Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Joseph J. Meissler"'
Autor:
Kolter B. Grigsby, Regina A. Mangieri, Amanda J. Roberts, Marcelo F. Lopez, Evan J. Firsick, Kayla G. Townsley, Alan Beneze, Jessica Bess, Toby K. Eisenstein, Joseph J. Meissler, John M. Light, Jenny Miller, Susan Quello, Farhad Shadan, Michael Skinner, Heather C. Aziz, Pamela Metten, Richard A. Morrisett, John C. Crabbe, Marisa Roberto, Howard C. Becker, Barbara J. Mason, Angela R. Ozburn
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 6 (2023)
Treatment options for alcohol use disorders (AUDs) have minimally advanced since 2004, while the annual deaths and economic toll have increased alarmingly. Phosphodiesterase type 4 (PDE4) is associated with alcohol and nicotine dependence. PDE4 inhib
Externí odkaz:
https://doaj.org/article/53c157cfc03541cb8b6a5df7afdc653b
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Previous work from our laboratory showed that a CB2 selective agonist, O-1966, blocked the proliferative response of C57BL/6 mouse spleen cells exposed to spleen cells of C3HeB/FeJ mice in vitro in the mixed lymphocyte reaction (MLR). The MLR is wide
Externí odkaz:
https://doaj.org/article/ea44f8c02cfd4d0b9892db7071acca4a
Autor:
Ray R. Denny, Krista L. Connelly, Marco G. Ghilotti, Joseph J. Meissler, Daohai Yu, Toby K. Eisenstein, Ellen M. Unterwald
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Post-traumatic stress disorder (PTSD) is initiated by traumatic-stress exposure and manifests into a collection of symptoms including increased anxiety, sleep disturbances, enhanced response to triggers, and increased sympathetic nervous system arous
Externí odkaz:
https://doaj.org/article/6c13f88a27694befaac5e2a0e2285ccf
Autor:
Marita Chakhtoura, Robert W. Chain, Priscila Y. Sato, Connie C. Qiu, Michael H. Lee, Joseph J. Meissler, Toby K. Eisenstein, Walter J. Koch, Roberto Caricchio, Stefania Gallucci
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Attenuating the innate immunity activation could ameliorate inflammation and disease in settings such as transplant rejection or autoimmunity. Recently, a pivotal role for metabolic re-programming in TLR-induced dendritic cell (DC) activation has eme
Externí odkaz:
https://doaj.org/article/1b1c991004284f68a051fbce56f145af
Autor:
Saadet Inan, Joseph J Meissler, Aryan Shekarabi, Jeffrey Foss, Sonita Wiah, Toby K Eisenstein, Scott M. Rawls
Psychostimulant exposure and withdrawal cause neuroimmune dysregulation and anxiety that contributes to dependence and relapse. Here, we tested the hypothesis that abstinence from the synthetic cathinone MDPV (methylenedioxypyrovalerone) produces anx
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c640f533e91b4c83499bbf3e6a8a34a0
https://doi.org/10.21203/rs.3.rs-2326678/v1
https://doi.org/10.21203/rs.3.rs-2326678/v1
Autor:
Saadet Inan, Joseph J Meissler, Aryan Shekarabi, Jeffrey Foss, Sonita Wiah, Toby K Eisenstein, Scott M. Rawls
Publikováno v:
Brain Research. 1806:148310
Autor:
Raghava Potula, Taylor A. Gentile, Joseph J. Meissler, Aryan Shekarabi, Sonita Wiah, Daniel J. Farkas, Saadet Inan, Toby K. Eisenstein, Scott M. Rawls
Publikováno v:
Brain, behavior, and immunity. 107
P2X7 receptors are dysregulated during psychostimulant exposure. Furthermore, P2X7 receptors enhance endogenous systems (e.g., cytokines, dopamine, and glutamate) that facilitate psychostimulant addiction. Therefore, using mouse locomotor, conditione
Autor:
Michael R, Ruff, Saadet, Inan, Xiang Qun, Shi, Joseph J, Meissler, Martin W, Adler, Toby K, Eisenstein, Ji, Zhang
Publikováno v:
Life Sci
AIMS: We determined the ability of the multi-chemokine receptor (CCR2/CCR5/CCR8) antagonist RAP-103 to modulate pain behaviors in an acute model of surgical pain, with and without an added opioid (morphine), and by itself in a chronic model of Strept
Autor:
Ellen B. Geller, Martin W. Adler, Christopher S. Tallarida, Saadet Inan, Scott M. Rawls, Alan Cowan, Xiaohong Chen, Toby K. Eisenstein, Joseph J. Meissler
Publikováno v:
Mil Med
Introduction Although opioids are widely prescribed for pain, in many circumstances, they have only modest efficacy. Preclinical studies have shown that chemokines, immune mediators released during tissue injury and inflammation, can desensitize opio
Autor:
Christopher S. Tallarida, Alan Cowan, Xiaohong Chen, Eric M. Eisenstein, Joseph J. Meissler, James E. Barrett, Mia N. Watson, Menahem Doura, Ellen B. Geller, Martin W. Adler, Scott M. Rawls, Saadet Inan, Toby K. Eisenstein
Publikováno v:
Life Sciences. 285:120014
Aims We have shown that chemokines injected into the periaqueductal gray region of the brain blocks opioid-induced analgesia in the rat cold-water tail flick test (CWTF). The present experiments tested whether chemokine receptor antagonists (CRAs), i