Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Joseph L. Balwierczak"'
Publikováno v:
Biochemical Pharmacology. 49:291-296
The enzyme responsible for the conversion of exogenous big endothelindash1 to endothelindash1 by porcine coronary arterial smooth muscle has been shown to be a metalloprotease. The potencies of eight metalloprotease inhibitors for this endothelindash
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67907a12f553e98760be8e28d511e66d
https://doi.org/10.1016/0006-2952(94)00508-j
https://doi.org/10.1016/0006-2952(94)00508-j
Publikováno v:
European Journal of Pharmacology. 250:379-384
The conversion of exogenous big endothelin-1 to endothelin-1 by the smooth muscle of denuded porcine coronary arterial strips was measured by radioimmunoassay. Repeated incubations of a porcine coronary arterial strip with the same concentration of b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::679cc46846ba8c0333b7ea939b7d3956
https://doi.org/10.1016/0014-2999(93)90024-c
https://doi.org/10.1016/0014-2999(93)90024-c
Differential Cleavage of Urodilatin and Atrial Natriuretic Factor by Thrombin and Protease 3.4.24.11
Autor:
Radhika Ramannan, Yumi Sakane, R. D. Ghai, Carol Berry, Christine M. Krulan, Joseph L. Balwierczak
Publikováno v:
Journal of Enzyme Inhibition. 7:257-263
Human urodilatin (residues 95–126) and atrial natriuretic factor (residues 99–126, based on ANF prohor-mone sequence) were incubated separately with three proteases, thrombin, angiotensin converting enzyme (ACE), and neutral endopeptidase 3.4.24.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::666e999f81621ef77fcc913d89ddd42b
https://doi.org/10.3109/14756369309040768
https://doi.org/10.3109/14756369309040768
Autor:
Joseph L. Balwierczak
Publikováno v:
Journal of Cardiovascular Pharmacology. 22:S248-S251
The effects of endothelin-1 (ET-1) are mediated by two subclasses of the endothelin receptor, ETA and ETB. The Langendorff perfused rat heart was used to determine the endothelin receptor subtype mediating rat coronary vasoconstriction. ET-1 (EC50 =
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7baa5c44ed104aaf09107d77686a5d9
https://doi.org/10.1097/00005344-199322008-00066
https://doi.org/10.1097/00005344-199322008-00066
Publikováno v:
Cardiovascular Drug Reviews. 10:26-53
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65a76708974a6b21060a688e46978c00
https://doi.org/10.1111/j.1527-3466.1992.tb00235.x
https://doi.org/10.1111/j.1527-3466.1992.tb00235.x
Publikováno v:
Journal of Cardiovascular Pharmacology. 31:S71-S73
The purpose of this study was to identify endothelin-converting enzyme (ECE) inhibitors that also possess inhibitory activity for neutral endopeptidase 24.11 (NEP) and angiotensin-converting enzyme (ACE). The ortho-substituted benzofused macrocyclic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec236c7f2c7b251ea534f0e4d8f6b192
https://doi.org/10.1097/00005344-199800001-00023
https://doi.org/10.1097/00005344-199800001-00023
Autor:
Shiling Hu, Joseph L. Balwierczak, Dominick DelGrande, Helen S. Kim, Christine M. Krulan, George B. Weiss
Publikováno v:
Naunyn-Schmiedeberg's archives of pharmacology. 352(2)
The rank order of potency of a series of benzopyran and cyanoguanidine K+ channel openers (KCOs) for causing relaxation of the PGF2 alpha-precontracted porcine coronary artery was determined. Glyburide, an inhibitor of KATP channels, showed an appare
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78fef2bf1a0c36ae8fc70350cacbbb0c
https://pubmed.ncbi.nlm.nih.gov/7477446
https://pubmed.ncbi.nlm.nih.gov/7477446
Publikováno v:
Journal of biochemistry. 115(1)
A soluble protease which effectively inactivated endothelin-1 was purified 2,700-fold from rat kidney using DE52 anion exchange, concanavalin A-Sepharose, thiopropyl-Sepharose, and Mono P column chromatography. The overall recovery of enzyme activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a44f5f4b5e63958c749347426a6c2cd1
https://pubmed.ncbi.nlm.nih.gov/8188617
https://pubmed.ncbi.nlm.nih.gov/8188617
Autor:
Joseph L. Balwierczak
1. Changes in intracellular free Ca2+ concentration ([Ca2+]i) were measured simultaneously with changes in muscle tension by use of the fluorescent Ca2+ indicator, fura-2, in coronary arterial rings of the pig. 2. Changes in [Ca2+]i were measured by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3560bf488e7879c5252d9b4774442877
https://europepmc.org/articles/PMC1908573/
https://europepmc.org/articles/PMC1908573/
Autor:
Christine M. Krulan, Robin Sharif, F.Peter Field, George B. Weiss, Joseph L. Balwierczak, Mark J.S. Miller
Publikováno v:
European journal of pharmacology. 196(2)
CGS 21680 (2-[p-(2-carboxyethyl)phenylethylamino]-5'-N-ethyolcarboxamidoa denosine) is an adenosine agonist that has been reported recently to bind selectively to adenosine A2 receptors in rat brain. This adenosine agonist, and the parent compound NE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8c116bbd2539b123c8edc1dc8345305
https://pubmed.ncbi.nlm.nih.gov/1678715
https://pubmed.ncbi.nlm.nih.gov/1678715