Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Joseph L. Mann"'
Autor:
Santiago Correa, Emily L. Meany, Emily C. Gale, John H. Klich, Olivia M. Saouaf, Aaron T. Mayer, Zunyu Xiao, Celine S. Liong, Ryanne A. Brown, Caitlin L. Maikawa, Abigail K. Grosskopf, Joseph L. Mann, Juliana Idoyaga, Eric A. Appel
Publikováno v:
Advanced Science, Vol 9, Iss 28, Pp n/a-n/a (2022)
Abstract When properly deployed, the immune system can eliminate deadly pathogens, eradicate metastatic cancers, and provide long‐lasting protection from diverse diseases. Unfortunately, realizing these remarkable capabilities is inherently risky a
Externí odkaz:
https://doaj.org/article/532585a47bb445d384721979cafe579b
Autor:
Caitlin L. Maikawa, Peyton C. Chen, Eric T. Vuong, Leslee T. Nguyen, Joseph L. Mann, Andrea I. d'Aquino, Rayhan A. Lal, David M. Maahs, Bruce A. Buckingham, Eric A. Appel
Publikováno v:
Advanced Science, Vol 8, Iss 21, Pp n/a-n/a (2021)
Abstract Dual‐hormone replacement therapy with insulin and amylin in patients with type 1 diabetes has the potential to improve glucose management. Unfortunately, currently available formulations require burdensome separate injections at mealtimes
Externí odkaz:
https://doaj.org/article/d3a19ef54cb54dc096bc079b397dbf97
Autor:
Rayhan A. Lal, Caitlin L. Maikawa, Dana Lewis, Sam W. Baker, Anton A. A. Smith, Gillie A. Roth, Emily C. Gale, Lyndsay M. Stapleton, Joseph L. Mann, Anthony C. Yu, Santiago Correa, Abigail K. Grosskopf, Celine S. Liong, Catherine M. Meis, Doreen Chan, Joseph P. Garner, David M. Maahs, Bruce A. Buckingham, Eric A. Appel
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 4, Pp n/a-n/a (2021)
Abstract Understanding how automated insulin delivery (AID) algorithm features impact glucose control under full closed loop delivery represents a critical step toward reducing patient burden by eliminating the need for carbohydrate entries at mealti
Externí odkaz:
https://doaj.org/article/b08f806168ca4c878812280d3471a23a
Publikováno v:
Pharm Res
While excipients are often overlooked as the “inactive” ingredients in pharmaceutical formulations, they often play a critical role in protein stability and absorption kinetics. Recent work has identified an ultrafast absorbing insulin formulatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29226ce064830d08a2e77805d44575eb
https://doi.org/10.1007/s11095-022-03367-y
https://doi.org/10.1007/s11095-022-03367-y
Autor:
Matthew J. Webber, Peyton C. Chen, Bo Su, Joseph L. Mann, Eric A. Appel, Eric T. Vuong, Leslee T. Nguyen, Caitlin L. Maikawa, Andrea I. d’Aquino, Anton A. A. Autzen, Lei Zou
Publikováno v:
Biomacromolecules. 22:3565-3573
Proteins are an impactful class of therapeutics but can exhibit suboptimal therapeutic performance, arising from poor control over the timescale of clearance. Covalent PEGylation is one established strategy to extend circulation time but often at the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd21d63eeba8da52e104e7f6ba15745e
https://doi.org/10.1021/acs.biomac.1c00648
https://doi.org/10.1021/acs.biomac.1c00648
Autor:
Emily L. Meany, Santiago Correa, Abigail K. Grosskopf, Klich Jh, Emily C. Gale, Eric A. Appel, Olivia M. Saouaf, Juliana Idoyaga, Joseph L. Mann, Robert S. Brown, Caitlin L. Maikawa, Aaron T. Mayer, Xiao Z, Celine Liong
Publikováno v:
Advanced science (Weinheim, Baden-Wurttemberg, Germany). 9(28)
When properly deployed, the immune system can render deadly pathogens harmless, eradicate metastatic cancers, and provide long-lasting protection from diverse diseases. However, realizing these remarkable capabilities is inherently risky, as disrupti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1d9b8b487b28e28244a32e59e662336
https://pubmed.ncbi.nlm.nih.gov/35975424
https://pubmed.ncbi.nlm.nih.gov/35975424
Autor:
John H. Klich, Catherine M. Kasse, Joseph L. Mann, Yaoqi Huang, Andrea I. d’Aquino, Abigail K. Grosskopf, Julie Baillet, Gerald G. Fuller, Eric A. Appel
Publikováno v:
Adv Ther (Weinh)
Monoclonal antibodies are a staple in modern pharmacotherapy. Unfortunately, these biopharmaceuticals are limited by their tendency to aggregate in formulation, resulting in poor stability and often requiring low concentration drug formulations. More
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f1efed1a042adc94e530971307d1e5c
https://doi.org/10.1101/2022.05.25.493499
https://doi.org/10.1101/2022.05.25.493499
Autor:
Abigail K. Grosskopf, Joseph L. Mann, Julie Baillet, Hector Lopez Hernandez, Anton A. A. Autzen, Anthony C. Yu, Eric A. Appel
Designing yield stress fluids to exhibit desired functional properties is an integral challenge in many applications such as 3D printing, drilling, food formulation, fiber spinning, adhesives and injectable biomaterials. Extensibility in particular h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0a580e959a2519865e95850e811bf8a
https://doi.org/10.26434/chemrxiv-2022-t1q59
https://doi.org/10.26434/chemrxiv-2022-t1q59
Autor:
Doreen Chan, Jun-Chau Chien, Eneko Axpe, Louis Blankemeier, Samuel W. Baker, Sarath Swaminathan, Victoria A. Piunova, Dmitry Yu. Zubarev, Caitlin L. Maikawa, Abigail K. Grosskopf, Joseph L. Mann, H. Tom Soh, Eric A. Appel
Publikováno v:
Adv Mater
Biofouling on the surface of implanted medical devices severely hinders device functionality and drastically shortens device lifetime. Poly(ethylene glycol) and zwitterionic polymers are currently considered “gold standard” device coatings to red
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aced9f706771124c439be51758fb664a
https://pubmed.ncbi.nlm.nih.gov/35390209
https://pubmed.ncbi.nlm.nih.gov/35390209
Autor:
Joseph L. Mann, Catherine M. Meis, Abigail K. Grosskopf, Eric A. Appel, Erika E Salzman, Caitlin L. Maikawa, Anton A. A. Smith
Publikováno v:
ACS Biomaterials Science & Engineering
Biotherapeutics currently dominate the landscape of new drugs because of their exceptional potency and selectivity. Yet, the intricate molecular structures that give rise to these beneficial qualities also render them unstable in formulation. Hydroge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80ba6f51eb324ffa8ce857b5a5ab69f2
http://europepmc.org/articles/PMC8441967
http://europepmc.org/articles/PMC8441967