Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Joseph L. Hellerstein"'
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Computational models are increasingly used in high-impact decision making in science, engineering, and medicine. The National Aeronautics and Space Administration (NASA) uses computational models to perform complex experiments that are other
Externí odkaz:
https://doaj.org/article/4d392754300840158bb29212c1b6b3bc
Publikováno v:
F1000Research, Vol 8 (2019)
Biomedical simulations are widely used to understand disease, engineer cells, and model cellular processes. In this article, we explore how to improve the quality of biomedical simulations by developing simulation models using tools and practices emp
Externí odkaz:
https://doaj.org/article/d4d78f2237924702a4ce972cfc5b0931
Autor:
Woosub Shin, Joseph L. Hellerstein
Publikováno v:
Bioinformatics
Bioinformatics, 37(3), 388-395. Oxford University Press
Bioinformatics, 37(3), 388-395. Oxford University Press
Motivation The growing complexity of reaction-based models necessitates early detection and resolution of model errors. Considerable work has been done on the detection of mass balance errors, especially atomic mass analysis (AMA) (which compares the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9825be639a34185f23d7fbd7bff43ff3
http://europepmc.org/articles/PMC8058775
http://europepmc.org/articles/PMC8058775
Publikováno v:
Biosystems. 224:104836
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef1751e01e9394420f0c27f6db545d9e
https://doi.org/10.1016/j.biosystems.2023.104836
https://doi.org/10.1016/j.biosystems.2023.104836
Autor:
John H. Gennari, Woosub Shin, Maxwell Lewis Neal, Joseph L. Hellerstein, David P. Nickerson, Yuda Munarko, Anand Rampadarath, Herbert M. Sauro
The interests in repurposing and reusing systems biology models have been growing in recent years. Semantic annotations play an important role for this, as they provide crucial information on the meanings and functions of models. However, there are a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::856f0e75ee5c058a4543f2b7442d9f0a
https://doi.org/10.1101/2021.10.09.463757
https://doi.org/10.1101/2021.10.09.463757
Autor:
Woosub Shin, Joseph L. Hellerstein
MotivationThe growing complexity of reaction-based models necessitates early detection and resolution of model errors. This paper addresses mass balance errors, discrepancies between the mass of reactants and products in reaction specifications. One
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01e705c3f22c0931cfff5000b4e890d6
In this paper we examine the use of perturbation data to infer the underlying mechanistic dynamic model. The approach uses an evolutionary strategy to evolve networks based on a fitness criterion that measures the difference between the experimentall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1828567f07a9cac7bee6ad19883d9db8
Autor:
Kiri Choi, Stuart C. Sealfon, Stanley Gu, J. Kyle Medley, Lucian P. Smith, Herbert M. Sauro, Matthias König, Joseph L. Hellerstein
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 6, p e1006220 (2018)
PLoS Computational Biology
PLoS Computational Biology
The considerable difficulty encountered in reproducing the results of published dynamical models limits validation, exploration and reuse of this increasingly large biomedical research resource. To address this problem, we have developed Tellurium No
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6949453bb11bcc1a3df7d9aa12a5b097
https://doaj.org/article/154705802d6649ccbea844e4c4f26440
https://doaj.org/article/154705802d6649ccbea844e4c4f26440
Autor:
Stuart C. Sealfon, Joseph L. Hellerstein, Matthias König, Lucian P. Smith, Herbert M. Sauro, Kiri Choi, J. Kyle Medley, Stanley Gu
The considerable difficulty encountered in reproducing the results of published dynamical models limits validation, exploration and reuse of this increasingly large biomedical research resource. To address this problem, we have developed Tellurium No
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad464c9cb618954cb087cb28033f95ec
Autor:
Joseph L. Hellerstein, Alicia Clark
Publikováno v:
Proceedings of the 16th Python in Science Conference.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4da1c8e6c3430e3044901d300f61bcb1
https://doi.org/10.25080/shinma-7f4c6e7-007
https://doi.org/10.25080/shinma-7f4c6e7-007