Zobrazeno 1 - 10
of 691
pro vyhledávání: '"Joseph J Eron"'
Autor:
Tin Phan, Carolin Zitzmann, Kara W Chew, Davey M Smith, Eric S Daar, David A Wohl, Joseph J Eron, Judith S Currier, Michael D Hughes, Manish C Choudhary, Rinki Deo, Jonathan Z Li, Ruy M Ribeiro, Ruian Ke, Alan S Perelson, ACTIV-2/A5401 Study Team
Publikováno v:
PLoS Pathogens, Vol 20, Iss 4, p e1011680 (2024)
To mitigate the loss of lives during the COVID-19 pandemic, emergency use authorization was given to several anti-SARS-CoV-2 monoclonal antibody (mAb) therapies for the treatment of mild-to-moderate COVID-19 in patients with a high risk of progressin
Externí odkaz:
https://doaj.org/article/78108cfe10f347ff8cf97ead03163c63
Autor:
Greer Burkholder, Susan R Heckbert, Barbara N Harding, Bridget M Whitney, Robin M Nance, Heidi M Crane, W Christopher Mathews, Joseph J Eron, Peter W Hunt, Paul Volberding, Benigno Rodriguez, Michael S Saag, Mari M Kitahata, Joseph A C Delaney
Publikováno v:
BMJ Open, Vol 10, Iss 3 (2020)
Externí odkaz:
https://doaj.org/article/28b59c9b068d4cb99df435f2a86b8ae0
Autor:
Sonia Vibhakar Patel, Dushyantha T Jayaweera, Keri N Althoff, Joseph J Eron, Janna Radtchenko, Anthony Mills, Graeme Moyle, Steven Santiago, Paul E Sax, Jason Gillman, Karam Mounzer, Richard A Elion, Gregory D Huhn
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0228847 (2020)
The advent of direct-acting antiviral (DAA) therapies has dramatically transformed HCV treatment, with most recent trials demonstrating high efficacy rates (>90%) across all genotypes and special populations, including patients with HIV/HCV coinfecti
Externí odkaz:
https://doaj.org/article/3f03854a3efb4042a1a0352f586949cf
Autor:
Raphael J Landovitz, Sue Li, Beatriz Grinsztejn, Halima Dawood, Albert Y Liu, Manya Magnus, Mina C Hosseinipour, Ravindre Panchia, Leslie Cottle, Gordon Chau, Paul Richardson, Mark A Marzinke, Craig W Hendrix, Susan H Eshleman, Yinfeng Zhang, Elizabeth Tolley, Jeremy Sugarman, Ryan Kofron, Adeola Adeyeye, David Burns, Alex R Rinehart, David Margolis, William R Spreen, Myron S Cohen, Marybeth McCauley, Joseph J Eron
Publikováno v:
PLoS Medicine, Vol 15, Iss 11, p e1002690 (2018)
BACKGROUND:Cabotegravir (CAB) is a novel strand-transfer integrase inhibitor being developed for HIV treatment and prevention. CAB is formulated both as an immediate-release oral tablet for daily administration and as a long-acting injectable suspens
Externí odkaz:
https://doaj.org/article/830d37bc7c0d4f32b2594bc89a7448f5
Autor:
Jennifer S Lee, Stephen R Cole, Chad J Achenbach, Dirk P Dittmer, David B Richardson, William C Miller, Christopher Mathews, Keri N Althoff, Richard D Moore, Joseph J Eron, Center for AIDS Research (CFAR) Network of Integrated Clinical Systems (CNICS)
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0197665 (2018)
BACKGROUND:Cancer causes significant morbidity and mortality among HIV patients in the US due to extended life expectancy with access to effective antiretroviral therapy. Low, detectable HIV RNA has been studied as a risk factor for adverse health ou
Externí odkaz:
https://doaj.org/article/ca073d71e11448c8afa6d88713ba0c4f
Autor:
Allison S Thomas, Kimberley L Jones, Rajesh T Gandhi, Deborah K McMahon, Joshua C Cyktor, Dora Chan, Szu-Han Huang, Ronald Truong, Alberto Bosque, Amanda B Macedo, Colin Kovacs, Erika Benko, Joseph J Eron, Ronald J Bosch, Christina M Lalama, Samuel Simmens, Bruce D Walker, John W Mellors, R Brad Jones
Publikováno v:
PLoS Pathogens, Vol 13, Iss 9, p e1006629 (2017)
HIV-specific CD8+ T-cell responses limit viral replication in untreated infection. After the initiation of antiretroviral therapy (ART), these responses decay and the infected cell population that remains is commonly considered to be invisible to T-c
Externí odkaz:
https://doaj.org/article/296cd3ee852f419ca1a0fd1c12dbd3c1
Autor:
Rajesh T Gandhi, Deborah K McMahon, Ronald J Bosch, Christina M Lalama, Joshua C Cyktor, Bernard J Macatangay, Charles R Rinaldo, Sharon A Riddler, Evelyn Hogg, Catherine Godfrey, Ann C Collier, Joseph J Eron, John W Mellors, ACTG A5321 Team
Publikováno v:
PLoS Pathogens, Vol 13, Iss 4, p e1006285 (2017)
Antiretroviral therapy (ART) reduces levels of HIV-1 and immune activation but both can persist despite clinically effective ART. The relationships among pre-ART and on-ART levels of HIV-1 and activation are incompletely understood, in part because p
Externí odkaz:
https://doaj.org/article/e23b467e146343519a722fb4f0ce14e8
Autor:
Terra V Fatukasi, Stephen R Cole, Richard D Moore, William C Mathews, Jessie K Edwards, Joseph J Eron, CNICS investigators
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180843 (2017)
Prompt initiation of combination antiretroviral therapy (ART) is important to reduce comorbidity and mortality among people living with HIV, especially for those with a low CD4 cell count. However there is evidence that not everyone receives prompt i
Externí odkaz:
https://doaj.org/article/75f1396eabe541b18e5c2d08ba86f931
Autor:
Anna B Cope, Kimberly A Powers, JoAnn D Kuruc, Peter A Leone, Jeffrey A Anderson, Li-Hua Ping, Laura P Kincer, Ronald Swanstrom, Victoria L Mobley, Evelyn Foust, Cynthia L Gay, Joseph J Eron, Myron S Cohen, William C Miller
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0127950 (2015)
HIV transmission is influenced by status awareness and receipt of care and treatment. We analyzed these attributes of named partners of persons with acute HIV infection (index AHI cases) to characterize the transmission landscape in North Carolina (N
Externí odkaz:
https://doaj.org/article/2ed85e5a698346efb53be589278418ea
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88512 (2014)
Transmission of HIV continues in the United States (US), despite prevention efforts aimed at education and treatment. Concurrently, drug resistance in HIV, particularly in patients being infected with HIV for the first time, poses a threat to the con
Externí odkaz:
https://doaj.org/article/ccd0616caf62451c827b6cd505d89f26