Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Joseph K. Yu"'
Autor:
Joseph K. Yu, Padmini Sarathchandra, Adrian Chester, Magdi Yacoub, Thomas Brand, Jonathan T. Butcher
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Cardiac regeneration post-injury is a tantalizing feature of many lower vertebrates such as fishes and urodeles, but absent in adult humans. Restoration of pumping function is a key endpoint of cardiac regeneration, but very little is known
Externí odkaz:
https://doaj.org/article/887072574be04d6c86dd4928c7e5f23a
Autor:
David M, Shavelle, Thomas J, Heywood, Ajay V, Srivastava, Rahul, Agarwal, Julie B, Prillinger, Gregory J, Roberts, Joseph K, Yu, Matthew J, Price
Publikováno v:
The American Journal of Cardiology. 184:90-95
The objective of this study was to assess ambulatory hemodynamics after transcatheter edge-to-edge repair (TEER) of the mitral valve. Pulmonary artery pressure (PAP) measurements from implanted sensors were collected through a remote monitoring datab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eda949e344debb1ccee4281d5295223
https://doi.org/10.1016/j.amjcard.2022.08.036
https://doi.org/10.1016/j.amjcard.2022.08.036
Autor:
Thassio Mesquita, Rui Zhang, Jae Hyung Cho, Yen-Nien Lin, Lizbeth Sanchez, Joshua I. Goldhaber, Joseph K. Yu, Jialiu A. Liang, Weixin Liu, Natalia A. Trayanova, Eugenio Cingolani
Publikováno v:
Circulation, vol 145, iss 1
Circulation
Circulation
Background: The ability to increase heart rate during exercise and other stressors is a key homeostatic feature of the sinoatrial node (SAN). When the physiological heart rate response is blunted, chronotropic incompetence limits exercise capacity, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b79b6e4956c7859744ae150b210a69a3
https://doi.org/10.1161/circulationaha.121.054976
https://doi.org/10.1161/circulationaha.121.054976
Autor:
William H. Franceschi, Jialiu A Liang, Eric Sung, Farhad Pashakhanloo, Joseph K. Yu, Qinwen Huang, Natalia A. Trayanova, Patrick M. Boyle
Publikováno v:
Cardiovasc Res
Aims Direct remuscularization with pluripotent stem cell-derived cardiomyocytes (PSC-CMs) seeks to address the onset of heart failure post-myocardial infarction (MI) by treating the persistent muscle deficiency that underlies it. However, direct remu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8c2b224266df8f7693137f0d456ae94
https://doi.org/10.1093/cvr/cvab140
https://doi.org/10.1093/cvr/cvab140
Publikováno v:
J Mol Cell Cardiol
Acute engraftment arrhythmias (EAs) remain a serious complication of remuscularization therapy. Preliminary evidence suggests that a focal source underlies these EAs stemming from the automaticity of immature pluripotent stem cell-derived cardiomyocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61ea5fc8369343b8f27eb7039b51f2c5
https://europepmc.org/articles/PMC8766907/
https://europepmc.org/articles/PMC8766907/
Autor:
William H. Franceschi, Patrick M. Boyle, Farhad Pashakhanloo, Joseph K. Yu, Natalia A. Trayanova, Qinwen Huang
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)
Scientific Reports
Scientific Reports
Direct remuscularization approaches to cell-based heart repair seek to restore ventricular contractility following myocardial infarction (MI) by introducing new cardiomyocytes (CMs) to replace lost or injured ones. However, despite promising improvem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::587303bcf1e23a54c2b4cd488536b708
http://link.springer.com/article/10.1038/s41598-019-45684-0
http://link.springer.com/article/10.1038/s41598-019-45684-0
Autor:
Eugenio Cingolani, Natalia A. Trayanova, Thássio Ricardo Ribeiro Mesquita, Jialiu A Liang, Eduardo Marbán, Kevin Sompel, Joseph K. Yu
Publikováno v:
Circulation. 142
Introduction: While CI, or the inability of heart rate (HR) to adequately respond to exercise, is a strong indicator of mortality in HFpEF, treatment options remain limited as its mechanisms remain underexplored. Ionic remodeling of the SAN, both of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb87cab761c4fa11b932e46d3b05d16e
https://doi.org/10.1161/circ.142.suppl_3.17006
https://doi.org/10.1161/circ.142.suppl_3.17006
Autor:
Jonathan T. Butcher, Magdi H. Yacoub, Thomas Brand, Adrian H. Chester, Padmini Sarathchandra, Joseph K. Yu
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports
Scientific Reports
Cardiac regeneration post-injury is a tantalizing feature of many lower vertebrates such as fishes and urodeles, but absent in adult humans. Restoration of pumping function is a key endpoint of cardiac regeneration, but very little is known about the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f364096d4ef6a1ec4a6f6f48f069452f
https://doaj.org/article/887072574be04d6c86dd4928c7e5f23a
https://doaj.org/article/887072574be04d6c86dd4928c7e5f23a
Autor:
Thomas O'Hara, James R. Priest, Jason B. Harris, Marco V Perez, Luiz Belardinelli, Kristopher M. Kahlig, Thomas Quertermous, John A. West, Scott R. Ceresnak, Joseph K. Yu, Patrick M. Boyle, Daniela Macaya, Sean Michael Boyle, Euan A. Ashley, Megan E. Grove, Michael J. Clark, Charles Gawad, Sarah Garcia, Sridharan Rajamani, Stephen R. Quake, Natalia A. Trayanova, Katsuhide Maeda, Richard Chen, Lindsey Malloy-Walton, Christian Antolik, Kyla Dunn, Norma F. Neff, Anne M. Dubin, Frederick E. Dewey
Publikováno v:
Proceedings of the National Academy of Sciences. 113:11555-11560
Somatic mosaicism, the occurrence and propagation of genetic variation in cell lineages after fertilization, is increasingly recognized to play a causal role in a variety of human diseases. We investigated the case of life-threatening arrhythmia in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fac8c0bf23ed3c6bc4c65035aa2ab71
https://doi.org/10.1073/pnas.1607187113
https://doi.org/10.1073/pnas.1607187113
Publikováno v:
Biophysical Journal. 118:493a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46bfcb719a1981f6658de1c359badc91
https://doi.org/10.1016/j.bpj.2019.11.2728
https://doi.org/10.1016/j.bpj.2019.11.2728