Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Joseph Jao-Yiu Sung"'
Autor:
Xiaoyu Liu, Man Liu, Haoran Wu, Wenshu Tang, Weiqin Yang, Thomas T.H. Chan, Lingyun Zhang, Shufen Chen, Zhewen Xiong, Jianxin Liang, Willis Wai-Yiu Si-Tou, Ting Shu, Jingqing Li, Jianquan Cao, Chengpeng Zhong, Hanyong Sun, Tsz Tung Kwong, Howard H.W. Leung, John Wong, Paul Bo-San Lai, Ka-Fai To, Tingxiu Xiang, Joseph Jao-Yiu Sung, Stephen Lam Chan, Jingying Zhou, Alfred Sze-Lok Cheng
Publikováno v:
JHEP Reports, Vol 6, Iss 7, Pp 101087- (2024)
Background & Aims: Recent studies demonstrated the importance of fibrosis in promoting an immunosuppressive liver microenvironment and thereby aggressive hepatocellular carcinoma (HCC) growth and resistance to immune checkpoint blockade (ICB), partic
Externí odkaz:
https://doaj.org/article/548a0fa4c9c849b8b8cb170ca38dbeaf
Autor:
Jingying Zhou, Huanyu Wang, Ting Shu, Jing Wang, Weiqin Yang, Jingqing Li, Lipeng Ding, Man Liu, Hanyong Sun, John Wong, Paul Bo-san Lai, Shun-Wa Tsang, Simon E. Ward, King-Lau Chow, Joseph Jao-yiu Sung, Alfred Sze-Lok Cheng
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107626- (2023)
Summary: Massive expansion of immature and suppressive myeloid cells is a common feature of malignant solid tumors. Over-expression of cyclin-dependent kinase 20, also known as cell cycle-related kinase (CCRK), in hepatocellular carcinoma (HCC) corre
Externí odkaz:
https://doaj.org/article/64467f2d4d01480781df060e9f589903
Publikováno v:
Gut Microbes, Vol 13, Iss 1 (2021)
The association of gut microbiota with gastrointestinal carcinogenesis has been heavily investigated since the recent advance in sequencing technology. Accumulating evidence has revealed the critical roles of commensal microbes in cancer progression.
Externí odkaz:
https://doaj.org/article/c147d7b8c93444c895eaf8fb05e0ed3b
Autor:
Vincent Wai-Sun Wong, Chi-Hang Tse, Tommy Tsan-Yuk Lam, Grace Lai-Hung Wong, Angel Mei-Ling Chim, Winnie Chiu-Wing Chu, David Ka-Wai Yeung, Patrick Tik-Wan Law, Hoi-Shan Kwan, Jun Yu, Joseph Jao-Yiu Sung, Henry Lik-Yuen Chan
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62885 (2013)
The human gut microbiota has profound influence on host metabolism and immunity. This study characterized the fecal microbiota in patients with nonalcoholic steatohepatitis (NASH). The relationship between microbiota changes and changes in hepatic st
Externí odkaz:
https://doaj.org/article/13328975a72b47a287651a1e7ca37c7e
Autor:
Man-Shan Li, Terrence Chi-Kong Lau, Sophie Ka-Ping Chan, Chi-Hang Wong, Patrick Kwok-Shing Ng, Joseph Jao-Yiu Sung, Henry Lik-Yuen Chan, Stephen Kwok-Wing Tsui
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21856 (2011)
Infection of hepatitis B virus (HBV) causes acute and chronic hepatitis and is closely associated with the development of cirrhosis and hepatocellular carcinoma (HCC). Previously, we demonstrated that the G1613A mutation in the HBV negative regulator
Externí odkaz:
https://doaj.org/article/206f8c3a1e6546508989f09fa081de17
Autor:
Wing-Kit Yip, Alfred Sze-Lok Cheng, Ranxu Zhu, Raymond Wai-Ming Lung, Daisy Pui-Fong Tsang, Suki Shuk-Kei Lau, Yangchao Chen, Jonathan Gabriel Sung, Paul Bo-San Lai, Enders Kai-On Ng, Jun Yu, Nathalie Wong, Ka-Fai To, Vincent Wai-Sun Wong, Joseph Jao-Yiu Sung, Henry Lik-Yuen Chan
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e22888 (2011)
BACKGROUND: The biological pathways and functional properties by which misexpressed microRNAs (miRNAs) contribute to liver carcinogenesis have been intensively investigated. However, little is known about the upstream mechanisms that deregulate miRNA
Externí odkaz:
https://doaj.org/article/9087198c9812485fa8a426d12db1ea4f
Autor:
Xiao-Xing Li, Grace Lai-Hung Wong, Ka-Fai To, Vincent Wai-Sun Wong, Larry Hin Lai, Dorothy Kai-Lai Chow, James Yun-Wong Lau, Joseph Jao-Yiu Sung, Chunming Ding
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7985 (2009)
Recent 16S ribosomal RNA gene (rRNA) molecular profiling of the stomach mucosa revealed a surprising complexity of microbiota. Helicobacter pylori infection and non-steroidal anti-inflammatory drug (NSAID) use are two main contributors to gastritis a
Externí odkaz:
https://doaj.org/article/33355a0476c5447eb927c77cae57d355
Highly Commended by the BMA Medical Book Awards for Internal Medicine!Written and edited by internationally renowned specialists, the third edition of Gastroenterological Endoscopy covers the entire spectrum of diagnostic and therapeutic procedures f
Autor:
Xiaoyu Liu, Jingying Zhou, Haoran Wu, Shufen Chen, Lingyun Zhang, Wenshu Tang, Liang Duan, Ying Wang, Eleanor McCabe, Mengying Hu, Zhuo Yu, Hanzhuang Liu, Chung Hang Jonathan Choi, Joseph Jao-yiu Sung, Leaf Huang, Rihe Liu, Alfred Sze-lok Cheng
Publikováno v:
Molecular Therapy. 31:119-133
The local microenvironment where tumors develop can shape cancer progression and therapeutic outcome. Emerging evidence demonstrate that the efficacy of immune-checkpoint blockade (ICB) is undermined by fibrotic tumor microenvironment (TME). The majo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6053fa210c7ac27584ac1c0a87e5dbc3
https://doi.org/10.1016/j.ymthe.2022.09.012
https://doi.org/10.1016/j.ymthe.2022.09.012
Autor:
Changan Liu, Siu-Kin Ng, Yanqiang Ding, Yufeng Lin, Weixin Liu, Sunny Hei Wong, Joseph Jao-Yiu Sung, Jun Yu
Publikováno v:
Oncogene. 41:3599-3610
The consistency of the associations between gastric mucosal microbiome and gastric cancer across studies remained unexamined. We aimed to identify universal microbial signatures in gastric carcinogenesis through a meta-analysis of gastric microbiome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::572abfb3dbbac6d523336b22a5c8368b
https://doi.org/10.1038/s41388-022-02377-9
https://doi.org/10.1038/s41388-022-02377-9