Zobrazeno 1 - 10
of 170
pro vyhledávání: '"Joseph J, Shatzel"'
Autor:
Norah G. Verbout, Christina U. Lorentz, Brandon D. Markway, Michael Wallisch, Thomas C. Marbury, Enrico Di Cera, Joseph J. Shatzel, András Gruber, Erik I. Tucker
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-11 (2024)
Abstract Background The protein C system regulates blood coagulation, inflammation, and vascular integrity. AB002 is an injectable protein C activating enzyme under investigation to safely prevent and treat thrombosis. In preclinical models, AB002 is
Externí odkaz:
https://doaj.org/article/de9625889c004a0a9813402404b9f1bc
Autor:
Martin A Schreiber, Danielle F Peterson, Natasha S McKibben, Catherine E Hutchison, Karalynn Lancaster, Chih Jen Yang, Graham J Dekeyser, Darin M Friess, Nick J Willett, Joseph J Shatzel, Joseph E Aslan, Zachary M Working
Publikováno v:
BMJ Open, Vol 13, Iss 3 (2023)
Introduction Orthopaedic trauma and fracture care commonly cause perioperative anaemia and associated functional iron deficiency due to a systemic inflammatory state. Modern, strict transfusion thresholds leave many patients anaemic; managing this pe
Externí odkaz:
https://doaj.org/article/85118c67fe91496ea69fcfa215710802
Autor:
Tia C.L. Kohs, Patricia Liu, Vikram Raghunathan, Ramin Amirsoltani, Michael Oakes, Owen J.T. McCarty, Sven R. Olson, Luke Masha, David Zonies, Joseph J. Shatzel
Publikováno v:
Platelets, Vol 33, Iss 4, Pp 570-576 (2022)
Extracorporeal membrane oxygenation (ECMO) provides lifesaving circulatory support and gas exchange, although hematologic complications are frequent. The relationship between ECMO and severe thrombocytopenia (platelet count
Externí odkaz:
https://doaj.org/article/39b0a3c5f9d4443585ce668e80b46587
Autor:
Iván Parra-Izquierdo, Alexander R. Melrose, Jiaqing Pang, Hari Hara Sudhan Lakshmanan, Stéphanie E. Reitsma, Sai Hitesh Vavilapalli, Mark K. Larson, Joseph J. Shatzel, Owen J. T. McCarty, Joseph E. Aslan
Publikováno v:
Platelets, Vol 33, Iss 3, Pp 404-415 (2022)
Several Janus kinase (JAK) inhibitors (jakinibs) have recently been approved to treat inflammatory, autoimmune and hematological conditions. Despite emerging roles for JAKs and downstream signal transducer and activator of transcription (STAT) protei
Externí odkaz:
https://doaj.org/article/39b1104d776a4aa682c0497f47e4622c
Autor:
Ingrid Lindquist, Sven R. Olson, Ang Li, Hanny Al‐Samkari, Janice H. Jou, Owen J. T. McCarty, Joseph J. Shatzel
Publikováno v:
Platelets, Vol 33, Iss 1, Pp 66-72 (2022)
Thrombopoietin receptor agonists (TPO-RAs) can mitigate preprocedural thrombocytopenia in patients with chronic liver disease (CLD) however their effects on procedural outcomes is unclear. In this meta-analysis, we aimed to better define the efficacy
Externí odkaz:
https://doaj.org/article/88afb6d1b9a94cb788f20f81779f13fe
Autor:
Joseph J. Shatzel, Emma P. DeLoughery, Christina U. Lorentz, Erik I. Tucker, Joseph E. Aslan, Monica T. Hinds, David Gailani, Jeffrey I. Weitz, Owen J. T. McCarty, Andras Gruber
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 4, Iss 4, Pp 500-505 (2020)
Abstract Coronavirus disease 2019 (COVID‐19) is predicted to overwhelm health care capacity in the United States and worldwide, and, as such, interventions that could prevent clinical decompensation and respiratory compromise in infected patients a
Externí odkaz:
https://doaj.org/article/a59e582344824c618e4a5df1c66f6ef4
Autor:
Benjamin K. Elstrott, Hari H.S. Lakshmanan, Alexander R. Melrose, Kelley R. Jordan, Kylee L. Martens, Chih‐Jen Yang, Danielle F. Peterson, Hannah Stowe McMurry, Corinne Lavasseur, Jamie O. Lo, Sven R. Olson, Thomas G. DeLoughery, Joseph E. Aslan, Joseph J. Shatzel
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 6, Iss 2, Pp n/a-n/a (2022)
Abstract Background Iron deficiency anemia (IDA) and heavy menstrual bleeding are prevalent, interrelated issues impacting over 300 million premenopausal women worldwide. IDA is generally associated with increased platelet counts; however, the effect
Externí odkaz:
https://doaj.org/article/7bf3a8b21e004c149e84f7d2b79c6d4e
Publikováno v:
Platelets, Vol 32, Iss 4, Pp 437-439 (2021)
Externí odkaz:
https://doaj.org/article/673dfbc3626f471c975f5a53f3a22f17
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 3, Iss 3, Pp 498-502 (2019)
Abstract Despite therapeutic anticoagulation, patients with venous thromboembolism (VTE) not uncommonly present with findings of progressive thrombosis, sometimes within the first several weeks of treatment. While the prevailing strategy in these sce
Externí odkaz:
https://doaj.org/article/83352642b4a84411b70b1b5cd90df611
Autor:
Vikram Raghunathan, Jevgenia Zilberman‐Rudenko, Sven R. Olson, Florea Lupu, Owen J. T. McCarty, Joseph J. Shatzel
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 3, Iss 3, Pp 331-339 (2019)
Abstract The contact pathway factors XI (FXI) and XII (FXII) have been demonstrated to be largely dispensable for hemostasis, as their absence results in a mild to absent bleeding diathesis. A growing body of literature, however, suggests that the co
Externí odkaz:
https://doaj.org/article/0cc50be903824b2e926d972c9677fae5