Zobrazeno 1 - 10 of 34 pro vyhledávání: '"Joseph J, Grudzinski"'
1
Akademický článek
Clinical Imaging and Dosimetry of a Pan-Cancer Targeting Alkylphosphocholine Analog, [124I]I-NM404
Autor: Joseph J. Grudzinski, Lance T. Hall, Steve Cho, Glenn Liu, Anne Traynor, Matthew H. Lee, Marc Longino, Anatoly Pinchuk, Christine Jaskowiak, Bryan Bednarz, Jamey Weichert, John S. Kuo
Publikováno v: Radiation, Vol 2, Iss 2, Pp 215-227 (2022)
The purpose of this study was to assess organ dosimetry and clinical use of [124I]I-NM404, a radiotheranostic alkylphosphocholine (APC) analog, for accurate detection and characterization of a wide variety of solid primary and metastatic malignancies
Externí odkaz: https://doaj.org/article/e3f05a37417341fb9f65fc1724e8f472
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2
Akademický článek
Image-Based Dosimetry in Dogs and Cross-Reactivity with Human Tissues of IGF2R-Targeting Human Antibody
Autor: Kevin J. H. Allen, Ohyun Kwon, Matthew R. Hutcheson, Joseph J. Grudzinski, Stuart M. Cain, Frederic A. Cruz, Remitha M. Vinayakamoorthy, Ying S. Sun, Lindsay Fairley, Chandra B. Prabaharan, Ryan Dickinson, Valerie MacDonald-Dickinson, Maruti Uppalapati, Bryan P. Bednarz, Ekaterina Dadachova
Publikováno v: Pharmaceuticals, Vol 16, Iss 7, p 979 (2023)
Background: Osteosarcoma (OS) represents the most common primary bone tumor in humans and in companion dogs, being practically phenotypically identical. There is a need for effective treatments to extend the survival of patients with OS. Here, we exa
Externí odkaz: https://doaj.org/article/c4e817e3f39f4e6b99757ca74f03bafa
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3
Akademický článek
Developments in Combining Targeted Radionuclide Therapies and Immunotherapies for Cancer Treatment
Autor: Caroline P. Kerr, Joseph J. Grudzinski, Thanh Phuong Nguyen, Reinier Hernandez, Jamey P. Weichert, Zachary S. Morris
Publikováno v: Pharmaceutics, Vol 15, Iss 1, p 128 (2022)
Targeted radionuclide therapy (TRT) and immunotherapy are rapidly growing classes of cancer treatments. Basic, translational, and clinical research are now investigating therapeutic combinations of these agents. In comparison to external beam radiati
Externí odkaz: https://doaj.org/article/03b157f0bf9b43879e7cd003d2a058cd
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4
Image-Based Dosimetry in Dogs and Cross-Reactivity with Human Tissues of IGF2R-Targeting Human Antibody
Autor: Dadachova, Kevin J. H. Allen, Ohyun Kwon, Matthew R. Hutcheson, Joseph J. Grudzinski, Stuart M. Cain, Frederic A. Cruz, Remitha M. Vinayakamoorthy, Ying S. Sun, Lindsay Fairley, Chandra B. Prabaharan, Ryan Dickinson, Valerie MacDonald-Dickinson, Maruti Uppalapati, Bryan P. Bednarz, Ekaterina
Publikováno v: Pharmaceuticals; Volume 16; Issue 7; Pages: 979
Background: Osteosarcoma (OS) represents the most common primary bone tumor in humans and in companion dogs, being practically phenotypically identical. There is a need for effective treatments to extend the survival of patients with OS. Here, we exa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=multidiscipl::8453329f586d7aac5a60772c05fe3d85
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6
Creation of waterproof, TLD probes for dose measurements to validate image-based radiopharmaceutical therapy dosimetry workflow
Autor: David P Adam, Clifford Hammer, Julia Ziege Malyshev, Wesley S Culberson, Tyler J Bradshaw, Joseph J Grudzinski, Paul M Harari, Bryan P Bednarz
Publikováno v: Biomedical Physics & Engineering Express. 9:045010
Voxel-level dosimetry based on nuclear medicine images offers patient-specific personalization of radiopharmaceutical therapy (RPT) treatments. Clinical evidence is emerging demonstrating improvements in treatment precision in patients when voxel-lev
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7be7acda2048804cce7f21f0657f91a2
https://doi.org/10.1088/2057-1976/accf22
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9
Validation of Monte Carlo
Autor: David P, Adam, Joseph J, Grudzinski, Ian, Bormett, Benjamin L, Cox, Ian R, Marsh, Tyler J, Bradshaw, Paul M, Harari, Bryan P, Bednarz
Publikováno v: Medical physics. 49(8)
Approximately 50% of head and neck cancer (HNC) patients will experience loco-regional disease recurrence following initial courses of therapy. Retreatment with external beam radiotherapy (EBRT) is technically challenging and may be associated with a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::79c71316b4de8725b07d9a31e3f65d86
https://pubmed.ncbi.nlm.nih.gov/35607296
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10
Validation of Monte Carlo Iodine-131 radiopharmaceutical dosimetry workflow using a 3D printed anthropomorphic head and neck phantom
Autor: David P. Adam, Joseph J. Grudzinski, Ian Bormett, Benjamin L. Cox, Ian R. Marsh, Tyler J. Bradshaw, Paul M. Harari, Bryan P. Bednarz
Purpose: In this study, we present the creation of an anthropomorphic, head and neck, nuclear medicine phantom and its characterization for the validation of a Monte Carlo, SPECT image based, Iodine-131 RPT dosimetry workflow. Methods: 3D printing te
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed4ba551b4b1c23d43992515bf9ad2a3
http://arxiv.org/abs/2202.01847
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