Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Joseph J. Topczewski"'
Autor:
Matthew R. Porter, Haiyan Xiao, Sanjay Maity, Nora Vail, Sylvia B. Smith, Joseph J. Topczewski
Publikováno v:
ACS Omega, Vol 5, Iss 50, Pp 32724-32737 (2020)
Externí odkaz:
https://doaj.org/article/620419c85bbe407281a4084f471c859d
Autor:
Amy A. Ott, Joseph J. Topczewski
Publikováno v:
ARKIVOC, Vol 2019, Iss 1, Pp 1-17 (2019)
Externí odkaz:
https://doaj.org/article/9c647980a500440c9b85c38b79572c0e
Publikováno v:
The Journal of Organic Chemistry. 86:11419-11433
Reported herein is a mechanistic investigation into the palladium-catalyzed decarboxylative cross-coupling of sodium benzoates and chloroarenes. The reaction was found to be first-order in Pd. A minimal substituent effect was observed with respect to
Publikováno v:
ACS Catalysis. 11:9578-9587
Publikováno v:
Org Lett
The Banert cascade of propargylic azides can be promoted by simple silver salts, and the triazafulvene intermediate can be intercepted by carbon nucleophiles. Various indoles (>25 examples, up to 92% yield) and electron-rich heterocycles were effecti
Autor:
Haiyan Xiao, Joseph J. Topczewski, Sylvia B. Smith, Sanjay Maity, Nora R. Vail, Matthew R. Porter
Publikováno v:
ACS Omega
ACS Omega, Vol 5, Iss 50, Pp 32724-32737 (2020)
ACS Omega, Vol 5, Iss 50, Pp 32724-32737 (2020)
The σ1 receptor is implicated in regulating a diverse range of physiology and is a target for developing therapies for cancer, pain management, neural degradation, and COVID-19. This report describes 36 phenethylamine-containing 3-amino-chromane lig
Publikováno v:
Journal of the American Chemical Society. 142:13210-13218
This report details a decarboxylative cross-coupling of (hetero)aryl carboxylates with iodoarenes in the presence of a gold catalyst (>25 examples, up to 96% yield). This reaction is site specific, which overcomes prior limitations associated with go
Autor:
En Chih Liu, Joseph J. Topczewski
Publikováno v:
The Journal of Organic Chemistry. 85:4560-4564
The molecule 2,5-difluoro-7,7,8,8-tetracyanoquinodimethane (F2-TCNQ) is an organic semiconductor with many promising properties, including high charge mobility (μ). However, an efficient gram-scale synthesis of F2-TCNQ has not been fully documented.
Autor:
Mary H. Packard, Joseph J. Topczewski, Juliana R. Alexander, Alanna M. Hildebrandt, Amy A. Ott
Publikováno v:
J Org Chem
Triazoles are privileged heterocycles for a variety of applications. The synthesis of 1H-triazoles can be accomplished by the Banert cascade from propargylic azides. Depending on the substrate and conditions, the Banert cascade can proceed by either
Autor:
Ian A. Tonks, Jason D. Goodpaster, Evan P. Beaumier, Amy A. Ott, Zachary W. Davis-Gilbert, Xuelan Wen, T. Alexander Wheeler, Joseph J. Topczewski
Publikováno v:
Chemical Science
The ring-opening oxidative amination of methylenecyclopropanes (MCPs) with diazenes catalyzed by py3TiCl2(NR) complexes is reported. This reaction selectively generates branched α-methylene imines as opposed to linear α,β-unsaturated imines, which