Loss of skin elasticity is associated with pulmonary emphysema, biomarkers of inflammation, and matrix metalloproteinase activity in smokers

Autor: Michael E. O’Brien, Divay Chandra, Robert C. Wilson, Chad M. Karoleski, Carl R. Fuhrman, Joseph K. Leader, Jiantao Pu, Yingze Zhang, Alison Morris, Seyed Nouraie, Jessica Bon, Zsolt Urban, Frank C. Sciurba

Publikováno v: Respiratory Research, Vol 20, Iss 1, Pp 1-11 (2019)

Abstract Background Elastin breakdown and the resultant loss of lung elastic recoil is a hallmark of pulmonary emphysema in susceptible individuals as a consequence of tobacco smoke exposure. Systemic alterations to the synthesis and degradation of e

Externí odkaz: https://doaj.org/article/89107b51afc44518ab13e570f060b88e

Super U-Net: a modularized generalizable architecture

Autor: Cameron Beeche, Jatin P Singh, Joseph K Leader, Naciye S Gezer, Amechi P Oruwari, Kunal K Dansingani, Jay Chhablani, Jiantao Pu

Publikováno v: Pattern recognition. 128

To develop and validate a novel convolutional neural network (CNN) termed "Super U-Net" for medical image segmentation.Super U-Net integrates a dynamic receptive field module and a fusion upsampling module into the classical U-Net architecture. The m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::538d6bc9128f49ce7bad74eedb48767d
https://pubmed.ncbi.nlm.nih.gov/35528144

Predicting left/right lung volumes, thoracic cavity volume, and heart volume from subject demographics to improve lung transplant

Autor: Lucas Pu, Joseph K. Leader, Alaa Ali, Zihan Geng, David Wilson

Publikováno v: Medical Imaging 2023: Imaging Informatics for Healthcare, Research, and Applications.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a926613de447900d5ad56edc7999030f
https://doi.org/10.1117/12.2653616

The Association Between Lung Hyperinflation and Coronary Artery Disease in Smokers

Autor: Divay Chandra, Aman Gupta, Gregory L. Kinney, Carl R. Fuhrman, Joseph K. Leader, Alejandro A. Diaz, Jessica Bon, R. Graham Barr, George Washko, Matthew Budoff, John Hokanson, Frank C. Sciurba, James D. Crapo, Edwin K. Silverman, Barry J. Make, Elizabeth A. Regan, Terri Beaty, Ferdouse Begum, Adel R. Boueiz, Peter J. Castaldi, Michael Cho, Dawn L. DeMeo, Marilyn G. Foreman, Eitan Halper-Stromberg, Lystra P. Hayden, Craig P. Hersh, Jacqueline Hetmanski, Brian D. Hobbs, John E. Hokanson, Nan Laird, Christoph Lange, Sharon M. Lutz, Merry-Lynn McDonald, Margaret M. Parker, Dmitry Prokopenko, Dandi Qiao, Phuwanat Sakornsakolpat, Emily S. Wan, Sungho Won, Mustafa Al Qaisi, Harvey O. Coxson, Teresa Gray, MeiLan K. Han, Eric A. Hoffman, Stephen Humphries, Francine L. Jacobson, Philip F. Judy, Ella A. Kazerooni, Alex Kluiber, David A. Lynch, John D. Newell, James C. Ross, Raul San Jose Estepar, Joyce Schroeder, Jered Sieren, Douglas Stinson, Berend C. Stoel, Juerg Tschirren, Edwin Van Beek, Bram van Ginneken, Eva van Rikxoort, Carla G. Wilson, Robert Jensen, Jim Crooks, Douglas Everett, Camille Moore, null Strand, John Hughes, Gregory Kinney, Katherine Pratte, Kendra A. Young, Surya Bhatt, Carlos Martinez, Susan Murray, Xavier Soler, Farnoush Banaei-Kashani, Russell P. Bowler, Katerina Kechris, Jeffrey L. Curtis, Perry G. Pernicano, Nicola Hanania, Mustafa Atik, Aladin Boriek, Kalpatha Guntupalli, Elizabeth Guy, Amit Parulekar, Craig Hersh, John Austin, Belinda D’Souza, Byron Thomashow, Neil MacIntyre, H. Page McAdams, Lacey Washington, Charlene McEvoy, Joseph Tashjian, Robert Wise, Robert Brown, Nadia N. Hansel, Karen Horton, Allison Lambert, Nirupama Putcha, Richard Casaburi, Alessandra Adami, Hans Fischer, Janos Porszasz, Harry Rossiter, William Stringer, Michael E. DeBakey, Amir Sharafkhaneh, Charlie Lan, Christine Wendt, Brian Bell, Ken M. Kunisaki, Eugene Berkowitz, Gloria Westney, Russell Bowler, Richard Rosiello, David Pace, Gerard Criner, David Ciccolella, Francis Cordova, Chandra Dass, Gilbert D’Alonzo, Parag Desai, Michael Jacobs, Steven Kelsen, Victor Kim, A. James Mamary, Nathaniel Marchetti, Aditi Satti, Kartik Shenoy, Robert M. Steiner, Alex Swift, Irene Swift, Maria Elena Vega-Sanchez, Mark Dransfield, William Bailey, Surya P. Bhatt, Anand Iyer, Hrudaya Nath, J. Michael Wells, Joe Ramsdell, Paul Friedman, Andrew Yen, Alejandro P. Comellas, Karin F. Hoth, John Newell, Brad Thompson, Ella Kazerooni, Carlos H. Martinez, Joanne Billings, Abbie Begnaud, Tadashi Allen, Frank Sciurba, Carl Fuhrman, Joel Weissfeld, Antonio Anzueto, Sandra Adams, Diego Maselli-Caceres, Mario E. Ruiz

Publikováno v: Chest

BACKGROUND: Smokers manifest varied phenotypes of pulmonary impairment. RESEARCH QUESTION: Which pulmonary phenotypes are associated with coronary artery disease (CAD) in smokers? STUDY DESIGN AND METHODS: We analyzed data from the University of Pitt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1ace18852a510bd740a2be22038902b
https://doi.org/10.1016/j.chest.2021.04.066

Assessing retinal vein occlusion based on color fundus photographs using neural understanding network (NUN)

Autor: Cameron Beeche, Naciye S Gezer, Kartik Iyer, Omar Almetwali, Juezhao Yu, Yanchun Zhang, Rajeev Dhupar, Joseph K. Leader, Jiantao Pu

Objective To develop and validate a novel deep learning architecture to classify retinal vein occlusion (RVO) on color fundus photographs (CFPs) and reveal the image features contributing to the classification. Methods The neural understanding networ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa2f5d4e50eabac2f520c0ccdc6483c3
https://avesis.deu.edu.tr/publication/details/d8c613e7-f1ff-4afd-9349-e549e1371c91/oai