Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Joseph Kushner"'
Autor:
Arnab, Mukherjee, Shinichi, Tsuchiwata, Cheng, Chang, Timothy, Nicholas, Chinyu, Su, Vu H, Le, Joseph, Kushner, Nicole, Kulisek
Publikováno v:
Clinical Pharmacology in Drug Development. 11:976-986
Tofacitinib is an oral, small molecule Janus kinase inhibitor for the treatment of ulcerative colitis (UC). We report a model-informed drug development approach for bridging efficacy from immediate-release (IR) to extended-release (XR) tofacitinib fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7fb92c77959ac3285bedc6b5183f801
https://doi.org/10.1002/cpdd.1106
https://doi.org/10.1002/cpdd.1106
Publikováno v:
State and Local Government Review. :0160323X2311739
In this paper, we examine whether a political budget cycle exists in municipal governments that fall under tight financial and institutional regulation by senior orders of government. For other levels of government, there is evidence that politicians
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::480320993fa267775637b68b5274abf9
https://doi.org/10.1177/0160323x231173920
https://doi.org/10.1177/0160323x231173920
Publikováno v:
AAPS PharmSciTech. 23(1)
The objective of this work is to develop a biorelevant dissolution method to support the clinical study for In Vitro In Vivo Correlation (IVIVC) of the first commercially approved single-layer extrudable core system (ECS) osmotic tablet - the 11 mg t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bbeb4c9790aac92777f8a7a0c37f85b
https://pubmed.ncbi.nlm.nih.gov/34850297
https://pubmed.ncbi.nlm.nih.gov/34850297
Autor:
John Kresevic, Daniel O. Blackwood, Matthew P. Mullarney, Jeffrey Moriarty, Joseph Kushner, William R. Ketterhagen
Publikováno v:
Drug Development and Industrial Pharmacy. 44:1350-1356
The purpose of this work was to develop a methodology that quantifies the extent of shear induced during an encapsulation process and show how formulation composition and manufacturing process designs can be changed to reduce the negative impact on d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d2581b63fe80a94788812f730d6d1b2
https://doi.org/10.1080/03639045.2018.1451877
https://doi.org/10.1080/03639045.2018.1451877
Autor:
Joseph Kushner
Publikováno v:
The Journal of Portfolio Management. 43:17-32
The author decomposes the returns of quantitative long–short factor portfolios to those attributable to “fundamental return”—the return due to underlying business operations—and those attributable to “multiple expansion”—the return du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::876b23647b5955883f961875e6ad7bd1
https://doi.org/10.3905/jpm.2017.43.4.017
https://doi.org/10.3905/jpm.2017.43.4.017
Autor:
Christine Alvey, Manisha Lamba, Thomas C. Stock, Mary Anne Nemeth, Andrew Blanchard, Joseph Kushner, Vincent DeMatteo, Ronnie Wang, Raymond Chen
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 147
Purpose To determine if a validated Level A in-vitro in-vivo correlation (IVIVC) could be achieved with the extrudable core system (ECS) osmotic tablet platform. Tofacitinib is an oral JAK inhibitor for the treatment of rheumatoid arthritis. Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4078ced05ba95790a18cae5032b9cc22
https://pubmed.ncbi.nlm.nih.gov/31863865
https://pubmed.ncbi.nlm.nih.gov/31863865
Publikováno v:
Journal of Clinical Pharmacology
Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis. An extended‐release (XR) formulation has been designed to provide a once‐daily (QD) dosing option to patients to achieve comparable pharmacokinetic (PK) para
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db19059fbd42a92b3e393f5f1a20673b
http://europepmc.org/articles/PMC5113768
http://europepmc.org/articles/PMC5113768
Autor:
Joseph Kushner, Tomson Ogwang
Publikováno v:
Canadian Public Policy. 40:283-291
In recent years Ontario's local electrical utilities, encouraged by the provincial government, have merged such that the number of utilities has been reduced from over 300 in the 1990s to 74 in 2011. This article examines the determinants of utility
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::297dc69365f921d6c15e154cc7852209
https://doi.org/10.3138/cpp.2013-016
https://doi.org/10.3138/cpp.2013-016
Publikováno v:
Journal of Wine Economics. 9:51-61
In this paper, we use three different goodness-of-fit tests for log-normality in conjunction with kernel nonparametric density estimation methods to examine both the size distribution of California North Coast wineries over time and by age. Our kerne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c806bf055a55ab60b1c5c256db9bd0f
https://doi.org/10.1017/jwe.2014.4
https://doi.org/10.1017/jwe.2014.4
Autor:
Joseph Kushner
Publikováno v:
International Journal of Pharmaceutics. 429:1-11
Turbula bottle blenders are often used in lab-scale experiments during early-stage pharmaceutical product development. Unfortunately, applying knowledge gained with these blenders to larger-sized diffusion mixers is limited by the lack of blending mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31acfd93d4d8cbd43ea9283dbf380950
https://doi.org/10.1016/j.ijpharm.2012.02.040
https://doi.org/10.1016/j.ijpharm.2012.02.040