Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Joseph Ilan"'
Autor:
Ilana Ariel, Mark L. Tykocinski, Martin Fischer, Joseph Ilan, Stela Miron, Dymitr Komitowski, Alexander Shevelev, Ekkehard Schulze, Abraham Hochberg, Mark J. Cooper, Nathan de Groot
Publikováno v:
The Journal of Urology. :2120-2127
Developmentally imprinted genes, such as H19 and insulin-like growth factor-II (IGF-II), play an important role during human embryogenesis and also have been implicated in the pathogenesis of embryonal tumors of childhood. Since H19 is expressed in h
Publikováno v:
Molecular Reproduction and Development. 43:180-186
There are several cell types within the placenta that produce cytokines which can contribute to the regulatory mechanisms that ensure normal pregnancy. The immunological milieu at the maternofetal interface is considered to be crucial for survival of
Autor:
Judith Ilan, O. Abramasky, Joseph Ilan, O. Farges, Jerzy Trojan, C. Lafarge‐Frayssinet, T R Johnson, José Uriel, M. Hajeri-Germond, Y. Pan, X. Naval
Publikováno v:
Molecular Reproduction and Development. 42:369-378
Alphafetoprotein (AFP), a major serum protein synthesized during the embryo-fetal and postnatal period (in the yolk sac, then in the liver), is also an oncoprotein. The intracellular presence of AFP and of serum albumin (SA) in normal and neoplastic
Autor:
Joseph Ilan, Jean-Denis Rouzeau, Monique Lazar, Noël Lamandé, François Gros, Angélica Keller, Sophie Brosset, Marguerite Lucas, T R Johnson
Publikováno v:
Molecular Reproduction and Development. 41:306-313
The glycolytic enzyme enolase (EC 4.2.1.11) exists as dimers formed from three structurally related subunits α, β, and γ, encoded by separate genes. The gene encoding the β-subunit is expressed only in striated muscles. We have previously shown t
Autor:
Jerzy Trojan, Thomas R. Johnson, Susan D. Rudin, Judith Ilan, Mark L. Tykocinski, Joseph Ilan
Publikováno v:
Science. 259:94-97
Rat C6 glioma cells express insulin-like growth factor I (IGF-I) and form rapidly growing tumors in syngeneic animals. When transfected with an episome-based vector encoding antisense IGF-I complementary DNA, these cells lost tumorigenicity. Subcutan
The third IGF-II promoter specifies transcription of three transcripts out of five in human placenta
Publikováno v:
Molecular Reproduction and Development. 33:413-417
Insulin-like growth factor-II (IGF-II) mRNA exists as multiple transcript size classes, such as 6.0, 5.3, 4.9, 3.2, and 2.2 kb mRNAs in various human tissues. Three different promoters, 2 different polyadenylation sites, and alternative splicing are
Publikováno v:
Molecular Reproduction and Development. 30:95-99
The stability of several RNA transcripts in cultured hepatocytes is known to increase when serum is omitted from the culture medium. In order to investigate possible mechanisms for this phenomenon, we examined the effects of actinomycin D and cyclohe
Autor:
Frauke Rininsland, Thomas R. Johnson, Cheryl L. Chernicky, Ekkehard Schulze, Peter Burfeind, Judith Ilan, Joseph Ilan
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 94(11)
Homopurine (AG) and homopyrimidine (CT) oligodeoxyribonucleotides predicted to form triple-helical (triplex) structures have been shown to specifically suppress gene expression when supplied to cultured cells. Here we present evidence that homopurine
Autor:
Donald D. Anthony, Yajun Guo, Jerzy Trojan, L.C. Upegui-Gonzalez, Huynh T. Duc, Joseph Ilan, Frédéric Hor
Publikováno v:
Neuroscience letters. 212(1)
Tumor cells frequently express the insulin-like growth factor I (IGF-I). Recently we demonstrated that rat glioma cells when transfected with a vector encoding antisense IGF-I cDNA lost tumorigenicity and induced a tumor specific immune response invo
Autor:
Ralph B. L. Gwatkin, Judith Ilan, T R Johnson, Joseph Ilan, Huiqing Tan, C. L. Chernicky, R. W. Redline
Publikováno v:
Molecular reproduction and development. 37(4)
Insulin-like growth factors (IGF-I and IGF-II) play an important regulatory role in fetal growth and development. Alterations in expression of these growth factors may result in developmental abnormalities, macrosomia, and intrauterine growth retarda