Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Joseph M, Chalovich"'
Autor:
Joseph M. Chalovich
Publikováno v:
Frontiers in Physics, Vol 12 (2024)
At low free Ca2+, the actin binding proteins tropomyosin, troponin I, troponin T and troponin C inhibit contraction in striated muscles. Ca2+ activation alters the position of tropomyosin on actin to uncover binding sites for high affinity forms of m
Externí odkaz:
https://doaj.org/article/64eeda0fc1c645a69cae109aaedcf77f
Autor:
Lubomir T. Lubomirov, Mechthild M. Schroeter, Veronika Hasse, Marina Frohn, Doris Metzler, Maria Bust, Galyna Pryymachuk, Jürgen Hescheler, Olaf Grisk, Joseph M. Chalovich, Neil R. Smyth, Gabriele Pfitzer, Symeon Papadopoulos
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Stretch-induced vascular tone is an important element of autoregulatory adaptation of cerebral vasculature to maintain cerebral flow constant despite changes in perfusion pressure. Little is known as to the regulation of tone in senescent basilar art
Externí odkaz:
https://doaj.org/article/19a2ea5031624db0a6613a250fb065b3
Autor:
Alfredo Jesus López-Dávila, Joseph M. Chalovich, Stefan Zittrich, Birgit Piep, Faramarz Matinmehr, Andras Málnási-Csizmadia, Anna Á. Rauscher, Theresia Kraft, Bernhard Brenner, Robert Stehle
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
It has been shown that not only calcium but also strong binding myosin heads contribute to thin filament activation in isometrically contracting animal fast-twitch and cardiac muscle preparations. This behavior has not been studied in human muscle fi
Externí odkaz:
https://doaj.org/article/44a2581e2ee844f2b914999690386b9e
Publikováno v:
Biochemistry. 61:1103-1112
Publikováno v:
Biochemistry. 59:4189-4201
Calcium binding to troponin C (TnC) activates striated muscle contraction by removing TnI (troponin I) from its inhibitory site on actin. Troponin T (TnT) links TnI with tropomyosin, causing tropomyosin to move from an inhibitory position on actin to
Autor:
Jose R. Pinto, Li Zhu, Christopher Solís, John M. Robinson, Joseph M. Chalovich, Dylan Johnson, Maicon Landim-Vieira
Publikováno v:
Biochemistry
Calcium binding to troponin C (TnC) is insufficient for full activation of myosin ATPase activity by actin-tropomyosin-troponin. Previous attempts to investigate full activation utilized ATP-free myosin or chemically modified myosin to stabilize the
Publikováno v:
J Biol Chem
Striated muscle is activated by myosin- and actin-linked processes, with the latter being regulated through changes in the position of tropomyosin relative to the actin surface. The C-terminal region of cardiac troponin T (TnT), a tropomyosin-associa
Autor:
Peter J. Knight, David E. Casas-Mao, Glenn Carrington, Joseph M. Chalovich, Neil A. Ranson, Michelle Peckham, Charlotte A. Scarff
Publikováno v:
Nature
Myosin-2 is essential for processes as diverse as cell division and muscle contraction. Dephosphorylation of its regulatory light chain promotes an inactive, ‘shutdown’ state with the filament-forming tail folded onto the two heads1, which preven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f84b59919a3dfa843c2de0b23d56a345
https://eprints.whiterose.ac.uk/165604/1/Peckham_Main_final.pdf
https://eprints.whiterose.ac.uk/165604/1/Peckham_Main_final.pdf
Autor:
Li Zhu, Maicon Landim-Vieira, Michelle C. Rodriguez Garcia, J. Renato D. Pinto, Joseph M. Chalovich
Publikováno v:
Biophysical Journal. 121:254a
Autor:
Robert Stehle, Faramarz Matinmehr, Alfredo Jesus López-Dávila, András Málnási-Csizmadia, Bernhard Brenner, Stefan Zittrich, Joseph M. Chalovich, Theresia Kraft, Anna Á. Rauscher, Birgit Piep
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Frontiers in Physiology
Frontiers in Physiology
It has been shown that not only calcium but also strong binding myosin heads contribute to thin filament activation in isometrically contracting animal fast-twitch and cardiac muscle preparations. This behavior has not been studied in human muscle fi