Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Joseph Jao Yiu Sung"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 4804-4815 (2023)
The human microbiome is an emerging research frontier due to its profound impacts on health. High-throughput microbiome sequencing enables studying microbial communities but suffers from analytical challenges. In particular, the lack of dedicated pre
Externí odkaz:
https://doaj.org/article/455954e4c90b418396db2c5ed9be092e
Autor:
Chaoran Liu, Wing‐Hoi Cheung, Jie Li, Simon Kwoon‐Ho Chow, Jun Yu, Sunny Hei Wong, Margaret Ip, Joseph Jao Yiu Sung, Ronald Man Yeung Wong
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 6, Pp 1393-1407 (2021)
Abstract Background Gut microbiota dysbiosis and sarcopenia commonly occur in the elderly. Although the concept of the gut–muscle axis has been raised, the casual relationship is still unclear. This systematic review analyses the current evidence o
Externí odkaz:
https://doaj.org/article/4fd8af8b49a04f409c80f5b07d4a55b2
Autor:
Jie Li, Wing Tung Percy Ho, Chaoran Liu, Simon Kwoon-Ho Chow, Margaret Ip, Jun Yu, Hei Sunny Wong, Wing-Hoi Cheung, Joseph Jao Yiu Sung, Ronald Man Yeung Wong
Publikováno v:
Bone & Joint Research, Vol 10, Iss 1, Pp 51-59 (2021)
Aims: The effect of the gut microbiota (GM) and its metabolite on bone health is termed the gut-bone axis. Multiple studies have elucidated the mechanisms but findings vary greatly. A systematic review was performed to analyze current animal models a
Externí odkaz:
https://doaj.org/article/8b1e16cb08a24d71860c287b514e1a8d
Autor:
Xiaoxuan Xia, William Ka Kei Wu, Sunny Hei Wong, Dabin Liu, Thomas Ngai Yeung Kwong, Geicho Nakatsu, Pearlly S. Yan, Yu-Ming Chuang, Michael Wing-Yan Chan, Olabisi Oluwabukola Coker, Zigui Chen, Yun Kit Yeoh, Liuyang Zhao, Xiansong Wang, Wing Yin Cheng, Matthew Tak Vai Chan, Paul Kay Sheung Chan, Joseph Jao Yiu Sung, Maggie Haitian Wang, Jun Yu
Publikováno v:
Microbiome, Vol 8, Iss 1, Pp 1-13 (2020)
Abstract Background Altered microbiome composition and aberrant promoter hypermethylation of tumor suppressor genes (TSGs) are two important hallmarks of colorectal cancer (CRC). Here we performed concurrent 16S rRNA gene sequencing and methyl-CpG bi
Externí odkaz:
https://doaj.org/article/48ee2fc5625d4486a4c1566784db8387
Autor:
Tsz Tung Kwong, Chi Hang Wong, Jing Ying Zhou, Alfred Sze Lok Cheng, Joseph Jao Yiu Sung, Anthony Wing Hung Chan, Stephen Lam Chan
Publikováno v:
JHEP Reports, Vol 3, Iss 2, Pp 100224- (2021)
Background & aims: Immune checkpoint blockade (ICB) has been approved for treatment of hepatocellular carcinoma (HCC). However, many patients with advanced HCC are non-responders to ICB monotherapy. Cytotoxic chemotherapy has been proposed to modulat
Externí odkaz:
https://doaj.org/article/a6f98b12474d47d587e8081f2e31470b
Autor:
Xiaoyu Liu, Man Liu, Haoran Wu, Wenshu Tang, Weiqin Yang, Thomas T.H. Chan, Lingyun Zhang, Shufen Chen, Zhewen Xiong, Jianxin Liang, Willis Wai-Yiu Si-Tou, Ting Shu, Jingqing Li, Jianquan Cao, Chengpeng Zhong, Hanyong Sun, Tsz Tung Kwong, Howard H.W. Leung, John Wong, Paul Bo-San Lai, Ka-Fai To, Tingxiu Xiang, Joseph Jao-Yiu Sung, Stephen Lam Chan, Jingying Zhou, Alfred Sze-Lok Cheng
Publikováno v:
JHEP Reports, Vol 6, Iss 7, Pp 101087- (2024)
Background & Aims: Recent studies demonstrated the importance of fibrosis in promoting an immunosuppressive liver microenvironment and thereby aggressive hepatocellular carcinoma (HCC) growth and resistance to immune checkpoint blockade (ICB), partic
Externí odkaz:
https://doaj.org/article/548a0fa4c9c849b8b8cb170ca38dbeaf
Highly Commended by the BMA Medical Book Awards for Internal Medicine!Written and edited by internationally renowned specialists, the third edition of Gastroenterological Endoscopy covers the entire spectrum of diagnostic and therapeutic procedures f
Autor:
Xiaoyu Liu, Jingying Zhou, Haoran Wu, Shufen Chen, Lingyun Zhang, Wenshu Tang, Liang Duan, Ying Wang, Eleanor McCabe, Mengying Hu, Zhuo Yu, Hanzhuang Liu, Chung Hang Jonathan Choi, Joseph Jao-yiu Sung, Leaf Huang, Rihe Liu, Alfred Sze-lok Cheng
Publikováno v:
Molecular Therapy. 31:119-133
The local microenvironment where tumors develop can shape cancer progression and therapeutic outcome. Emerging evidence demonstrate that the efficacy of immune-checkpoint blockade (ICB) is undermined by fibrotic tumor microenvironment (TME). The majo
Autor:
Changan Liu, Siu-Kin Ng, Yanqiang Ding, Yufeng Lin, Weixin Liu, Sunny Hei Wong, Joseph Jao-Yiu Sung, Jun Yu
Publikováno v:
Oncogene. 41:3599-3610
The consistency of the associations between gastric mucosal microbiome and gastric cancer across studies remained unexamined. We aimed to identify universal microbial signatures in gastric carcinogenesis through a meta-analysis of gastric microbiome
Autor:
Jianning Zhai, Huarong Chen, Chi Chun Wong, Yao Peng, Hongyan Gou, Jingwan Zhang, Yasi Pan, Danyu Chen, Yufeng Lin, Shiyan Wang, Wei Kang, Ka Fai To, Zhiwei Chen, Yuqiang Nie, Housheng Hansen He, Joseph Jao-Yiu Sung, Jun Yu
Publikováno v:
Gastroenterology.