Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Joseph J. Gillespie"'
Autor:
Stephanie S. Lehman, Victoria I. Verhoeve, Timothy P. Driscoll, John F. Beckmann, Joseph J. Gillespie
Publikováno v:
mBio, Vol 15, Iss 5 (2024)
ABSTRACTRecent metagenome-assembled genome (MAG) analyses have profoundly impacted Rickettsiology systematics. The discovery of basal lineages (novel families Mitibacteraceae and Athabascaceae) with predicted extracellular lifestyles exposed an evolu
Externí odkaz:
https://doaj.org/article/65f65e5bebd64fb38fdd61e4a0a03ed8
Autor:
Spiridon E. Sevdalis, Kristen M. Varney, Mary E. Cook, Joseph J. Gillespie, Edwin Pozharski, David J. Weber
Publikováno v:
Toxins, Vol 16, Iss 8, p 330 (2024)
Pathogenic Bacillus and clostridial (i.e., Clostridium and Clostridioides) bacteria express a diverse repertoire of effector proteins to promote disease. This includes production of binary toxins, which enter host epithelial cells and seriously damag
Externí odkaz:
https://doaj.org/article/fb6b87923caf4170ab7aade83123e249
Autor:
Hyojik Yang, Victoria I. Verhoeve, Courtney E. Chandler, Shreeram Nallar, Greg A. Snyder, Robert K. Ernst, Joseph J. Gillespie
Publikováno v:
mSphere, Vol 9, Iss 2 (2024)
ABSTRACT Rickettsiae are Gram-negative obligate intracellular parasites of numerous eukaryotes. Human pathogens of the transitional group (TRG), typhus group (TG), and spotted fever group (SFG) rickettsiae infect blood-feeding arthropods, have dissim
Externí odkaz:
https://doaj.org/article/3211a0956409418ebdd41ac52a168d26
Autor:
Casey E. Hofstaedter, Courtney E. Chandler, Charles M. Met, Joseph J. Gillespie, Janette M. Harro, David R. Goodlett, David A. Rasko, Robert K. Ernst
Publikováno v:
mBio, Vol 15, Iss 2 (2024)
ABSTRACT Pseudomonas aeruginosa can survive in a myriad of environments, partially due to modifications of its lipid A, the membrane anchor of lipopolysaccharide. We previously demonstrated that divergent late acyltransferase paralogs, HtrB1 and HtrB
Externí odkaz:
https://doaj.org/article/ea0cd43ff14a45149c62cd93f51dc5bd
Autor:
Suparat Giengkam, Chitrasak Kullapanich, Jantana Wongsantichon, Haley E. Adcox, Joseph J. Gillespie, Jeanne Salje
Publikováno v:
mSphere, Vol 8, Iss 6 (2023)
ABSTRACTThe rickettsial human pathogen Orientia tsutsugamushi (Ot) is an obligate intracellular Gram-negative bacterium with one of the most highly fragmented and repetitive genomes of any organism. Around 50% of its ~2.3-Mb genome is composed of rep
Externí odkaz:
https://doaj.org/article/46c1e32cfeba4478afaa781a70b40077
Autor:
Victoria I. Verhoeve, Tyesha D. Fauntleroy, Riley G. Risteen, Timothy P. Driscoll, Joseph J. Gillespie
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
BackgroundThe genus Rickettsia (Alphaproteobacteria: Rickettsiales) encompasses numerous obligate intracellular species with predominantly ciliate and arthropod hosts. Notable species are pathogens transmitted to mammals by blood-feeding arthropods.
Externí odkaz:
https://doaj.org/article/25f44db9a2364b5f98ee5d3573edc243
Autor:
Timothy P. Driscoll, Victoria I. Verhoeve, Joseph J. Gillespie, J. Spencer Johnston, Mark L. Guillotte, Kristen E. Rennoll-Bankert, M. Sayeedur Rahman, Darren Hagen, Christine G. Elsik, Kevin R. Macaluso, Abdu F. Azad
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-19 (2020)
Abstract Background Fleas (Insecta: Siphonaptera) are small flightless parasites of birds and mammals; their blood-feeding can transmit many serious pathogens (i.e., the etiological agents of bubonic plague, endemic and murine typhus). The lack of fl
Externí odkaz:
https://doaj.org/article/65f7da03c7cb4e78addaea291ae4f199
Autor:
Sharanjeet Atwal, Suthida Chuenklin, Edward M. Bonder, Juan Flores, Joseph J. Gillespie, Timothy P. Driscoll, Jeanne Salje
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
ABSTRACT Peptidoglycan (PG) is a highly cross-linked peptide-glycan mesh that confers structural rigidity and shape to most bacterial cells. Polymerization of new PG is usually achieved by the concerted activity of two membrane-bound machineries, cla
Externí odkaz:
https://doaj.org/article/e3c8a708b4ba43578dbed7bc6369677f
Autor:
Mark L. Guillotte, Courtney E. Chandler, Victoria I. Verhoeve, Joseph J. Gillespie, Timothy P. Driscoll, M. Sayeedur Rahman, Robert K. Ernst, Abdu F. Azad
Publikováno v:
mSphere, Vol 6, Iss 3 (2021)
Spikes in rickettsioses occur as deforestation, urbanization, and homelessness increase human exposure to blood-feeding arthropods. Still, effective Rickettsia
Externí odkaz:
https://doaj.org/article/bb762e802c344f9f861e67e13a56a538
Autor:
Victoria I. Verhoeve, Mariah L Plumer, Timothy P. Driscoll, Kevin R. Macaluso, Abdu F. Azad, Joseph J. Gillespie
Publikováno v:
Mitochondrial DNA. Part B. Resources, Vol 5, Iss 3, Pp 3422-3424 (2020)
The cat flea, Ctenocephalides fells, is widely recognized as a global veterinary pest and a vector of pathogenic bacteria. We recently reported on the C. felis nuclear genome, which is characterized by over 38% protein coding gene duplication, extens
Externí odkaz:
https://doaj.org/article/ecc0f888213d481db5840993bf4579ae