hentges, Neil Humphreys, Shiho Imai, Hideshi Ishii, Mizuho Iwama, Eric Jonasch, Michelle Karolak, Bernard Keavney, Nay-Chi Khin, Masamitsu Konno, Yuko Kotani, Yayoi Kunihiro, Imayavaramban Lakshmanan, Catherine Larochelle, Catherine B. Lawrence, Lin Li, Volkhard Lindner, Xian-De Liu, Gloria Lopez-Castejon, Andrew Loudon, Jenna Lowe, Loydie A. Jerome-Majewska, Taiji Matsusaka, Hiromi Miura, Yoshiki Miyasaka, Benjamin Morpurgo, Katherine Motyl, Yo-ichi Nabeshima, Koji Nakade, Toshiaki Nakashiba, Kenichi Nakashima, Yuichi Obata, Sanae Ogiwara, Mariette Ouellet, Leif Oxburgh, Sandra Piltz, Ilka Pinz, Moorthy P. Ponnusamy, David Ray, Ronald J. Redder, Clifford J. Rosen, Nikki Ross, Mark T. Ruhe, Larisa Ryzhova, Ane M. Salvador, Sabrina Shameen Alam, Radislav Sedlacek, Karan Sharma, Chad Smith, Katrien Staes, Lora Starrs, Fumihiro Sugiyama, Satoru Takahashi, Tomohiro Tanaka, Andrew W. Trafford, Yoshihiro Uno, Leen Vanhoutte, Frederique Vanrockeghem, Brandon J. Willis, Christian S. Wright, Yuko Yamauchi, Xin Yi, Kazuto Yoshimi, Xuesong Zhang, Yu Zhang, Masato Ohtsuka, Satyabrata Das, Daniel J. Garry, Tino Hochepied, Paul Thomas, Jan Parker-Thornburg, Antony D. Adamson, Atsushi Yoshiki, Jean-Francois Schmouth, Andrei Golovko, William R. Thompson, K. C. Kent Lloyd, Joshua A. Wood, Mitra Cowan, Tomoji Mashimo, Seiya Mizuno, Hao Zhu, Petr Kasparek, Lucy Liaw, Joseph M. Miano, Gaetan Burgio
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-14 (2019)
Abstract Background CRISPR-Cas9 gene-editing technology has facilitated the generation of knockout mice, providing an alternative to cumbersome and time-consuming traditional embryonic stem cell-based methods. An earlier study reported up to 16% effi
Externí odkaz:
https://doaj.org/article/d080d0cd1924426bb1475dd31116c836
Autor:
Ganesh Warthi, Jessica L. Faulkner, Jaser Doja, Amr R. Ghanam, Pan Gao, Allison C. Yang, Orazio J. Slivano, Candee T. Barris, Taylor C. Kress, Scott D. Zawieja, Susan H. Griffin, Xiaoling Xie, Alan Ashworth, Christine K. Christie, William B. Bryant, Ajay Kumar, Michael J. Davis, Xiaochun Long, Lin Gan, Eric J. Belin de Chantemèle, Qing R. Lyu, Joseph M. Miano
Publikováno v:
Nature Cardiovascular Research. 1:1084-1100
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology.
Autor:
Ganesh, Warthi, Jessica L, Faulkner, Jaser, Doja, Amr R, Ghanam, Pan, Gao, Allison C, Yang, Orazio J, Slivano, Candee T, Barris, Taylor C, Kress, Scott D, Zawieja, Susan H, Griffin, Xiaoling, Xie, Alan, Ashworth, Christine K, Christie, William B, Bryant, Ajay, Kumar, Michael J, Davis, Xiaochun, Long, Lin, Gan, Eric J Belin, de Chantemèle, Qing, Lyu, Joseph M, Miano
Publikováno v:
Nat Cardiovasc Res
All current smooth muscle cell (SMC) Cre mice similarly recombine floxed alleles in vascular and visceral SMCs. Here, we present an Itga8-CreER(T2) knock-in mouse and compare its activity with a Myh11-CreER(T2) mouse. Both Cre drivers demonstrate equ
Autor:
W. Bart Bryant, Allison Yang, Susan H. Griffin, Wei Zhang, Ashiq M. Rafiq, Weiping Han, Ferenc Deak, Mary Katherine Mills, Xiaochun Long, Joseph M. Miano
Publikováno v:
CRISPR J
Microinjected transgenes, both large and small, are known to insert randomly into the mouse genome. Traditional methods of mapping a transgene are challenging, thus complicating breeding strategies and accurate interpretation of phenotypes, particula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2f88cdbe609ec95ccf52709b280fee6
https://europepmc.org/articles/PMC10123806/
https://europepmc.org/articles/PMC10123806/
Autor:
Wei Zhang, Jinjing Zhao, Lin Deng, Nestor Ishimwe, Jessica Pauli, Wen Wu, Shengshuai Shan, Wolfgang Kempf, Margaret D. Ballantyne, David Kim, Qing Lyu, Matthew Bennett, Julie Rodor, Adam W. Turner, Yao Wei Lu, Ping Gao, Mihyun Choi, Ganesh Warthi, Ha Won Kim, Margarida M. Barroso, William B. Bryant, Clint L. Miller, Neal L. Weintraub, Lars Maegdefessel, Joseph M. Miano, Andrew H Baker, Xiaochun Long
Publikováno v:
bioRxiv
Zhang, W, Zhao, J, Deng, L, Ishimwe, N, Pauli, J, Wu, W, Shan, S, Kempf, W, Ballantyne, M, Kim, D, Lyu, Q, Bennett, M, Rodor, J, Turner, A W, Lu, Y W, Gao, P, Choi, M, Warthi, G, Kim, H W, Barroso, M M, Bryant, W B, Miller, C L, Weintraub, N L, Maegdefessel, L, Miano, J M, Baker, A H & Long, X 2023, ' INKILN is a Novel Long Noncoding RNA Promoting Vascular Smooth Muscle Inflammation via Scaffolding MKL1 and USP10 ', Circulation . https://doi.org/10.1161/CIRCULATIONAHA.123.063760
Zhang, W, Zhao, J, Deng, L, Ishimwe, N, Pauli, J, Wu, W, Shan, S, Kempf, W, Ballantyne, M, Kim, D, Lyu, Q, Bennett, M, Rodor, J, Turner, A W, Lu, Y W, Gao, P, Choi, M, Warthi, G, Kim, H W, Barroso, M M, Bryant, W B, Miller, C L, Weintraub, N L, Maegdefessel, L, Miano, J M, Baker, A H & Long, X 2023, ' INKILN is a Novel Long Noncoding RNA Promoting Vascular Smooth Muscle Inflammation via Scaffolding MKL1 and USP10 ', Circulation . https://doi.org/10.1161/CIRCULATIONAHA.123.063760
BACKGROUND: Activation of vascular smooth muscle cell (VSMC) inflammation is vital to initiate vascular disease. The role of human-specific long noncoding RNAs in VSMC inflammation is poorly understood. METHODS: Bulk RNA sequencing in differentiated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07302f65d8a94a8cf420236d44dc5e52
https://doi.org/10.1101/2023.01.07.522948
https://doi.org/10.1101/2023.01.07.522948
Publikováno v:
Mammalian Genome
The number of human LncRNAs has now exceeded all known protein-coding genes. Most studies of human LncRNAs have been conducted in cell culture systems where various mechanisms of action have been worked out. On the other hand, efforts to elucidate th